Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Eating ultra-processed foods puts your liver at risk, new study warns

Research found a significant link between the consumption of ultra-processed foods (UPFs) and increased risks of non-alcoholic fatty liver disease, liver cirrhosis, and severe hepatic illnesses. The findings suggest that reducing UPF intake could be key to enhancing liver health and well-being.

25 Oct 2023

Red grape polyphenol, resveratrol: a multifaceted therapeutic powerhouse under review

The therapeutic potential of resveratrol, a red grape polyphenol.

25 Oct 2023

Study reveals unexpected role of pulmonary ionocytes in lung function

A new study by University of Iowa researchers finds that rare lung cells known as pulmonary ionocytes facilitate the absorption of water and salt from the airway surface.

24 Oct 2023

Pioneering partnership supports early-stage innovation against antimicrobial resistance to save lives

Innovate UK, LifeArc, and Medicines Discovery Catapult (MDC) have joined forces to create PACE (Pathways to Antimicrobial Clinical Efficacy), a £30 million initiative supporting early-stage innovation against antimicrobial resistance (AMR) to save lives. PACE has today (19 October 2023) announced its first funding call with up to £10 million available to support innovators developing new antimicrobials.

20 Oct 2023

Major study wins €5.6M funding to build a better understanding of cystic fibrosis in children

A major new study led by RCSI University of Medicine and Health Sciences and Children's Health Ireland (CHI) has been awarded funding of €5.6M to work with babies and children in Ireland and the UK over the next five years to build a better understanding of cystic fibrosis.

18 Oct 2023

Lung chip model offers new insights into how radiation damages the lungs

The lung is one of the tissues most sensitive to radiation in the human body. People exposed to high radiation doses following nuclear incidents develop radiation-induced lung injury (RILI), which affects the function of many cell types in the lung, causing acute and sustained inflammation, and in the longer term, the thickening and scarring of lung tissue known as fibrosis.

17 Oct 2023

Insilico Medicine to present scientific data on novel anti-cancer assets at major cancer conferences

Clinical stage artificial intelligence (AI) drug discovery company Insilico Medicine ("Insilico") has been invited to present scientific data on its novel anti-cancer assets at three major upcoming cancer conferences -- the European Society for Medical Oncology (ESMO) conference in Madrid Oct. 20-24, 2023; the Society of Immunotherapy of Cancer (SITC) conference Nov. 1-5, 2023 in San Diego; and the San Antonio Breast Cancer Symposium (SABCS) Dec. 5-9, 2023.

16 Oct 2023

Study discovers link between birthweight and onset of nonalcoholic fatty liver disease in young people

A groundbreaking new study, presented today at UEG Week 2023, has discovered a significant connection between birthweight and the onset of nonalcoholic fatty liver disease, now known as metabolic dysfunction-associated steatotic liver disease (MASLD), in young people.

15 Oct 2023

Long-term lung issues and lower quality of life plague COVID-19 survivors, new study warns

New research in Scientific Reports reveals that COVID-19 survivors, especially those who had severe or critical illness, face long-term lung complications and a reduced quality of life. The study recommends 6-monthly pulmonary function tests for these survivors to monitor for chronic lung damage.

15 Oct 2023

New animal model replicates the development of cardiac sarcoidosis

Sarcoidosis is an inflammatory disease in which immune cells form tissue nodules in various organs, which can drastically impair organ function.

5 Oct 2023

The adipose tissue dysfunction behind metabolically healthy obesity

A session at this year's Annual Meeting of the European Association for the Study of Diabetes will explore the latest data on the concept of metabolically healthy obesity (MHO) – more commonly known by the public as 'fat but fit'.

4 Oct 2023

New analytical tool could lead to a cure for idiopathic pulmonary fibrosis

Using a new recipe for growing blood vessels from living lung tissue in the lab, a University of Virginia School of Engineering and Applied Science research team has developed an analytical tool that could lead to a cure for idiopathic pulmonary fibrosis, or IPF, a lung-destroying disease.

3 Oct 2023

Monocyte-derived macrophages play a crucial role in liver regeneration

The liver is a vital organ that plays a role in many essential functions, including digestion, detoxification, and metabolism.

29 Sep 2023

Researchers describe the origin and fate of liver myofibroblasts

Hepatic fibrosis occurs when scar tissue replaces damaged cells in the liver. Over time, accumulating scarring distorts the liver, interferes with its blood supply and may progressively lead to worsening consequences, from cirrhosis to liver failure to liver cancer.

28 Sep 2023

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

Two nationally recognized experts in cloning and stem cell science from the University of Houston, Wa Xian and Frank McKeon, are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic fibrosis (CF), and that these variants drive key aspects of CF pathology including inflammation, fibrosis and mucin secretion.

28 Sep 2023

Study uncovers previously unknown compensatory mechanism in liver disease

A team of researchers has uncovered a previously unknown compensatory mechanism found in liver disease.

28 Sep 2023

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Researchers pursued evidence of whether the interaction between the patatin-like phospholipase domain-containing 3 p.I148M variant and the female sex at the genetic and molecular level explains why premenopausal women remain protected against fatty liver disease, while a rapidly progressive disease ensues in some peri- and postmenopausal women.

28 Sep 2023

Examining the cardiac pathology in fatal cases of yellow fever

The characteristics of yellow fever (YF)-related myocardial damage.

28 Sep 2023

$10.2M NIH grant awarded to study risk factors for malignant arrhythmias in mitral valve prolapse

Researchers at the Icahn School of Medicine at Mount Sinai have been awarded a $10.2 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to investigate risk factors for malignant arrhythmias in mitral valve prolapse.

26 Sep 2023

COVID drug molnupiravir appears to be driving SARS-CoV-2 to mutate and evolve

Molnupiravir, an antiviral drug used to treat patients with COVID-19, appears to be driving SARS-CoV-2 to mutate and evolve, with some of these new viruses being transmitted onwards, a new study has shown. It is not clear, however, whether these mutated viruses pose an increased risk to patients or are able to evade the vaccine.

25 Sep 2023

Fibrosis News and Research

Further Reading

Eating ultra-processed foods puts your liver at risk, new study warns

Red grape polyphenol, resveratrol: a multifaceted therapeutic powerhouse under review

Study reveals unexpected role of pulmonary ionocytes in lung function

Pioneering partnership supports early-stage innovation against antimicrobial resistance to save lives

Major study wins €5.6M funding to build a better understanding of cystic fibrosis in children

Lung chip model offers new insights into how radiation damages the lungs

Insilico Medicine to present scientific data on novel anti-cancer assets at major cancer conferences

Study discovers link between birthweight and onset of nonalcoholic fatty liver disease in young people

Long-term lung issues and lower quality of life plague COVID-19 survivors, new study warns

New animal model replicates the development of cardiac sarcoidosis

The adipose tissue dysfunction behind metabolically healthy obesity

New analytical tool could lead to a cure for idiopathic pulmonary fibrosis

Monocyte-derived macrophages play a crucial role in liver regeneration

Researchers describe the origin and fate of liver myofibroblasts

Newly identified stem cell variants drive inflammation in cystic fibrosis patients

Study uncovers previously unknown compensatory mechanism in liver disease

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Examining the cardiac pathology in fatal cases of yellow fever

$10.2M NIH grant awarded to study risk factors for malignant arrhythmias in mitral valve prolapse

COVID drug molnupiravir appears to be driving SARS-CoV-2 to mutate and evolve

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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