Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Wayne State professor wins $2.65 million NIH award to develop novel filtration platform for insulin administration

A Wayne State University College of Engineering professor has received a $2.65 million award from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health to develop a novel filtration platform to improve an advanced drug delivery device to optimize diabetes insulin treatments.

28 Nov 2023

Radiation therapy could improve cardiac function in heart failure

Cardiologists and radiation oncologists at Washington University School of Medicine in St. Louis pioneered the use of radiation therapy -; a strategy typically used against cancer -; to treat patients with a life-threatening abnormal heart rhythm called ventricular tachycardia.

28 Nov 2023

Synthetic biologists develop versatile platform for targeted drug delivery

In recent years, cell and gene therapies have shown significant promise for treating cancer, cystic fibrosis, diabetes, heart disease, HIV/AIDS and other difficult-to-treat diseases.

27 Nov 2023

Feasting for immunity: Study highlights foods that bolster your body's defenses

Study reviews how certain foods, including fruits, vegetables, spices, and animal products, bolster the immune system. It details the immune-boosting properties of various foods and underscores the importance of a nutritious diet in disease prevention and management.

26 Nov 2023

Study identifies key markers for early detection of fatty liver disease in obese and non-obese individuals

In a study published in 'Scientific Reports', researchers found that insulin resistance markers TyG-BMI and HOMA-IR effectively predict non-alcoholic fatty liver disease (NAFLD) risks in non-obese and obese individuals without diabetes, respectively. These findings suggest new, non-invasive methods for early NAFLD detection, particularly in atypical non-obese cases.

26 Nov 2023

Scientists create living phlegm replica to study cystic fibrosis infections

Scientists have engineered a living material resembling human phlegm, which will help them to better understand how a certain kind of infection develops on the lungs of patients with cystic fibrosis.

21 Nov 2023

Pitt researcher receives $1.95 million grant to study cell communication

Day by day, we communicate with our office colleagues to accomplish tasks that are necessary to function.

21 Nov 2023

Amalus Therapeutics develops innovative approach for treating patients with cancer or fibrotic diseases

Ghent University and the booming Ghent biotech landscape welcome a brand new spin-off: Amalus Therapeutics is developing a new class of drugs that selectively target corrupt fibroblast cells.

20 Nov 2023

MHRA extends the license of two cystic fibrosis drugs for children aged two to five years old

The Medicines and Healthcare products Regulatory Agency (MHRA) has today (15 November 2023) extended the licence of the cystic fibrosis medicines Kaftrio (ivacaftor, tezacaftor and elexacaftor) and Kalydeco (ivacaftor) for children aged two to five years old.

20 Nov 2023

Intestinal hormones hold promise for halting liver scarring

Hormone therapy may be associated with menopause and fertility treatment, but now an SDU-led research team reports that certain intestinal hormones seem to have a beneficial effect on the processes behind the formation of scar tissue in the liver (liver fibrosis).

16 Nov 2023

Researchers discover genetic mechanism behind pancreatic cancer metastasis

Pancreatic cancer is tricky to manage because it spreads easily and early, and the tumors have a unique biological makeup.

15 Nov 2023

COVID-19 triggers epigenetic alterations that drive lung damage and fatalities

The COVID-19 disease, due to infection with the SARS-CoV2 virus, became an international pandemic in 2020. To date, more than 770 million people have suffered from the disease and nearly 7 million of them have lost their life.

14 Nov 2023

Is obesity an independent risk factor for cardiovascular disease?

Researchers explore how obesity contributes to cardiovascular disease by investigating this association in low-risk people.

10 Nov 2023

New insights into the pathogenesis of chronic liver diseases

Fatty liver diseases (FLD) have become a significant health concern worldwide, affecting millions. The two most common types of FLD are non-alcoholic fatty liver disease (NAFLD) and alcoholic-associated liver disease (ALD). NAFLD is associated with obesity, insulin resistance, and metabolic syndrome, while ALD is caused by excessive alcohol consumption.

7 Nov 2023

Surgeons to get a high-tech assistant: Smartphone app for assessing liver surgery risks

Researchers developed a multivariable model to predict clinically relevant posthepatectomy liver failure grade B and C, grade C, and 90-day mortality prediction.

6 Nov 2023

States reconsider religious exemptions for vaccinations in child care

More than half the children who attend Munchkin Land Daycare near Billings, Montana, have special needs or compromised immune systems.

3 Nov 2023

Shark skin mucus shows potential for biomedical applications

Sharks differ from other fish in many ways, including an apparently remarkable ability to heal from wounds, according to reports of sharks recovering from injuries sustained in the wild.

2 Nov 2023

Unbiased proteomic analysis reveals fibroinflammatory landscape of the aging ovary

A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 20, entitled, "Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature."

31 Oct 2023

From Mount Everest to your liver: The alarming reach of 'forever chemicals' in our environment and health

Research paper provides a comprehensive review of per- and polyfluoroalkyl substances (PFAS), exploring their environmental prevalence, human exposure risks, and liver toxicity. The study highlights urgent gaps in PFAS research and calls for more studies to better understand these 'forever chemicals' and their impact on human health.

26 Oct 2023

Researchers identify mechanism through which dietary omega 3 supplements alleviate liver condition

A study spearheaded by Oregon State University has shown why certain polyunsaturated fatty acids work to combat a dangerous liver condition, opening a new avenue of drug research for a disease that currently has no FDA-approved medications.

25 Oct 2023