Leptin News and Research

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Leptin is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. It is one of the most important adipose derived hormones. The ''Ob(Lep)'' gene (Ob for obese, Lep for leptin) is located on chromosome 7 in humans.

Researchers reveal the role of hypothalamic astrocytes in obesity-related hypertension

Researchers have succeeded for the first time in demonstrating the role of hypothalamic astrocytes in obesity-related hypertension.

15 Jun 2021

Potential leptin therapy for nonalcoholic steatohepatitis

In those with fatty liver disease, a person's fat goes to their liver instead of their fat tissue, either because of an absence of fat depots, which is seen in the rare genetic disease lipodystrophy, or because the depots are too full, which is seen in people with obesity.

7 Jun 2021

New study advances knowledge about the link between obesity-associated inflammation and cancer

A review study led by Maria D. Sanchez-Pino, PhD, an assistant research professor in the departments of Interdisciplinary Oncology and Genetics at LSU Health New Orleans' School of Medicine and Stanley S. Scott Cancer Center, advances knowledge about the connection between obesity-associated inflammation and cancer.

28 May 2021

Reduced levels of leptin are linked to poor vaccine responses in general population

Reduced levels of a metabolic hormone known as leptin is linked to poor vaccine antibody responses in the general population, a University of Queensland study has found.

24 May 2021

Girls more likely to develop metabolic alterations associated with obesity than boys

A study of 92 adolescents conducted in Brazil suggests girls are more likely than boys to develop metabolic alterations associated with obesity, such as high blood pressure and excessive blood levels of cholesterol and triglycerides (dyslipidemia).

12 May 2021

Machine learning approach helps study human hypothalamus at the single-cell level

Human brain organoids are remarkable platforms for modeling features of human brain development and diseases.

11 May 2021

Researchers establish new link between high BMI and breast cancer survival rates

Medical researchers at Flinders University have established a new link between high body mass index (BMI) and breast cancer survival rates - with clinical data revealing worse outcomes for early breast cancer (EBC) patients and improved survival rates in advanced breast cancer (ABC).

30 Apr 2021

Obesity and high-salt diet pose bigger, seemingly synergistic cardiovascular risks for females

Obesity and a high-salt diet are both bad for our hearts but they are bigger, seemingly synergistic risks for females, scientists report.

29 Apr 2021

Study shows how leptin suppresses appetite

Since the discovery of leptin in the 1990s, researchers have wondered, how does leptin, a hormone made by body fat, suppress appetite? Despite tremendous gains in the intervening three decades, many questions still remain.

7 Apr 2021

Mice study provides insight into the beneficial effects of selenium supplementation

Adding the nutrient selenium to diets protects against obesity and provides metabolic benefits to mice, according to a study published today in eLife.

30 Mar 2021

Researcher get federal grant to study how gut microbiota and inflammation promote metabolic syndrome

Dr. Andrew Gewirtz, a professor in the Institute for Biomedical Sciences at Georgia State University, has received a four-year federal grant just over $2 million to study how inflammation and altered gut microbiota, the microorganisms living in the intestine, influence the development of a group of diseases referred to as metabolic syndrome.

18 Mar 2021

Study reveals key mechanism by which exercise promotes immunity, strengthens bones

Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) have identified the specialized environment, known as a niche, in the bone marrow where new bone and immune cells are produced.

25 Feb 2021

Leptin plays a strong role in controlling the body weight of children

Young children of African ancestry are more at risk of developing obesity if they possess a genetic variant that reduces their ability to produce the hormone leptin.

23 Nov 2020

Inflammatory factors that aggravate COVID-19 may come from adipose tissue

There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals.

20 Nov 2020

Leptin News and Research

Further Reading

Researchers reveal the role of hypothalamic astrocytes in obesity-related hypertension

Potential leptin therapy for nonalcoholic steatohepatitis

New study advances knowledge about the link between obesity-associated inflammation and cancer

Reduced levels of leptin are linked to poor vaccine responses in general population

Girls more likely to develop metabolic alterations associated with obesity than boys

Machine learning approach helps study human hypothalamus at the single-cell level

Researchers establish new link between high BMI and breast cancer survival rates

Obesity and high-salt diet pose bigger, seemingly synergistic cardiovascular risks for females

Study shows how leptin suppresses appetite

Mice study provides insight into the beneficial effects of selenium supplementation

Researcher get federal grant to study how gut microbiota and inflammation promote metabolic syndrome

Study reveals key mechanism by which exercise promotes immunity, strengthens bones

Leptin plays a strong role in controlling the body weight of children

Inflammatory factors that aggravate COVID-19 may come from adipose tissue

Dusp8 protein has regulatory effects on hypothalamic insulin sensitivity

America’s obesity epidemic threatens effectiveness of any COVID vaccine

Researchers identify differences in clinical features of non-obese patients with NAFLD

Elevated leptin levels may explain why COVID-19 is so dangerous for people with obesity

Study shows how leptin regulates the presence of neurons in fat

Fasting-mimicking diet along with hormone therapy could help treat breast cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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