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Every year, about one million new cases of colon cancer are diagnosed worldwide. About 150,000 new cases are detected each year in the United States. Over a lifetime, about 1 in 19 people develop colon cancer and nearly 50,000 people are expected to die from it in the U.S. this year. According to the American Cancer Society, colon cancer is the third leading cause of cancer-related death in the U.S., accounting for about 10 percent of all cancer deaths.
Retrospective study finds overuse of colonoscopies for colorectal cancer screening, surveillance

Retrospective study finds overuse of colonoscopies for colorectal cancer screening, surveillance

A retrospective study led by researchers at Brigham and Women's Hospital (BWH), has found an overuse of colonoscopies for colorectal cancer screening and surveillance. [More]
Arisaph Pharmaceuticals receives STTR grants to develop cancer drug candidates

Arisaph Pharmaceuticals receives STTR grants to develop cancer drug candidates

Arisaph Pharmaceuticals, Inc., a privately held biopharmaceutical company focused on discovery and development of novel therapies for cardiometabolic diseases and cancer, announced today that it has been awarded a phase II Small Business Technology Transfer (STTR) grant and a supplemental phase I grant, both from the National Cancer Institute of the National Institutes of Health. [More]
EMD Serono declares winners of first Grant for Oncology Innovation

EMD Serono declares winners of first Grant for Oncology Innovation

EMD Serono, the biopharmaceutical division of Merck KGaA, Darmstadt, Germany, today announced the winners of the first Grant for Oncology Innovation (GOI), who will receive grants totaling $1.3 million. [More]
AIT, BioVendor and SCIENION partner to develop in-vitro diagnostic test for colon cancer

AIT, BioVendor and SCIENION partner to develop in-vitro diagnostic test for colon cancer

The AIT Austrian Institute of Technology, BioVendor and SCIENION today announced that the three companies will partner on the development of an in-vitro diagnostic test for colon cancer. The innovative test kit shall identify cancer at an early stage based on tumor autoantibody biomarkers. [More]
Disrupting cancer regulator MYC: an interview with Professor Kim Janda

Disrupting cancer regulator MYC: an interview with Professor Kim Janda

MYC is an oncogenic member of the basic helix-loop-helix-leucine zipper transcription factor family. In its monomeric form, MYC’s tertiary structure is intrinsically disordered and the protein is transcriptionally inactive. [More]
Researchers discover genetic factors involved in development of early-onset ulcerative colitis

Researchers discover genetic factors involved in development of early-onset ulcerative colitis

UCLA researchers were part of a team that has discovered the interplay of several genetic factors that may be involved in the development of early-onset ulcerative colitis, a severe type of inflammatory bowel disease. [More]
USPSTF lung cancer screening recommendations in high-risk Medicare beneficiaries is cost effective

USPSTF lung cancer screening recommendations in high-risk Medicare beneficiaries is cost effective

Questions regarding effectiveness, infrastructure and cost effectiveness of low-dose computed tomography (CT) screening of those at high risk for lung cancer have now been answered. Medicare should rapidly provide full national coverage for these exams. [More]
Irinotecan-based therapy improves survival rates for patients with stage III colon cancer

Irinotecan-based therapy improves survival rates for patients with stage III colon cancer

A subset of patients with stage III colon cancer had improved survival rates when treated with irinotecan-based therapy, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association. [More]
Study shows new role for protein APC in suppressing colorectal cancer

Study shows new role for protein APC in suppressing colorectal cancer

A study recently published in the journal Carcinogenesis by researchers at the University of Kansas shows a new role for the protein adenomatous polyposis coli (APC) in suppressing colorectal cancer - the second-leading cause of cancer-related deaths in the U.S. [More]
Overweight and obesity linked to 10 common cancers and over 12 000 cases every year in the UK

Overweight and obesity linked to 10 common cancers and over 12 000 cases every year in the UK

A higher body mass index (BMI) increases the risk of developing 10 of the most common cancers, the largest study of its kind on BMI and cancer, involving more than 5 million adults in the UK, published in The Lancet shows. [More]
MicroVAX begins phase I clinical trial for proprietary cancer vaccine platform

MicroVAX begins phase I clinical trial for proprietary cancer vaccine platform

MicroVAX, LLC, a biotech company located in Manassas, Virginia announced today the commencement of a phase I clinical trial for its unique and proprietary vaccine platform that allows under the provisions of an FDA IND entry of patients with cancers of the, breast, prostate, colon, ovary and lung, that have relapsed after initial salvage therapy. [More]
Screening test for colon cancer wins FDA approval

Screening test for colon cancer wins FDA approval

The test, called Cologuard, can detect genetic mutations in patients' stool samples that are associated with cancerous and precancerous growths. [More]
First Edition: August 12, 2014

First Edition: August 12, 2014

Today's headlines include stories about how the federal government's experience with healthcare.gov has led to the creation of the U.S. Digital Service. [More]
American Journal of Public Health special issue to highlight health disparities among Veterans Affairs

American Journal of Public Health special issue to highlight health disparities among Veterans Affairs

In an online-only, open access special issue of the American Journal of Public Health, researchers investigate issues of health equity, quality and disparities within the Veterans Affairs health care system. [More]
New guideline recommends genetic testing of tumors for colorectal cancer patients

New guideline recommends genetic testing of tumors for colorectal cancer patients

Of the 143,000 patients diagnosed with colorectal cancer annually in the U.S., up to 25 percent have a familial risk of colorectal cancer. A new guideline from the U.S. Multi-Society Task Force on Colorectal Cancer recommends genetic testing of tumors for all newly diagnosed colorectal cancer patients. [More]
New web-based tool enables researchers to quickly visualize genomic information

New web-based tool enables researchers to quickly visualize genomic information

Scientists at the University of Maryland have developed a new, web-based tool that enables researchers to quickly and easily visualize and compare large amounts of genomic information resulting from high-throughput sequencing experiments. [More]

New versatile method for making artificial anti-cancer molecules in minutes

Researchers have developed a simple and versatile method for making artificial anti-cancer molecules that mimic the properties of one of the body's natural defence systems. [More]
University of Bradford researchers devise simple blood test to diagnose cancer

University of Bradford researchers devise simple blood test to diagnose cancer

Researchers from the University of Bradford, UK, have devised a simple blood test that can be used to diagnose whether people have cancer or not. [More]
Adopting a comprehensive and integrative healing strategy for cancer

Adopting a comprehensive and integrative healing strategy for cancer

The cancer drugs, radiation therapy and cancer surgery available today help millions of people survive their cancer. [More]
Vanderbilt-led research team identifies protein "signatures" that drive colorectal cancer

Vanderbilt-led research team identifies protein "signatures" that drive colorectal cancer

A Vanderbilt University-led research team has identified protein "signatures" of genetic mutations that drive colorectal cancer, the nation's second leading cause of cancer deaths after lung cancer. [More]