Cytoskeleton News and Research

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Prostate cancer cells gain unnatural ability to change shape and spread

Johns Hopkins Kimmel Cancer Center scientists report they have discovered a biochemical process that gives prostate cancer cells the almost unnatural ability to change their shape, squeeze into other organs and take root in other parts of the body.

8 Aug 2017

Boise State professors win $37,000 grant from NASA to study impact of bone loss in space

Our slim body of knowledge of the universe is vastly overshadowed by what we do not know – whether there is sentient life on other planets, whether there are other planets that can sustain human life, even how long-term space travel physically affects human beings.

31 Jul 2017

DKFZ scientists reveal how cancer cells suppress immune system to spread and multiply

The degenerated cells cause an inflammatory reaction and influence other blood cells with it so much, that the immune system is suppressed.

28 Jul 2017

Penn Medicine professor receives Outstanding Early Career Investigator Award from AHA

Benjamin L. Prosser, PhD, an assistant professor of Physiology, in the Perelman School of Medicine at the University of Pennsylvania, has received the Outstanding Early Career Investigator Award from the American Heart Association's Council on Basic Cardiovascular Sciences, one of its scientific divisions.

25 Jul 2017

Scientists find single protein that controls genes essential for spermatogenesis

Scientists have found a single protein--Ptbp2--controls a network of over 200 genes central to how developing sperm move and communicate. The protein works by regulating how RNA is processed during each stage of sperm development.

10 Jul 2017

Neonatal inflammatory pain may contribute to increased food consumption, obesity in females

Inflammatory pain at birth changes how the hippocampus, a part of the brain associated with memory and eating behavior, works later in life, and this pain also causes adult rats to eat more frequently and in larger amounts, according to a study by Georgia State University and the Charlie Norwood VA Medical Center.

6 Jul 2017

Pathogen linked to seafood poisoning disarms key host defense system by paralyzing cell's skeleton

The leading cause of acute gastroenteritis linked to eating raw seafood disarms a key host defense system in a novel way: It paralyzes a cell's skeleton, or cytoskeleton.

23 Jun 2017

Neurofilaments can help in ALS diagnosis

Researchers at VIB, KU Leuven, and UZ Leuven, in collaboration with researchers at the University of Jena, have demonstrated that measuring neurofilaments provides reliable confirmation of an ALS diagnosis.

19 Jun 2017

Rice scientists use magnets and nanoparticles to make vessels temporarily ‘leaky’

The endothelial cells that line blood vessels are packed tightly to keep blood inside and flowing, but scientists at Rice University and their colleagues have discovered it may be possible to selectively open gaps in those barriers just enough to let large molecules through -- and then close them again.

8 Jun 2017

Researchers discover how tau disrupts functioning of nerve cells even before forming tangles

Tau proteins are involved in more than twenty neurodegenerative diseases, including various forms of dementia.

19 May 2017

Breast cancer cells undergo stiffening state prior to becoming malignant, study shows

A study published now on Nature Communications shows that breast cancer cells undergo a stiffening state prior to acquiring malignant features and becoming invasive.

16 May 2017

Chemical stimuli by small molecule can improve production of cartilage cells

Cell-based therapies could offer a way to treat cartilage injuries before the ultimate damage of osteoarthritis on articular cartilage.

11 May 2017

Scientists identify RIOK1 enzyme as new target for cancer therapy

Dr. Florian Weinberg, from Prof. Dr. Tilman Brummer's research group at the Institute of Molecular Medicine and Cell Research of the University of Freiburg, joined forces with scientists from the Departments of Clinical Pathology and Medicine I of the University Medical Centre Freiburg and the Kinghorn Cancer Centre/Garvan Insitute in Australia in an international team that has identified a new target for cancer therapy.

5 May 2017

New research sheds light on movement of white blood cells to sites of infection

One of the mysteries of the living body is the movement of cells - not just in the blood, but through cellular and other barriers.

10 Apr 2017

German scientists design molecular paintbrush technique to control and monitor key intracellular processes

The plasma membrane serves as a major hub for signal cascades to control crucial cellular processes. But it is a fluid medium, which makes the signaling processes difficult to monitor.

31 Mar 2017

New discovery opens new therapeutic opportunities for treatment of cancer and tissue fibrosis

Researchers from the Turku Centre for Biotechnology (BTK) in Finland have discovered that a cellular fuel sensor, known to control energy processes in the cells, is involved in the regulation of the contact of cells with their surrounding environment.

29 Mar 2017

Study sheds light on cellular mechanisms that enable prostate cancer cells to form secondary tumours

New King's College London research sheds light on the cellular mechanisms which enable cancer cells to escape the prostate and spread to other parts of the body.

20 Mar 2017

UEA study identifies protein essential for healthy development of gut cells

Scientists have uncovered key processes in the healthy development of cells which line the human gut, furthering their understanding about the development of cancer.

8 Feb 2017

PERK protein could be target for development of new drugs for progressive supranuclear palsy

The brain disease "progressive supranuclear palsy" (PSP) is currently incurable and its symptoms can only be eased to a very limited degree. PSP impairs eye movements, locomotion, balance control, and speech.

6 Feb 2017

Researchers identify new mechanism that protects from bacterial infections

An international team led by the University if Barcelona has identified a new antibacterial mechanism that protects macrophages - defense cells in the immune system- from the infection of the bacteria Salmonella enterica serovar Typhimurium, a pathogen associated with several gastrointestinal diseases.

2 Feb 2017