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Thioridazine works by weakening staphylococcal cell wall, new study reveals

In 2008 researchers from the University of Southern Denmark showed that the drug thioridazine, which has previously been used to treat schizophrenia, is also a powerful weapon against antibiotic-resistant bacteria such as staphylococci (Staphylococcus aureus).

18 May 2013

New LAMP malaria test to improve diagnosis for imported UK cases

A new, highly sensitive blood test that quickly detects even the lowest levels of malaria parasites in the body could make a dramatic difference in efforts to tackle the disease in the UK and across the world, according to new research published in the Journal of Infectious Diseases.

17 May 2013

Columbia University signs licensing agreement with Varian Medical Systems for novel imaging software

Columbia University has signed a licensing agreement with Varian Medical Systems for novel imaging software that facilitates 3-D segmentation, the process by which anatomical structures in medical images are distinguished from one another-an important step in the precise planning of cancer surgery and radiation treatments.

17 May 2013

Weekend reading: Volunteers in the battle with heart disease; Psychiatry without medication; Owning your genes

Psychiatrists who take time with their patients are not the norm. It's not because others don't care. Rather the system rewards efficiency, not empathy.

17 May 2013

Viewpoints: When a doctor should keep quiet; 2 views of hospital pricing; Stem cell 'snake oil'

In medical school, we were taught not to withhold information from our patients or to be "paternal" in making decisions for them. We internalized the idea that fully informed patients are better equipped to make treatment decisions.

17 May 2013

New research reveals how endothelium maintains highly efficient barrier function

The endothelium, the cellular layer lining the body's blood vessels, is extremely resilient. Measuring just a few hundred nanometers in thickness, this super-tenuous structure routinely withstands blood flow, hydrostatic pressure, stretch and tissue compression to create a unique and highly dynamic barrier that maintains the organization necessary to partition tissues from the body's circulatory system.

17 May 2013

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells, in the laboratory. The researchers showed that, in mice, the tissue can be used to foster the development of white blood cells the body needs to mount healthy immune responses and to prevent harmful autoimmune reactions.

17 May 2013

Research shows new neural circuits arise when hippocampus is disabled

When the brain's primary "learning center" is damaged, complex new neural circuits arise to compensate for the lost function, say life scientists from UCLA and Australia who have pinpointed the regions of the brain involved in creating those alternate pathways - often far from the damaged site.

17 May 2013

UT Arlington physicist develops new tool to map, track interactions between neurons inside the brain

A new tool being developed by UT Arlington assistant professor of physics could help scientists map and track the interactions between neurons inside different areas of the brain.

17 May 2013

RIKEN researchers visualize memory formation for first time in zebrafish

In our interaction with our environment we constantly refer to past experiences stored as memories to guide behavioral decisions. But how memories are formed, stored and then retrieved to assist decision-making remains a mystery.

17 May 2013

Novel cell sorting enhancement to MoFlo Astrios platform to be introduced by Beckman Coulter Life Sciences at CYTO 2013

Two seminars and seven poster sessions, Beckman Coulter will have a prominent role when CYTO 2013 convenes at the San Diego Convention Center May 18-22, 2013.

From Beckman Coulter Life Sciences - Flow Cytometry 16 May 2013

Transgenomic launches new mutation detection test for patients with metastatic colorectal cancer

Transgenomic, Inc. today announced the global, commercial availability of CRC RAScan, a new mutation detection test to screen patients with metastatic colorectal cancer for RAS mutations (KRAS and NRAS).

16 May 2013

Scientists reveal inside story of European regulatory review and approval of Glybera

The scientists who led the team that developed Glybera, the first gene therapy drug approved for use in the Western world, provide a fascinating first-person account of their pioneering work in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

16 May 2013

Scientists develop eco-friendly flame retardants with dual effects

Amid concerns over the potential health effects of existing flame retardants for home furniture, fabrics and other material, scientists are reporting development of an "exceptionally" effective new retardant that appears safer and more environmentally friendly.

16 May 2013

Hydrogel scaffolds can help evaluate how engineering nanoparticles interact with cells

A class of water-loving, jelly-like materials with uses ranges ranging from the mundane, such as superabsorbent diaper liners, to the sophisticated, such as soft contact lenses, could be tapped for a new line of serious work: testing the biological effects of nanoparticles now being eyed for a large variety of uses.

16 May 2013

Antibiotic stewardship program using MALDI Biotyper reduces hospital stays, overall costs

A co-author of a groundbreaking study documenting reductions in patient length of stay and overall costs from implementation of an antibiotic stewardship program using Bruker's MALDI Biotyper will share her observations at a Bruker symposium to be held during the upcoming American Society for Microbiology General Meeting.

16 May 2013

Researchers see potential in deploying Akkermansia bacteria to understand and treat obesity

A dominant and useful bacterium called Akkermansia muciniphila is present in the intestinal system of all humans, from babies to the elderly. This microorganism is found in the intestinal mucus layer that protects against intruders.

16 May 2013

Breathing motor vehicle emissions triggers change in HDL cholesterol

Academic researchers have found that breathing motor vehicle emissions triggers a change in high-density lipoprotein cholesterol, altering its cardiovascular protective qualities so that it actually contributes to clogged arteries.

16 May 2013

Researchers demonstrate how EGF accelerates division of cell nucleus

Biologists at Heidelberg University have discovered new approaches for the treatment of cancer. They investigated how a special signalling molecule, the epidermal growth factor (EGF), stimulates the separation of chromosomes in the cell. The researchers were able to demonstrate that EGF accelerates the division of the cell nucleus, i.e. mitosis, as well as boosts precision in chromosome segregation.

15 May 2013

Soligenix starts first clinical study for development of SGX203 for pediatric Crohn's disease

Soligenix, Inc., a clinical stage biopharmaceutical company focused on developing products to treat inflammatory diseases and biodefense countermeasures where there remains an unmet medical need, announced today that it has initiated the first clinical study for development of SGX203 (oral beclomethasone 17,21-dipropionate or oral BDP) for the treatment of pediatric Crohn's disease.

15 May 2013

Laboratory News and Research

Thioridazine works by weakening staphylococcal cell wall, new study reveals

New LAMP malaria test to improve diagnosis for imported UK cases

Columbia University signs licensing agreement with Varian Medical Systems for novel imaging software

Weekend reading: Volunteers in the battle with heart disease; Psychiatry without medication; Owning your genes

Viewpoints: When a doctor should keep quiet; 2 views of hospital pricing; Stem cell 'snake oil'

New research reveals how endothelium maintains highly efficient barrier function

UCSF researchers create first functioning human thymus tissue from embryonic stem cells

Research shows new neural circuits arise when hippocampus is disabled

UT Arlington physicist develops new tool to map, track interactions between neurons inside the brain

RIKEN researchers visualize memory formation for first time in zebrafish

Novel cell sorting enhancement to MoFlo Astrios platform to be introduced by Beckman Coulter Life Sciences at CYTO 2013

Transgenomic launches new mutation detection test for patients with metastatic colorectal cancer

Scientists reveal inside story of European regulatory review and approval of Glybera

Scientists develop eco-friendly flame retardants with dual effects

Hydrogel scaffolds can help evaluate how engineering nanoparticles interact with cells

Antibiotic stewardship program using MALDI Biotyper reduces hospital stays, overall costs

Researchers see potential in deploying Akkermansia bacteria to understand and treat obesity

Breathing motor vehicle emissions triggers change in HDL cholesterol

Researchers demonstrate how EGF accelerates division of cell nucleus

Soligenix starts first clinical study for development of SGX203 for pediatric Crohn's disease

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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