Colon Cancer News and Research RSS Feed - Colon Cancer News and Research

Every year, about one million new cases of colon cancer are diagnosed worldwide. About 150,000 new cases are detected each year in the United States. Over a lifetime, about 1 in 19 people develop colon cancer and nearly 50,000 people are expected to die from it in the U.S. this year. According to the American Cancer Society, colon cancer is the third leading cause of cancer-related death in the U.S., accounting for about 10 percent of all cancer deaths.
Curbing immune system infighting could make treatment more effective for pancreatic cancer

Curbing immune system infighting could make treatment more effective for pancreatic cancer

Internal conflict between cell types explains why the immune system struggles to recognize and attack pancreatic cancer. [More]
U-M study casts doubt on possible link between obesity and imbalance of microbes

U-M study casts doubt on possible link between obesity and imbalance of microbes

For people with weight problems, news headlines in recent years may have brought relief, as researchers studying the microscopic creatures inside our bodies reported possible links between obesity and an out-of-whack balance of microbes. [More]
Colorectal tumors present epigenetic heterogeneity, study finds

Colorectal tumors present epigenetic heterogeneity, study finds

A new study led by Dr. Manel Esteller, Director of the Epigenetics and Cancer Biology Program of Bellvitge Biomedical Research Institute, ICREA researcher and Professor of Genetics at University of Barcelona discovers that colorectal tumors present epigenetic heterogeneity that relates to the clinical course of the disease. [More]
Novel marine natural product appears to reduce pancreatic tumor size

Novel marine natural product appears to reduce pancreatic tumor size

Scientists at Florida Atlantic University's Harbor Branch Oceanographic Institute found that a deep-water marine sponge collected off of Fort Lauderdale's coast contains leiodermatolide, a natural product that has the ability to inhibit the growth of cancer cells as well as block cancer cells from dividing using extremely low concentrations of the compound. [More]
Greater screening can help improve colorectal cancer rates among Hispanic men in California

Greater screening can help improve colorectal cancer rates among Hispanic men in California

Colorectal cancer incidence and mortality rates in California have decreased markedly for men and women in all major racial-ethnic groups since 1990, except for Hispanic men. [More]
Gut microbiome can influence common dietary compound linked to heart disease

Gut microbiome can influence common dietary compound linked to heart disease

In the last five years, some scientists have cautioned against eating eggs and meat because these foods generate a common dietary compound, trimethylamine N-oxide (TMAO), that research has suggested plays a role in heart disease. [More]
Gasotransmitters in the body could potentially be used to develop new drugs

Gasotransmitters in the body could potentially be used to develop new drugs

Gases once thought of only as environmental pollutants are now known to be produced by the body. They could potentially be used to develop drugs to treat diseases including heart failure and cancer. [More]
New study shows hedgehog signalling offers protection against colon cancer

New study shows hedgehog signalling offers protection against colon cancer

Many types of cancer are caused by gene mutations in the signalling pathways that control cell growth, such as the hedgehog signalling pathway. [More]
Research could help develop better therapies for new subtype of adenocarcinoma  patients

Research could help develop better therapies for new subtype of adenocarcinoma patients

Lung cancer is the most common cause of cancer deaths, accounting for about a third of all tumor-related deaths. Adenocarcinomas, a non-small cell lung cancer (NSCLC), account for about 40 percent of cancer diagnoses, but few treatments are available for the disease. [More]
Triple-combination therapy patch shrinks tumors, prevents recurrence in colon cancer mice model

Triple-combination therapy patch shrinks tumors, prevents recurrence in colon cancer mice model

Investigators at Brigham and Women's Hospital have developed a hydrogel patch that can adhere to tumors in a preclinical model of colon cancer, delivering a local, combination treatment as the elastic gel breaks down over time. [More]
Researchers discover genetic changes in MSH3 gene in patients with hereditary colon cancer

Researchers discover genetic changes in MSH3 gene in patients with hereditary colon cancer

The formation of large numbers of polyps in the colon has a high probability of developing into colon cancer, if left untreated. [More]
Salmonella protein can reduce drug resistant molecule found in cancer cells

Salmonella protein can reduce drug resistant molecule found in cancer cells

A surprising result in an experiment on Salmonella bacteria has led to a discovery that may make drug resistant cancer cells more treatable by conventional chemotherapies. [More]
Combination of two plant compounds holds promise in treating colon cancer

Combination of two plant compounds holds promise in treating colon cancer

The combination of two plant compounds that have medicinal properties - curcumin and silymarin - holds promise in treating colon cancer, according Saint Louis University research published in the June 23 issue of the Journal of Cancer. [More]
Study uncovers new drug-gene mutation combinations that can kill cancer cells

Study uncovers new drug-gene mutation combinations that can kill cancer cells

In an effort to expand the number of cancer gene mutations that can be specifically targeted with personalized therapies, researchers at University of California San Diego School of Medicine and Moores Cancer Center looked for combinations of mutated genes and drugs that together kill cancer cells. [More]
Researchers developing and validating model to predict risk for colon cancer in people under 50

Researchers developing and validating model to predict risk for colon cancer in people under 50

While the incidence of colon cancer has been declining in individuals 50 years old and older in the United States, it is steadily rising in those under age 50. With funding from the U.S. Department of Veterans Affairs, Thomas F. Imperiale, M.D., a VA and Regenstrief Institute clinician-researcher, is developing and validating a model to predict risk for colon cancer in those under 50 with no family history of the disease. [More]
Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

Researchers identify unique mechanism to suppress colorectal cancer tumors in mice

A new scientific study has identified why colorectal cancer cells depend on a specific nutrient, and a way to starve them of it. Over one million men and women are living with colorectal cancer in the United States. [More]
Adjuvant chemotherapy may improve survival in stage 2 colon cancer patients

Adjuvant chemotherapy may improve survival in stage 2 colon cancer patients

Researchers and physicians have grappled with the role of "adjuvant," or post-surgery, chemotherapy for patients with early-stage colon cancer, even for cancers considered high risk. [More]
Gut microbiota could influence person's likelihood of developing colon cancer

Gut microbiota could influence person's likelihood of developing colon cancer

The microscopic organisms that live in our gut do more than help us digest food. A new study in rats bolsters a growing body of evidence that the complex mix of microorganisms found in the gut, known as gut microbiota, could influence a person's likelihood of developing colon cancer. [More]
Pancreatic cysts increase overall risk of pancreatic cancer, study shows

Pancreatic cysts increase overall risk of pancreatic cancer, study shows

A look back at more than half a million patient records has established that patients with pancreatic cysts have a significantly higher overall risk of pancreatic cancer compared to those without such cysts, according to a study in the July issue of GIE: Gastrointestinal Endoscopy, the journal of the American Society for Gastrointestinal Endoscopy. [More]
Recellularized colon model helps identify cancer driver genes involved in CRC progression

Recellularized colon model helps identify cancer driver genes involved in CRC progression

Genetic mutations are a major cause of cancer, and tracking the role of each gene in cancer pathogenesis has long been an important tool in the fight against a disease that is expected to kill more than 1.6 million people this year. [More]
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