Hyperglycemia News and Research

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Hyperglycemia occurs when you have a higher than usual level of glucose in your blood. This can happen shortly after you have eaten a big meal and is not a problem if your glucose level returns to normal. Cells remove glucose from the blood in response toinsulin. If your pancreas doesn't make enough insulin, glucose can't enter the cells and remains in the blood. Blood glucose levels can also get too high if cells areunable to respond to insulin properly (insulinresistance). Without glucose, your cells are unable to make energy and can't function properly.

Type 2 diabetes cytokine elevation places teeth at risk

Scientists have detected significant differences in the cytokine and chemokine make up of gingival crevicular fluid taken from chronic periodontitis patients with uncontrolled Type 2 diabetes and those without.

21 Nov 2013

Skeletal problems now added to list of diabetes complications

The list of complications from type 2 diabetes is long: vascular and heart disease, eye problems, nerve damage, kidney disease, hearing problems and Alzheimer's disease. Physicians have long thought of osteoporosis as another outcome. Based on a Mayo Clinic study published in the Journal of Bone and Mineral Research, that's confirmed: You can definitely add skeletal problems to that list.

14 Nov 2013

Normal blood sugar regulation depends on partnership between pancreas and brain

A growing body of evidence suggests that the brain plays a key role in glucose regulation and the development of type 2 diabetes, researchers write in the Nov. 7 issue of the journal Nature.

6 Nov 2013

"Good" cholesterol improves blood glucose levels, say scientists

High density lipoprotein cholesterol (HDL), the so-called "good" cholesterol improves blood glucose levels by enhancing skeletal muscle function and reducing adiposity, scientists of the Helmholtz Zentrum München report in the current issue of the renown American Heart Association Journal ‚Circulation'.

31 Oct 2013

Brain-derived neurotrophic factor may inhibit glucose intolerance after cerebral ischemia

Interestingly, a recent study found that ischemic stress causes hyperglycemia and may worsen ischemic neuronal damage. In addition, decreased insulin sensitivity after ischemic stress seems to be involved in the development of post-ischemic glucose intolerance.

30 Oct 2013

Once-daily prescription medicine for COPD now available throughout the U.S.

GlaxoSmithKline plc and Theravance, Inc. today announced that BREO ELLIPTA, a once-daily prescription medicine for chronic obstructive pulmonary disease, is now available to pharmacies throughout the U.S.

30 Oct 2013

Study: Glucose levels, vascular damage contribute to dementia

High blood-sugar levels, such as those linked with Type 2 diabetes, make beta amyloid protein associated with Alzheimer's disease dramatically more toxic to cells lining blood vessels in the brain, according to a new Tulane University study published in latest issue of the Journal of Alzheimer's Disease.

29 Oct 2013

Testosterone treatment in hypogonadal men may reduce cardiovascular disease risk

Research from Boston University School of Medicine suggests that testosterone treatment in hypogonadal (testosterone deficient) men restores normal lipid profiles and may reduce the risk of cardiovascular disease. These finding currently appear online in the International Journal of Clinical Practice.

24 Oct 2013

Levemir FlexTouch insulin pen receives approval from Health Canada for treatment of diabetes

Novo Nordisk today announced that Health Canada has approved Levemir® FlexTouch®, a disposable prefilled insulin pen containing Levemir® (insulin detemir). Levemir® FlexTouch® has been designed to improve ease of use for insulin administration and to help decrease barriers to good treatment adherence for Canadians living with type 1 and type 2 diabetes mellitus (diabetes).

19 Oct 2013

UCLA, Takeda to study how disruption of circadian rhythms promotes type 2 diabetes

Millions of individuals worldwide are exposed to shift work and numerous environmental conditions that disturb circadian clock function and disrupt normal circadian rhythms. Environmental conditions associated with disrupted circadian rhythms greatly increase the risk for development of type 2 diabetes and metabolic syndrome and also hinder the treatment and management of hyperglycemia in existing patients with diabetes.

13 Oct 2013

Hyperglycemia heightens pneumonia risk in pediatric burns patients

Research indicates that hyperglycemia puts pediatric burns patients at increased risk for pneumonia.

8 Oct 2013

High blood glucose levels associated with higher risk of wound-related complications

A new study released today shows that among patients undergoing surgery for chronic wounds related to diabetes, the risk of wound-related complications is affected by how well the patient's blood sugar levels are controlled before surgery. These findings appear in the October issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

2 Oct 2013

Discovery paves way for new therapeutic strategies to protect heart health of diabetes patients

UC Davis Health System researchers have identified for the first time a biological pathway that is activated when blood sugar levels are abnormally high and causes irregular heartbeats, a condition known as cardiac arrhythmia that is linked with heart failure and sudden cardiac death.

1 Oct 2013

Glucose monitoring systems detect RBC and other interferents in burn patients blood

Glucose monitoring systems with an autocorrect feature that can detect red blood cells (hematocrit), vitamin C and other common interferents in burn patients' blood are better for monitoring care, a pilot study conducted by UC Davis researchers at the School of Medicine and College of Engineering has found.

30 Aug 2013

Study points to potential new therapeutic target for preventing birth defects in women with diabetes

A research team at the University of Maryland School of Medicine has identified a cell signaling pathway which plays a significant role in causing developmental defects of the fetal spinal cord and brain in babies of women with diabetes.

29 Aug 2013

Diabetic patients taking oral fluoroquinolones may have high risk of severe blood sugar-related problems

Diabetic patients taking oral fluoroquinolones, a frequently prescribed class of antibiotics, were found to have a higher risk of severe blood sugar-related problems than diabetic patients taking other kinds of antibiotics, according to a recent study from Taiwan published in Clinical Infectious Diseases.

16 Aug 2013

Regeneron, Bayer report positive results from Phase 3 VIVID-DME and VISTA-DME trials of EYLEA for DME

Regeneron Pharmaceuticals, Inc. and Bayer HealthCare today announced that in the Phase 3 VIVID-DME and VISTA-DME trials of EYLEA (aflibercept) Injection for the treatment of diabetic macular edema, EYLEA 2 milligrams (mg) dosed monthly and EYLEA 2 mg dosed every two months (after 5 initial monthly injections) achieved the primary endpoint of a significantly greater improvement in best-corrected visual acuity from baseline compared to laser photocoagulation at 52 weeks.

6 Aug 2013

FDA recalls Nova Max Blood Glucose Test Strips due to faulty readings

The U.S. Food and Drug Administration is working with Nova Diabetes Care to recall 21 lots of glucose test strips marketed under the brand names Nova Max Blood Glucose Test Strips and Nova Max Plus Glucose Meter Kits. Nova Diabetes Care announced a recall on July 26, 2013.

1 Aug 2013

Genetics could help women at risk of developing gestational diabetes

New Northwestern Medicine- research on the genetics of diabetes could one day help women know their risk for developing gestational diabetes before they become pregnant -- and lead to preventive measures to protect the health of offspring.