Gout News and Research

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Gout is a type of arthritis that causes painful inflammation in the joints. Usually it affects one joint which is most commonly the big toe. However, it can affect any joint in the body such as the ankles, knees, wrists, elbows and any joints in the hands or finger.

Symptoms of gout usually develop rapidly and usually start at night. The joint may then start to feel normal again with any pain or discomfort eventually disappearing . However, most people who get gout will have further attacks in the future.

The symptoms of gout are caused by an above normal level of urate in the bloodstream, which builds up and forms crystals, mainly in and around joints and especially in the finger and toe joints. This can lead to intensely pain and inflammation.

There are several factors that can increase the level of blood urate. These include a diet rich in purines (which form urate when broken down) such as red meat, seafood and some other foods; excess alcohol consumption; the use of certain medicines such as diuretics; a family history of gout; kidney disease; and overweight or obesity.

Gout affects about 1% of the population and is more common in men, particularly those aged 30 to 60, and in women who have already experienced the menopause.
Positive interim results from TWIB's AC-201 CR Phase 2 study for hyperuricemia and gout

Positive interim results from TWIB's AC-201 CR Phase 2 study for hyperuricemia and gout

Zurampic (lesinurad) approved to treat high levels of hyperuricemia associated with gout

Zurampic (lesinurad) approved to treat high levels of hyperuricemia associated with gout

NEK7 enzyme acts as on-off switch in innate immune system

NEK7 enzyme acts as on-off switch in innate immune system

Presence of tophi in people with gout can increase risk of developing cardiovascular disease

Presence of tophi in people with gout can increase risk of developing cardiovascular disease

Sleep apnea may increase gout risk

Sleep apnea may increase gout risk

Experts and researchers develop new classification criteria for gout

Experts and researchers develop new classification criteria for gout

UT Southwestern evaluates allopurinol drug to prevent nephropathy in Type I diabetes patients

UT Southwestern evaluates allopurinol drug to prevent nephropathy in Type I diabetes patients

ACR releases two new publications to improve treatment of polymyalgia rheumatica, gout

ACR releases two new publications to improve treatment of polymyalgia rheumatica, gout

ESC publishes new guidelines on pericardial diseases

ESC publishes new guidelines on pericardial diseases

University of Otago research backs the belief that eating tomatoes can cause gout to flare up

University of Otago research backs the belief that eating tomatoes can cause gout to flare up

TWi Biotechnology gets notice of patent allowance covering use of AC-201 drug in diabetes treatment

TWi Biotechnology gets notice of patent allowance covering use of AC-201 drug in diabetes treatment

Common gout medications may offer protection from alcohol-induced liver disease, inflammation

Common gout medications may offer protection from alcohol-induced liver disease, inflammation

3SBio purchases entire equity interest in Zhejiang Wansheng

3SBio purchases entire equity interest in Zhejiang Wansheng

Fructose stimulates reward system in the brain to a lesser degree than glucose

Fructose stimulates reward system in the brain to a lesser degree than glucose

3SBio obtains ex-China global rights to Apexigen's anti-TNF mAb technology

3SBio obtains ex-China global rights to Apexigen's anti-TNF mAb technology

Fewer patients take effective gout drug after steep price increase

Fewer patients take effective gout drug after steep price increase

Arthritis & Osteoporosis NSW to hold Clinical Update for 2015 for health professionals

Arthritis & Osteoporosis NSW to hold Clinical Update for 2015 for health professionals

TWi Biotechnology obtains Rare Disease Drug designation in Taiwan for use of AC-203 to treat EBS

TWi Biotechnology obtains Rare Disease Drug designation in Taiwan for use of AC-203 to treat EBS

Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

Trinity scientists reveal new marvel molecule that can block key process in inflammatory diseases

3SBio, PharmAbcine sign licensing agreement to develop and market DIG-KT

3SBio, PharmAbcine sign licensing agreement to develop and market DIG-KT