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Testing treatments for bone cancer may get easier with enhanced 3D-printed scaffolds

Testing treatments for bone cancer tumors may get easier with new enhancements to sophisticated support structures that mimic their biological environment, according to Rice University scientists.

9 Feb 2017

Scientists identify structure of androgenic receptor essential to fight against prostate cancer

A team led by researchers of the Institute of Biomedicine of the University of Barcelona and the Research Institute of the Hospital de la Santa Creu i Sant Paushows for the first time, the three-dimensional structure of the homodimeric androgen receptor ligand-binding domain, a structure that eluded researchers for years.

6 Feb 2017

TSRI chemists create new technique for constructing chiral drug molecules

Chemists at The Scripps Research Institute (TSRI) have invented a new technique for constructing chiral drug molecules.

3 Feb 2017

‘Love hormone’ from insects could be used as drug lead to prevent uterine contractility in preterm labour

In a recent study published in "Scientific Reports", an international team of researchers led by MedUni Vienna report that an oxytocin-like neuropeptide ("inotocin") exhibited a specific pharmacological profile for the human receptors of oxytocin (known as the "love hormone") and vasopressin.

1 Feb 2017

New immunotherapy active against mucosal melanoma and improves survival for bladder cancer patients

Clinical trials of a new immunotherapy, pembrolizumab, have shown that it prolongs life significantly for patients with bladder cancer and is active against a rare sub-type of melanoma, called mucosal melanoma.

30 Jan 2017

Advanced NMR-based methods for studying RNPs and drug design

Nuclear magnetic resonance (NMR) spectroscopy is a powerful analytical tool widely used in chemical research to investigate the structure and dynamics of molecules.

From Bruker BioSpin - NMR, EPR and Imaging 24 Jan 2017

TSRI scientists develop new method to enhance drug discovery and protein research

A team led by scientists at The Scripps Research Institute (TSRI) has developed a versatile new method that should enhance the discovery of new drugs and the study of proteins.

20 Jan 2017

Scientists develop 3-D organoid to unravel immune response during infection

What if you could design an adaptable, biomaterials-based model of an organ to track its immune response to any number of maladies, including cancer, transplant rejection and the Zika virus? The lab of Ankur Singh, assistant professor in the Sibley School of Mechanical and Aerospace Engineering, has asked - and begun to answer - that very question.

6 Jan 2017

How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body.

4 Jan 2017

A new strategy to fight prostate cancer

A new study led by scientists from the Florida campus of The Scripps Research Institute (TSRI) sheds light on a signaling circuit in cells that drives therapy resistance in prostate cancer.

30 Dec 2016

Optical fibers can identify and control neuroreceptors to rapidly inhibit chronic pain

Pain serves as a valuable warning signal, but when it becomes chronic, pain should be considered as a real disease.

21 Dec 2016

Scientists discover how COPD patients' lungs lose ability to repair damages

In chronic obstructive pulmonary disease (COPD), the patients' lungs lose their ability to repair damages on their own.

16 Dec 2016

New Forsyth study provides new foundation for fighting Sjögren's syndrome

Sjögren's syndrome is the second most common autoimmune disease affecting four million Americans--yet treatments are limited due to a lack of knowledge about its causes.

14 Dec 2016

Study suggests new approach to treat white blood cells of sepsis patients

New research findings published in the Journal of Leukocyte Biology, suggest that treating the white blood cells of sepsis patients with antibodies that block programmed cell death-1 (PD-1) and programmed cell death ligand (PD-L1) molecules may restore their function and ultimately their ability to eradicate deadly bacteria.

1 Dec 2016

Researchers develop efficient computational method to create new drugs

Researchers of the University of Barcelona have developed a more efficient computational method to identify new drugs.

1 Dec 2016

Tiny, glowing crystals could be powerful new tool to detect and clean contaminated water sources

Tiny, glowing crystals designed to detect and capture heavy-metal toxins such as lead and mercury could prove to be a powerful new tool in locating and cleaning up contaminated water sources.

29 Nov 2016

Melanoma drug offers considerable added benefit for patients with advanced NSCLC

Pembrolizumab was initially introduced for the treatment of melanoma. Since July 2016, the monoclonal antibody has also been available for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) in adults whose tumours express the T-cell receptor ligand PD-L1 and who have received a prior chemotherapy regimen.

22 Nov 2016

Compugen program shows potential for development of new immunotherapy treatments for solid tumors

Compugen Ltd., a leading predictive drug discovery company, today presented new data for its preclinical CGEN-15029 program demonstrating the potential for the development of new cancer immunotherapy treatments for solid tumors, including the potential for drug combination with current immune checkpoint blockers.

11 Nov 2016

Novel purification process for camelid heavy chain antibodies

KNAUER Wissenschaftliche Geräte GmbH and 3B Pharmaceuticals GmbH today announced the successful completion of a federal grant program exploiting the potential of camelid antibodies.

From KNAUER Wissenschaftliche Geräte GmbH 9 Nov 2016

Pathogenicity of fungus in plants could provide clinical information about respiratory diseases

Researchers from UPM id reveal how mould from humidity caused by rotting fruits and vegetables unfolds a surprising strategy to infect plants.

17 Oct 2016