Ganglion News and Research

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In anatomy, a ganglion (plural ''ganglia'') is a biological tissue mass, most commonly a mass of nerve cell bodies. Cells found in a ganglion are called ganglion cells, though this term is also sometimes used to refer specifically to retinal ganglion cells.

Cascade aggravates hereditary storage diseases

In rare, hereditary storage diseases such as Sandhoff's disease or Tay-Sachs syndrome, the metabolic waste from accumulating gangliosides cannot be properly disposed of in the nerve cells because important enzymes are missing.

26 Jun 2019

Inhibition of CRMP2 phosphorylation promotes axonal regeneration after optic nerve injury

A new study by Professor Toshio Ohshima of Waseda University has found that the inhibition of phosphorylation of collapsing response mediator protein 2, a microtubule-binding protein, suppresses degeneration of nerve fibers and promotes its regeneration after optic nerve injury.

22 May 2019

Active lifestyles may help damaged nerves to regenerate after spinal cord injury

Leading an active lifestyle may increase the likelihood of damaged nerves regenerating after a spinal cord injury.

10 Apr 2019

Promising diagnostic, prognostic tools for onset and progression of ALS

Amyotrophic lateral sclerosis is a motor neuron disease with rampant progression and that it is typically fatal within 5 years of prognosis.

5 Apr 2019

Study provides new understanding of how the brain recovers from damage caused by stroke

Each year, approximately 265,000 Americans have a stroke that causes visual impairment. New research, which appears in the journal Proceedings of the Royal Society B, sheds light on how the damage in the brain caused by a stroke can lead to permanent vision impairment.

21 Mar 2019

Promising gene therapy could restore vision in humans

It was surprisingly simple. University of California, Berkeley, scientists inserted a gene for a green-light receptor into the eyes of blind mice and, a month later, they were navigating around obstacles as easily as mice with no vision problems.

15 Mar 2019

New therapy could help prolong useful vision and delay total blindness

Millions of Americans are progressively losing their sight as cells in their eyes deteriorate, but a new therapy developed by researchers at the University of California, Berkeley, could help prolong useful vision and delay total blindness.

14 Mar 2019

New cellular atlas could provide a deeper insight into blinding diseases

When it comes to understanding how neurons connect to form circuits in the brain, scientists for decades have turned to the retina of the humble laboratory mouse as an ideal model organism. But as a model for vision and vision-related diseases, mice simply aren't equipped.

22 Feb 2019

New target appears to aid recovery after optic nerve trauma

When a car crash or explosion results in an optic nerve injury, eliminating an enzyme known to promote inflammation appears to aid recovery, scientists report.

11 Feb 2019

How Patch Clamp Technology Can Benefit Ion Channel Research

Learn how patch clamp technology meets high-throughput to benefit ion channel research in this interview with Tim and James, Nanion.

From Nanion Technologies 16 Jan 2019

UC San Diego Health offers new DRG stimulation device for phantom limb pain

In May 2000, Raul Silva was involved in a motorcycle accident in Baja California, Mexico, badly breaking his left femur, or thighbone. He underwent emergency surgery in Mexicali and, at first, everything seemed fine. Then an infection set in, worsened, and Silva eventually made his way to San Diego, where his left leg was amputated.

18 Dec 2018

Botulinum toxin injections show promise to suppress postoperative atrial fibrillation

Postoperative atrial fibrillation is a common complication, affecting one quarter to one half of all patients following cardiac surgery.

28 Nov 2018

Breakthrough technology offers new hope to people with glaucoma, retinitis and macular degeneration

In January 2009, the life of engineer Michel Meunier, a professor at Polytechnique Montréal, changed dramatically. Like others, he had observed that the extremely short pulse of a femtosecond laser (0.000000000000001 second) could make nanometer-sized holes appear in silicon when it was covered by gold nanoparticles.

20 Nov 2018

Scientists identify ancient light-sensing mechanism in modern mouse retinal cells

Scientists at Johns Hopkins Medicine say they have identified what may be an ancient light-sensing mechanism in modern mouse retinal cells.

9 Nov 2018

Lab-created mini retinas allow researchers to understand retinal ganglion cell development

IUPUI biologists are growing 'mini retinas' in the lab from stem cells to mimic the growth of the human retina. The researchers hope to use the research to restore sight when critical connections between the eye and the brain are damaged.

25 Oct 2018

11th World Stroke Congress examines high stroke impact in low- and middle-income countries

11th World Stroke Congress brings together leading international stroke experts and an unparalleled scientific program covering epidemiology, prevention, acute care, recovery and rehabilitation in 100s of sessions and oral posters.

22 Oct 2018

Researchers for the first time differentiate human inner ear cells in laboratory

Researchers from the University of Bern and Bern University Hospital have managed for the first time to differentiate human inner ear cells in a laboratory from somatic progenitors and to investigate their origin.

3 Oct 2018

New night vision mechanism related to motion detected

When lights are dim or absent, animals tend to use their night vision to adjust to the low light and visualize their path and their prey. They need this to escape predators and protecting themselves. The little amounts of photons available are picked up by the eyes to detect what lies in front of them.

14 Sep 2018

Using peripheral nerve blocks to treat facial pain may produce long-term pain relief

A new study has shown that use of peripheral nerve blocks in the treatment of Trigeminal Neuralgia may produce long-term pain relief.

14 Aug 2018

Glaucoma could be an autoimmune disorder, study suggests

Glaucoma, a disease that afflicts nearly 70 million people worldwide, is something of a mystery despite its prevalence. Little is known about the origins of the disease, which damages the retina and optic nerve and can lead to blindness.

10 Aug 2018