Immunotherapy News and Research RSS Feed - Immunotherapy News and Research

Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.
Northwestern Medicine investigators to lead clinical trial for people with rare cancers

Northwestern Medicine investigators to lead clinical trial for people with rare cancers

A novel national trial for people with no established alternative to treat their rare cancers is being co-led by Northwestern Medicine investigators, who helped conceive of and develop the project. [More]
ICLIO white paper spotlights top-level concerns in delivering immunotherapies for cancer

ICLIO white paper spotlights top-level concerns in delivering immunotherapies for cancer

While momentum around immunotherapies for cancer continues to build, the high cost of these therapies places them at the center of debate about how best to define and measure value in cancer care. [More]
Inactive B2M genes can condition response of lung cancer patients to immunotherapy, study shows

Inactive B2M genes can condition response of lung cancer patients to immunotherapy, study shows

Researchers from the Genes and Cancer research group at the Bellvitge Biomedical Research Institute have identified inactivating mutations in a number of genes that code for HLA-I histocompatibility complex proteins, which are involved in the immune response and can condition the tesponse of lung cancer patients to immunotherapy. [More]
Research offers new clues to prolong lifespan of the body's disease-fighting NK cells

Research offers new clues to prolong lifespan of the body's disease-fighting NK cells

A team of researchers from Australia and France have uncovered new insights into how to prolong the lifespan of the body's disease-fighting natural killer (NK) cells. [More]
Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

Each day, more than 1,600 people die from cancer in the US, and 450 in the UK, mostly because the disease has spread beyond a stage when surgery is an effective cure and has become resistant to therapy. Despite decades of research, understanding why cancer cells become invasive has remained shrouded in mystery. [More]
New antibody design may pave way for treating diseases affecting the brain

New antibody design may pave way for treating diseases affecting the brain

Immunotherapy has proven to be effective against many serious diseases. But to treat diseases in the brain, the antibodies must first get past the obstacle of the blood-brain barrier. [More]
MUSC scientists design novel antibody-based therapy to fight against cancer

MUSC scientists design novel antibody-based therapy to fight against cancer

Scientists at the Medical University of South Carolina (MUSC) have designed an antibody-based therapy that could target the functions of TGF-beta that cause cancer [More]
Cancers acquire resistance to immunotherapy by eliminating tumor-specific genetic mutations

Cancers acquire resistance to immunotherapy by eliminating tumor-specific genetic mutations

Results of an initial study of tumors from patients with lung cancer or head and neck cancer suggest that the widespread acquired resistance to immunotherapy drugs known as checkpoint inhibitors may be due to the elimination of certain genetic mutations needed to enable the immune system to recognize and attack malignant cells. [More]
New research suggests novel combination approach to fight against gliomas

New research suggests novel combination approach to fight against gliomas

"Devastating" and "dismal." That's how leading researchers describe the present outlook for malignant brain tumors. The median survival rate for patients with glioblastoma multiforme, or GBM, is a mere 14.2 months. [More]
Study suggests new options for improving cancer immunotherapy

Study suggests new options for improving cancer immunotherapy

One of the main reasons cancer remains difficult to treat is that cancer cells have developed a multitude of mechanisms that allow them to evade destruction by the immune system. [More]
Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutch’s new Evergreen Fund to promote commercialization of research into lifesaving therapies

Fred Hutchinson Cancer Research Center announced its first-ever grants from its newly established Evergreen Fund to spur researchers' efforts to advance bold ideas toward creating or partnering with a commercial entity. [More]
Nanodiscs deliver customized therapeutic vaccine for treatment of colon, melanoma cancers

Nanodiscs deliver customized therapeutic vaccine for treatment of colon, melanoma cancers

Researchers at the University of Michigan have had initial success in mice using nanodiscs to deliver a customized therapeutic vaccine for the treatment of colon and melanoma cancer tumors. [More]
Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

In experiments on mice with a form of aggressive brain cancer, Johns Hopkins researchers have shown that localized chemotherapy delivered directly to the brain rather than given systemically may be the best way to keep the immune system intact and strong when immunotherapy is also part of the treatment. [More]
Dual treatment strategies lengthen lives of mice with skin cancer

Dual treatment strategies lengthen lives of mice with skin cancer

By combining two treatment strategies, both aimed at boosting the immune system's killer T cells, Johns Hopkins researchers report they lengthened the lives of mice with skin cancer more than by using either strategy on its own. [More]
Sanford study explores protein's role in improving survival of ovarian cancer patients

Sanford study explores protein's role in improving survival of ovarian cancer patients

A Sanford Research lab is studying a protein's role in improving survival in ovarian cancer patients. Findings published in Oncogenesis indicate a higher level of a specific protein correlates with an increased survival rate and decrease in the spreading of cancer cells. [More]
Study addresses cost-effectiveness of checkpoint inhibitors for advanced melanoma in Hong Kong

Study addresses cost-effectiveness of checkpoint inhibitors for advanced melanoma in Hong Kong

Immunotherapy with pembrolizumab has been deemed a cost-effective first line treatment for advanced melanoma patients in Hong Kong, researchers report at the ESMO Asia 2016 Congress in Singapore. [More]
Routine blood test can predict survival of cancer patients in palliative care

Routine blood test can predict survival of cancer patients in palliative care

A routine blood test can predict how long cancer patients in palliative care will survive, researchers report at the ESMO Asia 2016 Congress in Singapore. [More]
Researchers develop new method to identify antigens for cancer treatment

Researchers develop new method to identify antigens for cancer treatment

New cancer therapies harness the immune system to fight tumors. One of the main principles behind these therapies is to find out precisely which molecules on cancer cells trigger an immune response. [More]
Researchers identify attractive drug candidate to target glioma tumors

Researchers identify attractive drug candidate to target glioma tumors

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed. [More]
Common bacterium that causes gum infections may trigger rheumatoid arthritis

Common bacterium that causes gum infections may trigger rheumatoid arthritis

Investigators at Johns Hopkins report they have new evidence that a bacterium known to cause chronic inflammatory gum infections also triggers the inflammatory "autoimmune" response characteristic of chronic, joint-destroying rheumatoid arthritis (RA). [More]
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