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Delirium is a mental state in which a person is confused, disoriented, and not able to think or remember clearly. The person may also be agitated and have hallucinations, and extreme excitement.
Survey finds low awareness about risks of cognitive side effects following surgery

Survey finds low awareness about risks of cognitive side effects following surgery

Postsurgical cognitive side effects can have major implications for the level of care, length of hospital stay, and the patient's perceived quality of care, especially in elderly and fragile patients. A nationwide survey of Swedish anesthesiologists and nurse anesthetists has found there is low awareness of the risks of cognitive side effects following surgery. [More]
Anti-cholinergic drugs could be responsible for decline in cognitive, physical function in elderly patients

Anti-cholinergic drugs could be responsible for decline in cognitive, physical function in elderly patients

Drugs widely prescribed to the elderly could be responsible for a decline in cognitive and physical function according to research from the University of East Anglia and the Regenstrief Institute. [More]
Stimulating specific brain pathway may induce active emergence from anesthesia

Stimulating specific brain pathway may induce active emergence from anesthesia

Researchers may be one step closer to better understanding how anesthesia works. A study in the August issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists- (ASA-), found stimulating a major dopamine-producing region in the brain, the ventral tegmental area (VTA), caused rats to wake from general anesthesia, suggesting that this region plays a key role in restoring consciousness after general anesthesia. [More]
DBS improves motor and non motor symptoms of patients with early Parkinson's disease

DBS improves motor and non motor symptoms of patients with early Parkinson's disease

Deep brain stimulation (DBS) has become a well-recognized non-pharmacologic treatment that improves motor symptoms of patients with early and advanced Parkinson's disease. [More]
Two Regenstrief investigators receives Career Development K23 Awards from NIH

Two Regenstrief investigators receives Career Development K23 Awards from NIH

Two Regenstrief Institute investigators and Indiana University Center for Aging Research scientists -- Michael LaMantia, M.D., MPH, and Noll L. Campbell, PharmD -- have each received five-year Mentored Patient-Oriented Research Career Development K23 Awards from the National Institute on Aging at the National Institutes of Health. [More]
Critically ill patients receiving steroids in ICU are more likely to develop delirium

Critically ill patients receiving steroids in ICU are more likely to develop delirium

New Johns Hopkins research suggests that critically ill patients receiving steroids in a hospital’s intensive care unit (ICU) are significantly more likely to develop delirium. Results of their research, they say, suggest minimizing the use of steroids could reduce delirium in the ICU. [More]
New understanding of toxicity levels of chemotherapy regimens used for early stage breast cancer

New understanding of toxicity levels of chemotherapy regimens used for early stage breast cancer

Oncologists now have a new understanding of the toxicity levels of specific chemotherapy regimens used for women with early stage breast cancer, according to research from The University of Texas MD Anderson Cancer Center. [More]
Patients receiving steroids in hospital's ICU more likely to develop delirium, says study

Patients receiving steroids in hospital's ICU more likely to develop delirium, says study

New Johns Hopkins research suggests that critically ill patients receiving steroids in a hospital's intensive care unit (ICU) are significantly more likely to develop delirium. Results of their research, they say, suggest minimizing the use of steroids could reduce delirium in the ICU. [More]
Norwegian Accident and Emergency departments not designed for elderly patients

Norwegian Accident and Emergency departments not designed for elderly patients

Norwegian Accident and Emergency departments are not designed for elderly patients, and their staff often lack geriatric experience. [More]
Patients with chronic pulmonary thromboembolic disease may benefit from PTE

Patients with chronic pulmonary thromboembolic disease may benefit from PTE

Patients with chronic pulmonary thromboembolic disease may benefit from pulmonary thromboendarterectomy (PTE), even if the patients don't have severe pulmonary hypertension, according to University of California, San Diego, researchers. [More]
New intervention program may benefit chronically homeless, alcohol-dependent individuals

New intervention program may benefit chronically homeless, alcohol-dependent individuals

Chronically homeless, alcohol-dependent individuals might benefit from a new intervention that does not require them to stop or even reduce drinking, according to the results of a preliminary study in Seattle. [More]
Study: Depression affects more than one out of three critical care survivors

Study: Depression affects more than one out of three critical care survivors

Depression affects more than one out of three survivors of critical illness, according to a Vanderbilt study released in The Lancet Respiratory Medicine, and the majority of patients experience their symptoms physically rather than mentally. [More]
Clot-busting tPA therapy for ischemic stroke patients can avoid lengthy, restrictive monitoring in ICU

Clot-busting tPA therapy for ischemic stroke patients can avoid lengthy, restrictive monitoring in ICU

A Johns Hopkins study of patients with ischemic stroke suggests that many of those who receive prompt hospital treatment with "clot-busting" tissue plasminogen activator (tPA) therapy can avoid lengthy, restrictive monitoring in an intensive care unit (ICU). [More]
Nearly half of hospitalized American adults age 65 require decision-making assistance

Nearly half of hospitalized American adults age 65 require decision-making assistance

Nearly half of hospitalized American adults age 65 and older require decision-making assistance from family members or other surrogates because the patient is too impaired to make decisions independently, according to a new study from the Regenstrief Institute and the Indiana University Center for Aging Research. [More]
Basic hospice strategies can make last days of dying inpatients more comfortable and dignified

Basic hospice strategies can make last days of dying inpatients more comfortable and dignified

There is much value in training hospital and nursing home staff in the basics of palliative care to make the last days of a dying patient's life as comfortable and dignified as possible. [More]
Continued use of statins may help prevent delirium in critically ill patients

Continued use of statins may help prevent delirium in critically ill patients

Continued use of statins may help prevent delirium in critically ill patients who received statins before hospital admission, according to a new study of 470 intensive care patients in the UK. [More]
Researchers identify first biomarker that appears to be associated with duration of delirium

Researchers identify first biomarker that appears to be associated with duration of delirium

Researchers from the Regenstrief Institute and the Indiana University Center for Aging Research have identified the first biomarker that appears to be linked to the duration of delirium. [More]
Genetically engineered cell therapies demonstrate early efficacy, safety in patients with blood disorders

Genetically engineered cell therapies demonstrate early efficacy, safety in patients with blood disorders

A series of advancements in genetically engineered cell therapies demonstrate early efficacy and safety in patients with blood disorders for whom standard treatments have been unsuccessful, according to data showcased today during the 55th American Society of Hematology (ASH) Annual Meeting and Exposition in New Orleans. [More]
Nurse-led initiatives in Indiana improve patient outcomes

Nurse-led initiatives in Indiana improve patient outcomes

Nurse-led initiatives in Indiana measurably improved patient outcomes while demonstrating anticipated financial savings of more than $5.2 million to their organizations, according to initial results from a hospital-based nurse leadership and innovation training program launched last year by the American Association of Critical-Care Nurses. [More]
Senior patients with traumatic injuries can benefit from geriatric care

Senior patients with traumatic injuries can benefit from geriatric care

Older patients who received extra geriatric care following a traumatic injury were able to return to roughly two thirds more daily activities than those without a consultation, according to a new study led by researchers from the University of Michigan Health System and University of California, Los Angeles. [More]