Dermatomyositis News and Research

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Dermatomyositis is one of a group of muscle diseases known as the inflammatory myopathies, which are characterized by chronic muscle inflammation accompanied by muscle weakness.Dermatomyositis’ cardinal symptom is a skin rash that precedes or accompanies progressive muscle weakness. The rash looks patchy, with bluish-purple or red discolorations, and characteristically develops on the eyelids and on muscles used to extend or straighten joints, including knuckles, elbows, heels, and toes. Red rashes may also occur on the face, neck, shoulders, upper chest, back, and other locations, and there may be swelling in the affected areas. The rash sometimes occurs without obvious muscle involvement. Adults with dermatomyositis may experience weight loss or a low-grade fever, have inflamed lungs, and be sensitive to light. Children and adults with dermatomyositis may develop calcium deposits, which appear as hard bumps under the skin or in the muscle (called calcinosis). Calcinosis most often occurs 1-3 years after the disease begins. These deposits are seen more often in children with dermatomyositis than in adults. In some cases of dermatomyositis, distal muscles (muscles located away from the trunk of the body, such as those in the forearms and around the ankles and wrists) may be affected as the disease progresses. Dermatomyositis may be associated with collagen-vascular or autoimmune diseases, such as lupus.
Researchers develop ultrasensitive method to detect protein involved in autoimmune diseases

Researchers develop ultrasensitive method to detect protein involved in autoimmune diseases

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Health care resource use and costs of H.P. Acthar® gel for multiple sclerosis relapse

Anti-TNF therapy offers new hope to JDM patients

Anti-TNF therapy offers new hope to JDM patients

African-American patients with connective tissue diseases at risk for cardiovascular disease

African-American patients with connective tissue diseases at risk for cardiovascular disease

Idera begins enrollment in IMO-8400 Phase 2 clinical trial for treatment of dermatomyositis

Idera begins enrollment in IMO-8400 Phase 2 clinical trial for treatment of dermatomyositis

Clinical study data on Mallinckrodt's H.P. Acthar Gel to be presented at ACR 2015

Clinical study data on Mallinckrodt's H.P. Acthar Gel to be presented at ACR 2015

Former all-American wrestler speaks about his personal battle with chronic muscle disease

Former all-American wrestler speaks about his personal battle with chronic muscle disease

Researchers identify link between autoimmune diseases, medications and Long QT syndrome

Researchers identify link between autoimmune diseases, medications and Long QT syndrome

Idera collaborates with TMA to advance new potential treatment approach for myositis

Idera collaborates with TMA to advance new potential treatment approach for myositis

Baylor receives $3.3M grant from NIAMS to advance research in autoimmune diseases

Baylor receives $3.3M grant from NIAMS to advance research in autoimmune diseases

Idera Pharmaceuticals reports positive top-line results from Phase 2 trial of IMO-8400

Idera Pharmaceuticals reports positive top-line results from Phase 2 trial of IMO-8400

Researchers create specific tests to detect cancer biomarkers in patients with dermatomyositis

Researchers create specific tests to detect cancer biomarkers in patients with dermatomyositis

Questcor acquires rights to develop Synacthen and Synacthen Depot in US

Questcor acquires rights to develop Synacthen and Synacthen Depot in US

Age at onset influences juvenile dermatomyositis course

Age at onset influences juvenile dermatomyositis course

Questcor second quarter net sales increase to $112.5 million

Questcor second quarter net sales increase to $112.5 million

Intravenous immune globulin effective treatment for GBS, CIDP

Intravenous immune globulin effective treatment for GBS, CIDP

Questcor fourth quarter net sales increase to $75.5 million

Questcor fourth quarter net sales increase to $75.5 million

Most autoimmune diseases associated with increased risk of blood clots on the lung

Most autoimmune diseases associated with increased risk of blood clots on the lung

Positive results from etanercept pilot study against dermatomyositis

Positive results from etanercept pilot study against dermatomyositis

Amylin's metreleptin clinical study data on partial lipodystrophy presented at ENDO 2011

Amylin's metreleptin clinical study data on partial lipodystrophy presented at ENDO 2011