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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.
Researchers develop new drugs for melanoma

Researchers develop new drugs for melanoma

Finding new, more effective and personalised treatments for cancer is the challenge of many researchers. A challenge that has been successfully met by a team from Inserm led by Stéphane Rocchi, which has just synthesised and developed new drugs for melanoma. [More]
NR supplements can reduce diabetes-related complications in mice

NR supplements can reduce diabetes-related complications in mice

A naturally occurring vitamin, nicotinamide riboside (NR), can lower blood sugar levels, reduce fatty liver, and prevent peripheral nerve damage in mouse models of prediabetes and type 2 diabetes (T2D), according to a new study by researchers at the University of Iowa and the Iowa City VA Health Care System. [More]
Smell or taste of food can shorten lifespan by affecting sensory neurons

Smell or taste of food can shorten lifespan by affecting sensory neurons

Animals can perceive changes in many environmental factors such as temperature and the taste or smell of foods. This is achieved by specialized nerve cells called sensory neurons. Interestingly, sensory neurons have been known to control the rate of aging in various animals, including the tiny free living roundworm C. elegans. [More]
Majority of young adults with abdominal obesity unaware of CKD risk

Majority of young adults with abdominal obesity unaware of CKD risk

Many young adults with abdominal obesity exhibit a readily detectable risk factor for chronic kidney disease (CKD), yet the vast majority don't know they're at risk, according to a study of nationwide health data led by Albert Einstein College of Medicine researchers that was published online today in the journal PLOS ONE. [More]
WPI receives patent for novel method of reprogramming human skin cells

WPI receives patent for novel method of reprogramming human skin cells

Cell therapies for a range of serious conditions, including heart attacks, diabetes, and traumatic injuries, will be accelerated by research at Worcester Polytechnic Institute that yielded a newly patented method of converting human skin cells into engines of wound healing and tissue regeneration. [More]
Study finds gap in screening for lipid abnormalities among adults taking antipsychotic medications

Study finds gap in screening for lipid abnormalities among adults taking antipsychotic medications

Too few adults taking antipsychotic medications are being screened for abnormalities in lipids, which include cholesterol and triglycerides, new research from the University of Colorado Anschutz Medical Campus finds. [More]
Study links low- and high-birthweight babies to increased cardiovascular disease risk

Study links low- and high-birthweight babies to increased cardiovascular disease risk

For reasons that remain unclear at least in the smaller babies, both birthweight extremes appear to increase the likelihood of early development of dangerous fat around major organs in the abdomen that significantly increases these risks, said Dr. Brian Stansfield, neonatologist at the Children's Hospital of Georgia and the Medical College of Georgia at Augusta University. [More]
Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

Epigenetic modification of Igfbp2 gene may increase risk of obesity and fatty liver

Scientists of the German Center for Diabetes Research led by the German Institute of Human Nutrition have shown in a mouse model that the epigenetic modification of the Igfbp2 gene observed in the young animal precedes a fatty liver in the adult animal later in life. [More]
Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Four major phenotypes may help improve prediction, prevention of cardiometabolic risk in prediabetes

Prediabetes is associated with increased risk of diabetes, cardiovascular disease, dementia and cancer. However, the disease risk considerably varies among subjects. [More]
Cardioprotective effect proposed for metformin

Cardioprotective effect proposed for metformin

A large retrospective analysis suggests that metformin could be cardioprotective in insulin-dependent patients with Type 2 diabetes. [More]
Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

Researchers identify single RCAN1 gene responsible for onset of type 2 diabetes

RESEARCHERS have identified the gene they believe is responsible for the onset of type 2 diabetes, sparking hope for treatments to prevent and possibly reverse the progressive condition. [More]
PYY hormone may offer effective treatment for type 2 diabetes

PYY hormone may offer effective treatment for type 2 diabetes

Researchers at the Norwegian University of Science and Technology and Oxford University have found a hormone that may offer an effective treatment for type 2 diabetes. [More]
TAK1 deficit protects mice from obesity

TAK1 deficit protects mice from obesity

Obesity and subsequent complications are increasing in frequency worldwide. The accumulation of adipose tissue is associated with increased inflammation, and it has been proposed that modification of proinflammatory responses could alter adipose tissue composition. [More]
Exposure to bright light may influence metabolism

Exposure to bright light may influence metabolism

Exposure to bright light could affect your metabolism, reports a new Northwestern Medicine study. [More]
CGT, University of Aberdeen announce creation of new company to develop novel technology for diabetes treatment

CGT, University of Aberdeen announce creation of new company to develop novel technology for diabetes treatment

The Cell and Gene Therapy Catapult and University of Aberdeen, UK, today announce the creation of Islexa, a new company developing a novel technology to produce laboratory grown islets, the organoids responsible for insulin production. [More]
Insulin pump therapy can benefit all type 1 diabetes patients

Insulin pump therapy can benefit all type 1 diabetes patients

Insulin pump therapy contributes to better blood glucose control in type 1 diabetes and, as pump technology continues to improve and become part of sensor-controlled feedback and artificial pancreas systems, essentially all patients would benefit from their capabilities according to a Commentary published in Diabetes Technology & Therapeutics (DTT), a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. [More]
McGill researchers discover role of folliculin protein in regulating activity of fat cells

McGill researchers discover role of folliculin protein in regulating activity of fat cells

Researchers have uncovered a new molecular pathway for stimulating the body to burn fat - a discovery that could help fight obesity, diabetes and cardiovascular disease. [More]
Sleep hormone melatonin may be responsible for type 2 diabetes risk among overnight workers

Sleep hormone melatonin may be responsible for type 2 diabetes risk among overnight workers

A new experimental and clinical study from Lund University in Sweden shows that the sleep hormone melatonin impairs insulin secretion in people with a common gene variant. [More]
Chronic alcohol exposure could negatively impact pancreas' ability to absorb vitamin C

Chronic alcohol exposure could negatively impact pancreas' ability to absorb vitamin C

Chronic exposure to alcohol interferes with the pancreas' ability to absorb vitamin C, potentially predisposing the body to pancreatitis and other pancreatic diseases, a new study in the American Journal of Physiology—Cell Physiology reports. [More]
Combination of two compounds found in red grapes, oranges could treat diseases

Combination of two compounds found in red grapes, oranges could treat diseases

A combination of two compounds found in red grapes and oranges could be used to improve the health of people with diabetes, and reduce cases of obesity and heart disease. [More]
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