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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.
Type 1 diabetes patients show distinct signs of gut inflammation, study reveals

Type 1 diabetes patients show distinct signs of gut inflammation, study reveals

People with Type 1 diabetes exhibit inflammation in the digestive tract and gut bacteria¬—a pattern that differs from individuals who do not have diabetes or those who have celiac disease, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
TSRI scientists develop new method to enhance drug discovery and protein research

TSRI scientists develop new method to enhance drug discovery and protein research

A team led by scientists at The Scripps Research Institute (TSRI) has developed a versatile new method that should enhance the discovery of new drugs and the study of proteins. [More]
Exposure to insecticides that mimic melatonin could put people at higher risk for diabetes

Exposure to insecticides that mimic melatonin could put people at higher risk for diabetes

Synthetic chemicals commonly found in insecticides and garden products bind to the receptors that govern our biological clocks, University at Buffalo researchers have found. [More]
Scientists developing painless ‘smart’ patch that releases insulin in response to rising glucose levels

Scientists developing painless ‘smart’ patch that releases insulin in response to rising glucose levels

Treatment for certain diabetes cases involves constant monitoring of blood-glucose levels and daily insulin shots. [More]
Calorie restriction helps rhesus monkeys lead longer and healthier lives, report shows

Calorie restriction helps rhesus monkeys lead longer and healthier lives, report shows

Settling a persistent scientific controversy, a long-awaited report shows that restricting calories does indeed help rhesus monkeys live longer, healthier lives. [More]
People with metabolic syndrome may need more vitamin E, new research shows

People with metabolic syndrome may need more vitamin E, new research shows

New research has shown that people with metabolic syndrome need significantly more vitamin E - which could be a serious public health concern, in light of the millions of people who have this condition that's often related to obesity. [More]
Every meal triggers short-term inflammatory responses in healthy individuals

Every meal triggers short-term inflammatory responses in healthy individuals

When we eat, we do not just take in nutrients - we also consume a significant quantity of bacteria. The body is faced with the challenge of simultaneously distributing the ingested glucose and fighting these bacteria. [More]
People with schizophrenia more likely to have diabetes than general population

People with schizophrenia more likely to have diabetes than general population

People with early schizophrenia are at an increased risk of developing diabetes, even when the effects of antipsychotic drugs, diet and exercise are taken out of the equation, according to an analysis by researchers from King's College London. [More]
Could pathogen infection really lead to Alzheimer’s?

Could pathogen infection really lead to Alzheimer’s?

New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which... [More]
Resistance-based interval training can improve blood vessel function, study shows

Resistance-based interval training can improve blood vessel function, study shows

Just one session of interval weight-training can improve the risk of Type 2 diabetes complications, according to a UBC Okanagan study. This is encouraging news for those starting the New Year with good intentions. [More]
Childhood obesity starts in the womb?

Childhood obesity starts in the womb?

There is incontrovertible evidence that some harmful drugs and toxins can affect lifelong health. For example, if women take certain drugs in pregnancy, such as thalidomide, there are well documented effects on lifelong health. These have obvious and dramatic effects on the child... [More]
SLU expert suggests viewing exercise as daily contribution that offers cumulative health benefits

SLU expert suggests viewing exercise as daily contribution that offers cumulative health benefits

Have you already faltered on your New Year's resolution to exercise regularly in 2017? Joined a gym, but only worked out two days so far? New workout gear still neatly folded with tags attached? Don't give up your admirable ambition just yet. Instead, consider a new attitude to refocus your approach toward your exercise goal. [More]
Study examines role of risk factors in development of ER-positive and ER-negative breast cancers

Study examines role of risk factors in development of ER-positive and ER-negative breast cancers

Karla Kerlikowske, MD, and team recently published a paper in the Journal of the National Cancer Institute that examined the role of common risk factors in the development of ER-positive and ER-negative breast cancers. [More]
Epigenetic changes favor development of fatty liver in humans and mice

Epigenetic changes favor development of fatty liver in humans and mice

Mice with a strong tendency to obesity already exhibit epigenetic changes at six weeks of age, inducing the liver to amplify its production of the enzyme DPP4 and release it into the circulation. Over the long term, this favors the development of a fatty liver. [More]
Researchers discover natural regeneration process for scar-free skin repair

Researchers discover natural regeneration process for scar-free skin repair

Scars are often the unwanted and permanent result of wound healing, but University of California, Irvine and University of Pennsylvania researchers have discovered a natural regeneration process that stimulates scar-free skin repair. [More]
Why WAIT program offers new hope to obese patients with diabetes

Why WAIT program offers new hope to obese patients with diabetes

Joslin Diabetes Center's intensive life-style intervention program for obese patients with diabetes continues to offer health benefits for participants five years after they begin the intervention, a new study demonstrates. [More]
Researchers uncover reason for stent failure in diabetic patients with clogged arteries

Researchers uncover reason for stent failure in diabetic patients with clogged arteries

People with any form of diabetes are at greater risk of developing cardiovascular conditions than people without the disease. Moreover, if they undergo an operation to open up a clogged artery by inserting a "stent" surgical tube, the artery is much more likely to clog up again. [More]
How does the brain control appetite?

How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body. [More]
Chemical modification improves release and availability of insulin, research shows

Chemical modification improves release and availability of insulin, research shows

Replacing a hydrogen atom by an iodine atom in insulin, the hormone retains its efficacy but is available more rapidly to the organism. [More]
AMPK enzyme plays vital role in enhancing muscle insulin sensitivity after physical activity

AMPK enzyme plays vital role in enhancing muscle insulin sensitivity after physical activity

ampk Physical activity benefits diabetics and others with insulin resistance. One of the reasons is that a single bout of physical activity increases the effectiveness of insulin. [More]
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