Leptin News and Research

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Leptin is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The ''Ob(Lep)'' gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.

Novel therapy using nitric oxide may be an efficient and safe way to treat multiple metabolic diseases

A novel therapy developed at the University of Alabama at Birmingham ameliorates obesity and Type 2 diabetes in mice fed a high-fat diet.

29 Apr 2022

Understanding the Choice Between Individual Versus Social Housing Mice and Its Impact On Research

In this interview, Steffen van Heijningen discusses the differences between individual and social housing of mice and how housing conditions can impact the research.

From Noldus Information Technology 26 Apr 2022

The effects of prolonged sleep restriction on energy intake, energy expenditure, and regional fat storage in healthy individuals

A new study provides insights into how experimentally-induced sleeplessness affects body fat when the subject is provided access to food.

1 Apr 2022

New research project aims to investigate the different 'languages' used by viruses

The different "languages" used by viruses will be investigated by a new research project at the University of Exeter.

18 Mar 2022

Study uncovers new clues about the cellular processes that can lead to androgen deficiency

A laboratory study at the Miller School of Medicine's Desai Sethi Urology Institute has uncovered new clues about the cellular processes that can lead to deficiencies of androgens (male hormones) such as testosterone.

4 Mar 2022

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

In a new study, researchers evaluated the single-cell transcriptomes from bronchiolar lavage in three adult cohorts comprising of obese and non-obese SARS-CoV-2 patients.

24 Jan 2022

DPP4 protein: The connection between severe COVID-19 and diabetes

Researchers explore the relationship between DPP4 and diabetes targets in the management of COVID-19.

17 Jan 2022

Blocking an enzyme activity inside fat cells can reduce obesity in mice

Blocking the activity of an enzyme inside fat cells can decrease obesity and related health disorders in mice, according to new research led by the University of Michigan Life Sciences Institute.

17 Jan 2022

New project aims to study how bacterial defenses influence the spread of mobile genetic elements

A major new project will investigate how bacterial defenses influence the spread of segments of DNA called mobile genetic elements (MGEs) between bacteria.

13 Jan 2022

Role of leptin in immune modulation and pathophysiology of COVID-19

A recent review paper in the journal Frontiers in Physiology discusses the role of leptins in infection with SARS-CoV-2 that triggered the ongoing COVID-19 pandemic.

13 Jan 2022

Newly discovered hormone may play a key role in the development of type 1 and type 2 diabetes

A newly discovered hormone named fabkin helps regulate metabolism and may play an important role in the development of both type 1 and type 2 diabetes, according to research led by the Sabri Ülker Center for Metabolic Research at Harvard T.H. Chan School of Public Health.

12 Dec 2021

New hormone may play a key role in the development of type 1 and type 2 diabetes

8 Dec 2021

Fat-secreted molecule may cancel out the effects of common breast cancer treatment

Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study led by researchers from the Johns Hopkins Kimmel Cancer Center.

9 Nov 2021

UTSW scientists discover a possible strategy to combat obesity

UT Southwestern scientists may have identified a method of safely mimicking the weight-loss benefits of a plant compound that – despite its harmful side effects – hold critical answers to developing therapies for obesity.

2 Nov 2021

Factors contributing to a weak antibody response to the Pfizer COVID-19 vaccine

A new study discusses risk factors for the failure of seroconversion following full vaccination with the COVID-19 Pfizer vaccine.

18 Oct 2021

Researchers identify protein that plays a key role in how the brain regulates appetite and metabolism

Researchers from the Okinawa Institute of Science and Technology Graduate University have identified a protein that plays a key role in how the brain regulates appetite and metabolism.

18 Oct 2021

Asthmatic children who are overweight or obese less likely to respond to inhaled steroids

Asthmatic children are less likely to respond to inhaled steroid medication if they are overweight or obese, and this leads to more frequent asthma attacks, according to research presented at the 'virtual' European Respiratory Society International Congress today (Wednesday).

8 Sep 2021

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