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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.
JAX researchers find precise, reliable way to identify leukemia cells of origin

JAX researchers find precise, reliable way to identify leukemia cells of origin

Every cancer starts with a single cell, and Jackson Laboratory researchers have found a precise and reliable way -- whole-genome profiling of open chromatin -- to identify the kind of cell that leads to a given case of leukemia, a valuable key to cancer prognosis and outcome. [More]
AMP looks forward to working with FDA to determine optimal approach to regulating NGS tests

AMP looks forward to working with FDA to determine optimal approach to regulating NGS tests

The Association for Molecular Pathology, the premier global, non-profit organization serving molecular diagnostic professionals, today announced that it looks forward to working with the U.S. Food and Drug Administration to determine the best adaptive approach to regulating Next-Generation Sequencing (NGS) tests. [More]
New diagnostic blood test may offer hope for transplant recipients through analysis of cfDNA

New diagnostic blood test may offer hope for transplant recipients through analysis of cfDNA

When cells die, whether through apoptosis or necrosis, the DNA and other molecules found in those cells don't just disappear. They wind up in the blood stream, where degraded bits and pieces can be extracted. [More]
Germline genetic testing necessary for men with metastatic prostate cancer

Germline genetic testing necessary for men with metastatic prostate cancer

Men with metastatic prostate cancer should be considered for germline genetic testing of DNA repair genes, regardless of age or family history, according to a team of researchers from Memorial Sloan Kettering Cancer Center, Fred Hutchinson Cancer Research Center, Dana-Farber Cancer Institute, University of Washington School of Medicine, University of Michigan, and the Institute of Cancer Research Royal Marsden Hospital. [More]
Study results pave way to development of effective human vaccine against HIV

Study results pave way to development of effective human vaccine against HIV

A new scientific study conducted by a team of leading AIDS scientists reveal results that lead the way to the development of an effective human vaccine against human immunodeficiency virus (HIV). [More]
TSRI awarded $20 million for first year of precision medicine initiative cohort program

TSRI awarded $20 million for first year of precision medicine initiative cohort program

As part of the most ambitious medical research program in the history of American medicine, The Scripps Research Institute (TSRI) has received an initial award of $20 million for its role in a national precision medicine initiative, the National Institutes of Health (NIH) announced today. [More]
Buck researchers find new way for possible treatment of AMD

Buck researchers find new way for possible treatment of AMD

Buck researchers boosted the potency of a broccoli-related compound by ten times and identified it as a possible treatment for age-related macular degeneration (AMD), the leading cause of vision loss affecting more than 10 million older Americans. [More]
Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Diabetes drug metformin could help reduce toxic acid levels linked to MSUD

Maple Syrup Urine Disease (MSUD) is a rare inherited metabolic disorder involving the dysfunction of an enzyme which breaks down three essential amino acids: leucine, isoleucine and valine. [More]
Quantum Genomics initiates Phase IIa trial for heart failure

Quantum Genomics initiates Phase IIa trial for heart failure

Quantum Genomics, a biopharmaceutical company with the mission of developing new therapies for unmet medical needs in the field of cardiovascular diseases, today announced the initiation of its Phase IIa multicentric clinical trial of GQC101, entitled QUID HF (QUantum Genomics Incremental Dosing in Heart Failure), for the treatment of patients with chronic heart failure. The first three clinical centres of the European trial have been opened in France and Norway. [More]
Researchers discover human factor that drives maturation of helper T cells

Researchers discover human factor that drives maturation of helper T cells

A powerful arm of the immune system is production of antibodies that circulate through the blood and neutralize invading pathogens. Although B cells actually manufacture antibody proteins, the process is aided by neighboring T cells, which shower B cells with cytokines to make them churn out high-quality antibody proteins--and remember how to do so. [More]
Study shows how genetic variants control immune cell response to pathogens

Study shows how genetic variants control immune cell response to pathogens

A study that is first in its kind and published in Nature Medicine today has looked at how far genetic factors control the immune cell response to pathogens in healthy individuals. [More]
Recommendations for integrating genomic results into clinical practice

Recommendations for integrating genomic results into clinical practice

A quiet transformation has been brewing in medicine, as large-scale DNA results become increasingly available to patients and healthcare providers. [More]
CVD researchers to use minimally invasive tissue sampling to identify cause of child mortality

CVD researchers to use minimally invasive tissue sampling to identify cause of child mortality

The Center for Vaccine Development has been awarded a large grant for research that will help determine why so many children under five are dying in the world's poorest countries. [More]
Breakthrough research could lead to new drugs to improve heart attack outcomes

Breakthrough research could lead to new drugs to improve heart attack outcomes

A research advance from the Sanford Burnham Prebys Medical Discovery Institute and Stanford University could lead to new drugs that minimize the damage caused by heart attacks. [More]
New technology could help deliver treatments for brain injuries

New technology could help deliver treatments for brain injuries

A new study led by scientists at the Sanford Burnham Prebys Medical Discovery Institute describes a technology that could lead to new therapeutics for traumatic brain injuries. The discovery, published today in Nature Communications, provides a means of homing drugs or nanoparticles to injured areas of the brain. [More]
TSRI scientists develop new strategy to design potential HIV vaccine candidates

TSRI scientists develop new strategy to design potential HIV vaccine candidates

Want to catch a criminal? Show a mugshot on the news. Want to stop HIV infections? Get the immune system to recognize and attack the virus's tell-tale structure. That's part of the basic approach behind efforts at The Scripps Research Institute to design an AIDS vaccine. [More]
Scientists create protein signatures for accurate diagnosis of prostate cancer

Scientists create protein signatures for accurate diagnosis of prostate cancer

Researchers at the Ontario Institute for Cancer Research and University Health Network in Toronto, along with researchers at the Eastern Virginia Medical School, have created protein signatures that accurately diagnose prostate cancer and can distinguish between patients with aggressive versus non-aggressive disease using a simple urine sample. [More]
Scientists develop computational method to map cancer progression

Scientists develop computational method to map cancer progression

A team of scientists has developed a computational method to map cancer progression, an advance that offers new insights into the factors that spur this affliction as well as new ways of selecting effective therapies. [More]
RepeatAnalyzer improves scientists' ability to identify, manage bacterial strains

RepeatAnalyzer improves scientists' ability to identify, manage bacterial strains

Washington State University researchers have developed a new software tool that will improve scientists' ability to identify and understand bacterial strains and accelerate vaccine development. [More]
Advances in epigenome sequencing technologies can allow comprehensive analysis of cancers

Advances in epigenome sequencing technologies can allow comprehensive analysis of cancers

An international research collaboration led by UCL scientists has developed ways to improve the quality and accuracy of information harvested from epigenome sequencing datasets in two new research papers published jointly in Nature Biotechnology and Nature Communications today. According to the studies, epigenome sequencing technologies can allow for more comprehensive analysis of cancers - a key component in the development of targeted approaches to combat cancer. [More]
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