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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.
Appetite hormone CART helps increase insulin secretion, reduce glucagon production

Appetite hormone CART helps increase insulin secretion, reduce glucagon production

The study shows that the appetite hormone CART not only controls the sensation of satiety, but it also helps increase insulin secretion and decrease glucagon production. [More]
Excess or insufficient sleep may increase diabetes risk in men

Excess or insufficient sleep may increase diabetes risk in men

Men who sleep either fewer or more hours than average may face a greater risk of developing diabetes, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
Experimental lipid-lowering drug improves glucose control in diabetic patients

Experimental lipid-lowering drug improves glucose control in diabetic patients

High triglycerides -- a type of fat, or lipid, in the blood -- increase the risk of heart disease and perhaps type 2 diabetes. For the first time, it has been shown that profoundly lowering triglycerides in diabetics improves their insulin sensitivity over time, which helps them maintain healthy glucose - blood sugar -- levels. [More]
Pioglitazone effective in diabetes patients with NASH

Pioglitazone effective in diabetes patients with NASH

Pioglitazone may halt the progression of nonalcoholic steatohepatitis in patients with prediabetes or Type 2 diabetes, a randomised trial shows. [More]
Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Why does appetite loss occur during illness? An interview with Prof. Conti and Prof. Francesconi

Appetite, as a word, come from the Latin appetitus, meaning "desire for.” Therefore, appetite can be defined as a pleasurable sensation or the desire to eat. This sensation is coordinated by several brain areas associated with reward processing such amygdala, hippocampus, ventral pallidum, nucleus accumbens and striatum, and others. [More]
The scent dogs smell on diabetics’ breath could offer key to new tests

The scent dogs smell on diabetics’ breath could offer key to new tests

An increase in the level of the chemical isoprene may be the warning sign some dogs can detect in the breath of patients with type 1 diabetes who are reaching risky low levels of blood sugar, according to research by the University of Cambridge. [More]
Blood mannose levels could help predict type 2 diabetes risk

Blood mannose levels could help predict type 2 diabetes risk

Even if you are not overweight, your mannose levels may indicate whether you're at risk for type 2 diabetes (T2D) or insulin resistance (IR), a Swedish study shows. [More]
Mice study shows influence of dad's obesity on daughter’s body weight and breast cancer risk

Mice study shows influence of dad's obesity on daughter’s body weight and breast cancer risk

Obese male mice and normal weight female mice produce female pups that are overweight at birth through childhood, and have delayed development of their breast tissue as well as increased rates of breast cancer. [More]
Latest online version of German Diabetes Risk Score optimized for mobile devices

Latest online version of German Diabetes Risk Score optimized for mobile devices

The German Institute of Human Nutrition has updated the online version of its German Diabetes Risk Score and has optimized it for mobile devices. [More]
Highly structured nutrition therapy provides substantial impact on A1C, body weight and lipid profiles

Highly structured nutrition therapy provides substantial impact on A1C, body weight and lipid profiles

Researchers at Joslin Diabetes Center have announced the results of a study that may change how nutrition therapy is delivered to overweight and obese patients with type 2 diabetes. [More]
SORLA protein makes fat cells oversensitive to insulin

SORLA protein makes fat cells oversensitive to insulin

SORLA is a protein that influences the balance of metabolic processes in adipose tissue, a particular form of fat. Too much of it makes fat cells overly sensitive to insulin, which leads them to break down less fat. SORLA was previously known for its protective role in Alzheimer's disease. [More]
Clinical trial finds pioglitazone drug safe and effective for NASH patients

Clinical trial finds pioglitazone drug safe and effective for NASH patients

Researchers have found that an existing diabetes drug can be used to halt progression of another disease that is a leading cause of liver transplants. [More]
Scientists aim to explore how gestational diabetes can put babies at lifelong risk for cardiovascular disease

Scientists aim to explore how gestational diabetes can put babies at lifelong risk for cardiovascular disease

Gestational diabetes can put babies at a lifelong risk for cardiovascular disease, and scientists want to better understand how. [More]
Mother's obesity can impair health of future generations

Mother's obesity can impair health of future generations

New research suggests that mothers who eat high-fat, high-sugar diets can predispose multiple generations to metabolic problems, even if their offspring consume healthy diets. [More]
Mice study highlights vital role of liver in balancing fats and sugars

Mice study highlights vital role of liver in balancing fats and sugars

Sugar in the form of blood glucose provides essential energy for cells. When its usual dietary source — carbohydrates — is scarce, the liver can produce it with the aid of fat. [More]
Study sheds new light on how overeating may lead to more eating

Study sheds new light on how overeating may lead to more eating

Research is finally beginning to shed light on some of the reasons that extra weight is difficult to shed permanently. Now, a new study has uncovered another method by which the gut senses how much food a person eats and relays that to the brain. [More]
IGF-1 protein may be key to prevent heart disease in older adults

IGF-1 protein may be key to prevent heart disease in older adults

As men and women grow older, their chances for coronary heart disease also increase. Atherosclerosis is a condition in which plaque builds up inside the arteries, which can lead to serious problems, including heart attacks, strokes or even death. [More]
Diet modification could help improve quality of life in women with ovarian cancer

Diet modification could help improve quality of life in women with ovarian cancer

New research conducted at the University of Alabama at Birmingham has shown that a particular type of diet could help women with ovarian cancer to lose weight and improve their quality of life and cancer-related measures. [More]
Brain's reward system in obese people operates differently in response to food and dopamine

Brain's reward system in obese people operates differently in response to food and dopamine

As young people reach adulthood, their preferences for sweet foods typically decline. But for people with obesity, new research suggests that the drop-off may not be as steep and that the brain's reward system operates differently in obese people than in thinner people, which may play a role in this phenomenon. [More]
Nut consumption may lower risk of overall mortality in prostate cancer patients

Nut consumption may lower risk of overall mortality in prostate cancer patients

In a large prospective study published online in the British Journal of Cancer, researchers looked at the association between nut consumption and prostate cancer risk and mortality among 47,299 men in the Health Professionals Follow-up Study. [More]
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