Hippocampus News and Research

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The hippocampus is a part of the forebrain, located in the medial temporal lobe. It belongs to the limbic system and plays major roles in short term memory and spatial navigation. Humans and other mammals have two hippocampi, one in each side of the brain.

Glutamate imaging may guide surgery in ‘nonlesional’ epilepsy

Glutamate imaging may be capable of identifying the focus of epileptic seizures in patients who appear to have nonlesional epilepsy on standard imaging techniques, researchers report in Science Translational Medicine.

16 Oct 2015

New method uses advanced noninvasive neuroimaging to localize and identify epileptic lesions

Epilepsy affects more than 65 million people worldwide. One-third of these patients have seizures that are not controlled by medications. In addition, one-third have brain lesions, the hallmark of the disease, which cannot be located by conventional imaging methods.

15 Oct 2015

UW researchers use noninvasive light-based imaging technology to see inside the living brain

Researchers at the University of Washington have used a noninvasive light-based imaging technology to literally see inside the living brain, providing a new tool to study how diseases like dementia, Alzheimer's, and brain tumors change brain tissue over time.

13 Oct 2015

New book highlights sophisticated neurogenic processes in adult mammalian brain

In discrete locations of the adult brain, new neurons are born from stem cells that differentiate, migrate, and integrate into the existing neural network. This process is implicated in normal brain functions such as memory formation and is disrupted in many disease states, including Alzheimer's, schizophrenia, and depression.

7 Oct 2015

Multicenter study shows Monteris’ NeuroBlate System improves outcome in brain tumor patients

Monteris Medical today announced recent data demonstrating that newly diagnosed brain tumor patients undergoing procedures with the NeuroBlate System, a minimally invasive robotic laser thermotherapy tool, experienced improved outcomes.

1 Oct 2015

Brain prosthesis may help individuals suffering from memory loss

Researchers at USC and Wake Forest Baptist Medical Center have developed a brain prosthesis that is designed to help individuals suffering from memory loss.

30 Sep 2015

Glowing protein may replace fiber optic cable as light source in optogenetics research

Optogenetics has taken neuroscience by storm in recent years because the technique allows scientists to study the brain conveniently in animals, activating or inhibiting selected groups of neurons at the flip of a switch. Most often, scientists use a fiber optic cable to deliver light into the brain.

30 Sep 2015

Ocean cells contribute to contextual learning process, shows research

When we misplace something, retracing our steps often helps us remember where we put it because environmental contexts are strongly linked to memory formation.

26 Sep 2015

New study heightens concerns over detrimental impact of air pollution on gene associated with AD risk

A new study by researchers at the Universities of Montana, Valle de México, Boise State, and North Carolina, the Centro de Ciencias de la Atmósfera, Universidad Nacional Autónoma de México, Instituto Nacional de Pediatría, and Centro Médico Cozumel heightens concerns over the detrimental impact of air pollution on hippocampal metabolites as early markers of neurodegeneration in young urbanites carrying an allele 4 of the apolipoprotein E gene (APOE).

26 Sep 2015

MIT neuroscientists identify brain circuit critical in forming episodic memory

When you remember a particular experience, that memory has three critical elements -- what, when, and where. MIT neuroscientists have now identified a brain circuit that processes the "when" and "where" components of memory.

24 Sep 2015

Findings may suggest new therapeutic target to combat memory loss in aging, Alzheimer's disease

Northwestern Medicine scientists have examined activity in a little-studied part of the brain associated with memory and found for the first time the reason that neurons there become more active in old age, findings that may suggest a new target for future therapies to combat memory loss in aging and Alzheimer's disease.

23 Sep 2015

A three-step brain oscillation plays significant role in memory consolidation

Our long-term memory is consolidated when we sleep. Short-term memory traces in the hippocampus, an area deep in the brain, are then relocated to more outer parts of the brain. An international team of neuroscientists, among who Mathilde Bonnefond and Til Ole Bergmann from the Donders Institute at Radboud Universiy, now shows how a three-step brain oscillation plays an important part in that process.

22 Sep 2015

Salsalate drug offers new hope for treating Alzheimer's disease and FTD

Scientists from the Gladstone Institutes have discovered that salsalate, a drug used to treat rheumatoid arthritis, effectively reversed tau-related dysfunction in an animal model of frontotemporal dementia (FTD). Salsalate prevented the accumulation of tau in the brain and protected against cognitive impairments resembling impairments seen in Alzheimer's disease and FTD.

21 Sep 2015

AgeneBio's HOPE4MCI Phase 3 trial receives support from NIH

AgeneBio, a biopharmaceutical company developing innovative therapeutics for unserved patients battling neurodegeneration, announced today that its HOPE4MCI Phase 3 clinical trial has received support from the National Institutes of Health.

15 Sep 2015

University of Basel scientists identify genes that play central role in development of Alzheimer's disease

Genes are not only important for regular memory performance, but also for the development of Alzheimer's disease. Researchers at the University of Basel now identified a specific group of genes that plays a central role in both processes. This group of molecules controls the concentration of calcium ions inside the cell.

3 Sep 2015

Hippocampus in the brain's temporal lobe involved in quick, successful conflict resolution

The hippocampus in the brain's temporal lobe is responsible for more than just long-term memory. Researchers have for the first time demonstrated that it is also involved in quick and successful conflict resolution.

21 Aug 2015

Stress hormone cortisol tied to thinking problems in healthy older people

Testing the saliva of healthy older people for the level of the stress hormone cortisol may help identify individuals who should be screened for problems with thinking skills, according to a study published in the August 19, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

20 Aug 2015

Scientists reveal link between smaller hippocampal brain volume and marijuana use

How scientists study the effects of marijuana on the brain is changing. Until recently marijuana research largely excluded tobacco users from its participant pool, but scientists at the Center for BrainHealth at The University of Texas at Dallas have found reason to abandon this practice, uncovering significant differences in the brains of individuals who use both tobacco and marijuana and the brains of those who only use marijuana.

19 Aug 2015

Scientists discover special brain mechanism that can retrieve unconscious memories

Some stressful experiences - such as chronic childhood abuse - are so overwhelming and traumatic, the memories hide like a shadow in the brain.

18 Aug 2015

Scientists identify where the brain records time and place of real-life memories

For the first time, scientists have seen evidence of where the brain records the time and place of real-life memories. Results showed that the similarity of the brain activation patterns when memories were recalled was an indicator of the breadth of space and time between the actual events.