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Every year, about one million new cases of colon cancer are diagnosed worldwide. About 150,000 new cases are detected each year in the United States. Over a lifetime, about 1 in 19 people develop colon cancer and nearly 50,000 people are expected to die from it in the U.S. this year. According to the American Cancer Society, colon cancer is the third leading cause of cancer-related death in the U.S., accounting for about 10 percent of all cancer deaths.
Epigenetic changes drive successful metastases of pancreatic cancer cells

Epigenetic changes drive successful metastases of pancreatic cancer cells

A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells. [More]
Study reveals importance of glutamine metabolism for colon cancer

Study reveals importance of glutamine metabolism for colon cancer

The importance of glutamine was made clear as a colon cancer specific metabolism. It is known that glutamine metabolism is important for pancreatic cancer, but the importance of glutamine metabolism for colon cancer has been unclear. [More]
Nanodiscs deliver customized therapeutic vaccine for treatment of colon, melanoma cancers

Nanodiscs deliver customized therapeutic vaccine for treatment of colon, melanoma cancers

Researchers at the University of Michigan have had initial success in mice using nanodiscs to deliver a customized therapeutic vaccine for the treatment of colon and melanoma cancer tumors. [More]
HCI receives $8.8 million NIH grant to lead colon cancer study

HCI receives $8.8 million NIH grant to lead colon cancer study

Huntsman Cancer Institute at the University of Utah will head an international study to find out how lifestyle and other health factors impact colon and rectal cancer outcomes. [More]
Capsule endoscopy could help avoid unnecessary hospitalizations for patients with GI bleeding

Capsule endoscopy could help avoid unnecessary hospitalizations for patients with GI bleeding

Symptoms of possible upper GI bleeding (UGIB) are a leading cause of hospital admissions through emergency departments. [More]
Researchers use patient prostate tissue to create new model for cancer research

Researchers use patient prostate tissue to create new model for cancer research

For the first time, researchers have been able to grow, in a lab, both normal and primary cancerous prostate cells from a patient, and then implant a million of the cancer cells into a mouse to track how the tumor progresses. [More]
Anti-platelet drug may slow spread of colon and pancreatic cancer cells

Anti-platelet drug may slow spread of colon and pancreatic cancer cells

Researchers from Oregon Health and Science University have found that aspirin may slow the spread of some types of colon and pancreatic cancer cells. The paper is published in the American Journal of Physiology—Cell Physiology. [More]
Oral cavity bacterium linked to development and progression of esophageal cancer

Oral cavity bacterium linked to development and progression of esophageal cancer

A type of bacterium usually found in the human mouth, Fusobacterium nucleatum, has been found to be related to the prognosis of esophageal cancer in Japanese patients by researchers from Kumamoto University, Japan. [More]
Researchers discover biological pathway that plays vital role in tumor development

Researchers discover biological pathway that plays vital role in tumor development

An international team led by researchers from the Technion-Israel Institute of Technology's Rappaport Faculty of Medicine and the Technion Integrated Cancer Center has discovered a biological pathway that plays an important role in tumor development. [More]
Study shows involvement of lipid metabolism in tumour metastasis

Study shows involvement of lipid metabolism in tumour metastasis

A study headed by Salvador Aznar Benitah, ICREA researcher at the Institute for Research in Biomedicine, and published today in Nature identifies metastasis-initiating cells through a specific marker, namely the protein CD36. [More]
Study shows heart medications prevent cardiovascular damage during breast cancer treatment

Study shows heart medications prevent cardiovascular damage during breast cancer treatment

Heart medication taken in combination with chemotherapy reduces the risk of serious cardiovascular damage in patients with early-stage breast cancer, according to results from a new landmark clinical trial. [More]
Early life history and genetics may play crucial role in shaping gut microbiome

Early life history and genetics may play crucial role in shaping gut microbiome

Genetics and birthplace have a big effect on the make-up of the microbial community in the gut, according to research published Nov. 28. in the journal Nature Microbiology. [More]
Asian Americans at risk for type 2 diabetes less likely to undergo recommended screening, study finds

Asian Americans at risk for type 2 diabetes less likely to undergo recommended screening, study finds

Less than half of Asian Americans who ought to be screened for type 2 diabetes actually get tested, according to a study published Nov. 15, 2016, in the Journal of General Internal Medicine. [More]
Virginia Tech and CytImmune Sciences develop more effective and less toxic cancer treatment

Virginia Tech and CytImmune Sciences develop more effective and less toxic cancer treatment

Virginia Tech scientists have developed a new cancer drug that uses gold nanoparticles created by the biotech firm CytImmune Sciences to deliver paclitaxel — a commonly used chemotherapy drug directly to a tumor. [More]
Exposure to licorice compound disrupts steroid sex hormone production in ovary

Exposure to licorice compound disrupts steroid sex hormone production in ovary

A study of mouse reproductive tissues finds that exposure to isoliquiritigenin, a compound found in licorice, disrupts steroid sex hormone production in the ovary, researchers report. [More]
New research explains how tumors may impair ability of the liver to respond to caloric deprivation

New research explains how tumors may impair ability of the liver to respond to caloric deprivation

One of the worst cruelties of lethal cancer is the phenomenon called wasting, or in medical terms, cachexia (pronounced ka-CHEX-ia), in which a patient seems literally to diminish in bodily terms as the cancer ravages one or more internal organs. [More]
Scientists identify new way to block action of genetic mutations found in most cancers

Scientists identify new way to block action of genetic mutations found in most cancers

Researchers at the University of Illinois at Chicago have identified a new way to block the action of genetic mutations found in nearly 30 percent of all cancers. [More]
Researchers create new culture model of human intestine to study inflammatory bowel disease

Researchers create new culture model of human intestine to study inflammatory bowel disease

Inflammatory bowel disease (IBD) is a complex condition that requires a lifetime of care and increases a person's cancer risk. [More]
Penn study reveals new sights into how some intestinal cells can withstand chemotherapy and radiation

Penn study reveals new sights into how some intestinal cells can withstand chemotherapy and radiation

When treating cancer with chemotherapy and radiation, decisions about dose must walk a fine line between attacking cancerous cells and preserving healthy ones. [More]
WSU researchers identify potential new diagnostic tool for early detection of colorectal cancer

WSU researchers identify potential new diagnostic tool for early detection of colorectal cancer

Scientists at Washington State University and Johns Hopkins Medical School have discovered a fast, noninvasive method that could lead to the early diagnosis of colorectal cancer. [More]
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