Genes News and Research

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Researchers develop new method to identify genes involved in kidney diseases

Understanding how genes act in specific tissues is critical to our ability to combat many human diseases, from heart disease to kidney failure to cancer. Yet isolating individual cell types for study is impossible for most human tissues.

5 Oct 2013

Study identifies new potential genetic culprits in origins of congenital heart defects

Mitochondria are the power plants of cells, manufacturing chemical fuel so a cell can perform its many tasks. These cellular power plants also are well known for their role in ridding the body of old or damaged cells.

5 Oct 2013

Cynvenio launches ClearID Breast Cancer monitoring program

Cynvenio, a cancer diagnostics company focused on transforming cancer treatment and management through the molecular analysis of tumor biomarkers in blood, today launched a new weapon in the fight against breast cancer, the ClearID Breast Cancer monitoring program.

4 Oct 2013

Individuals diagnosed with ASD more likely to have gene deletions, shows analysis

Using powerful genetic sequencing technology, a team of investigators, led by researchers at the Icahn School of Medicine at Mount Sinai, scanned the genome of hundreds of individuals, and discovered those diagnosed with autism spectrum disorder (ASD) were more likely to have gene deletions than were people without the disorder.

4 Oct 2013

CHOP’s 22q and You Center plays major role in brain and behavior consortium

Genetics experts from The Children's Hospital of Philadelphia (CHOP) are among the top leaders of a major international collaboration researching why patients with chromosome 22q11.2 deletion syndrome have an elevated risk of schizophrenia and other psychiatric illnesses.

4 Oct 2013

Genetically modified bacterial treatment approach reduces or eliminates sleeping sickness

A tag team of two bacteria, one of them genetically modified, has a good chance to reduce or even eliminate the deadly disease African trypanosomiasis, or sleeping sickness, researchers at Oregon State University conclude in a recent mathematical modeling study.

4 Oct 2013

Harvard University receives $3.5M grant to develop super-resolution microscopy technique

A team at the Wyss Institute for Biologically Inspired Engineering at Harvard University has been awarded a special $3.5 million grant from the National Institutes of Health (NIH) to develop an inexpensive and easy-to-use new microscopy method to simultaneously spot many tiny components of cells.

4 Oct 2013

Discovery paves way for development of new medicines to combat herpes infections

Researchers at Lund University in Sweden and Carnegie Mellon University have for the first time managed to measure the internal pressure that enables the herpes virus to infect cells in the human body. The discovery paves the way for the development of new medicines to combat viral infections. The results indicate good chances to stop herpes infections in the future.

3 Oct 2013

New method to monitor activity of gene promoters during response to drug

When developing new drugs, monitoring cellular responses to candidate compounds is essential for assessing their efficacy and safety. Researchers from the RIKEN Center for Life Science Technologies report a new method to monitor and quantify the activity of gene promoters during the response to a drug, using the advanced gene expression analysis method CAGE followed by single-molecule sequencing.

3 Oct 2013

Specialized cells play major role in inflammation that underlies Crohn's disease in small intestine

Scientists have discovered that Crohn's disease, the inflammatory bowel disorder, can originate from specialised intestinal cell type called Paneth cells. As such, they propose that small intestinal Crohn's disease might be a specific disorder of this cell type, providing a possible new target for treatments.

3 Oct 2013

Excessive weight gain during pregnancy may have significant effect on future obesity among children

A study of 41,133 mothers and their children in Arkansas shows that high pregnancy weight gain increases the risk of obesity in those children through age 12. The findings, published Oct. 1 in PLoS Medicine by Princeton University, suggest pregnancy may be an especially important time to prevent obesity in the next generation.

3 Oct 2013

Findings may result in better management of chronic depression

Virginia Commonwealth University has received a $3 million grant from the National Institute of Mental Health to study key molecular markers found in DNA that predict chronic depression.

2 Oct 2013

Epigenetic Markers Found For Head And Neck Cancers

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2 Oct 2013

Laboratory testing kit that estimates risk of breast cancer relapse gets FDA approval

A laboratory testing kit that estimates the risk of breast cancer relapse in spite of anti-hormone treatment has received approval from the U.S. Food and Drug Administration.

2 Oct 2013

Genetic discovery could take guesswork out of prescribing correct dose of drugs

The discovery of genetic differences affecting up to a third of the population could take the guesswork out of prescribing the correct dose of 25 percent of drugs currently on the market, researchers say.

2 Oct 2013

Genetic study helps identify obese diabetes patients who are at risk of developing NAFLD

A groundbreaking study of nearly 2,300 extremely obese diabetes patients, led by the Translational Genomics Research Institute, has identified genes associated with unhealthy liver function.

2 Oct 2013

Research findings show how flawed transport gene contributes to autism

Researchers say it's clear that some cases of autism are hereditary, but have struggled to draw direct links between the condition and particular genes. Now a team at the Johns Hopkins University School of Medicine, Tel Aviv University and Technion-Israel Institute of Technology has devised a process for connecting a suspect gene to its function in autism.

1 Oct 2013

Pitt scientists open door to potential research into cures for Parkinson's disease

A mix of serendipity and dogged laboratory work allowed a diverse team of University of Pittsburgh scientists to report in the Oct. 1 issue of Nature Cell Biology that they had solved the mystery of a basic biological function essential to cellular health.

1 Oct 2013

Standoff between a mutated gene and normal counterpart keeps certain cancer cells alive

What keeps leukemia cells alive almost forever, able to continue dividing endlessly and aggressively? New research at the Weizmann Institute suggests that, in around a quarter of all leukemias, the cancer cells rely on an internal "balance of terror" to keep going.

1 Oct 2013

New approaches needed for testing cancer drugs

Research institutes, regulators and the pharmaceutical industry are urged to cooperate to develop new approaches to testing cancer drugs, in order to bring the revolution in personalised medicine to patients across Europe, says the European Society for Medical Oncology.

1 Oct 2013

Genes News and Research

Researchers develop new method to identify genes involved in kidney diseases

Study identifies new potential genetic culprits in origins of congenital heart defects

Cynvenio launches ClearID Breast Cancer monitoring program

Individuals diagnosed with ASD more likely to have gene deletions, shows analysis

CHOP’s 22q and You Center plays major role in brain and behavior consortium

Genetically modified bacterial treatment approach reduces or eliminates sleeping sickness

Harvard University receives $3.5M grant to develop super-resolution microscopy technique

Discovery paves way for development of new medicines to combat herpes infections

New method to monitor activity of gene promoters during response to drug

Specialized cells play major role in inflammation that underlies Crohn's disease in small intestine

Excessive weight gain during pregnancy may have significant effect on future obesity among children

Findings may result in better management of chronic depression

Epigenetic Markers Found For Head And Neck Cancers

Laboratory testing kit that estimates risk of breast cancer relapse gets FDA approval

Genetic discovery could take guesswork out of prescribing correct dose of drugs

Genetic study helps identify obese diabetes patients who are at risk of developing NAFLD

Research findings show how flawed transport gene contributes to autism

Pitt scientists open door to potential research into cures for Parkinson's disease

Standoff between a mutated gene and normal counterpart keeps certain cancer cells alive

New approaches needed for testing cancer drugs

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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