Liver News and Research

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University of Cambridge forms new spin-out company to supply hIPSC-derived cells

The potential therapeutic applications of stem cells - such as regenerating damaged tissues or organs - have generated a great deal of interest over the past decade. While these types of applications are exciting, it is a long journey from lab to clinic. The most immediate impact of stem cells on human health will most likely come from their use in the development of new drugs.

3 Nov 2012

UC Irvine, Cal State Fullerton partner to help reduce cancer disparities in Orange County

Researchers from UC Irvine's Chao Family Comprehensive Cancer Center and California State University, Fullerton's Health Promotion Research Institute have formed a partnership to help reduce cancer disparities in Orange County.

2 Nov 2012

Developing comorbid conditions post-liver transplant reduces donor quality of life

Researchers in Japan report that health-related quality of life (HRQOL) for donors following living donor liver transplantation (LDLT) was better than the general Japanese population (the norm). This study—one of the largest to date—found that donors who developed two or more medical problems (co-morbidities) after donation had significantly decreased long-term HRQOL.

2 Nov 2012

Malarial drug shows promise in stopping breast cancer

A malarial drug is showing promise in stopping breast cancer before it starts, Mason researchers are discovering during a clinical trial.

2 Nov 2012

Study shows reduced risk of liver-related mortality in African American women with HIV/HCV

A new study shows that African American women coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) are less likely to die from liver disease than Caucasian or Hispanic women. Findings in the November issue of Hepatology, a journal published by Wiley on behalf of the American Association for the Study of Liver Diseases, indicate that lower liver-related mortality in African American women was independent of other causes of death.

1 Nov 2012

Nitisinone treatment effectively prevents tyrosinemia in children

A consortium of Quebec researchers coordinated by the Medical Genetics Service of the Sainte-Justine UHC has just published the findings of a 25-year study on the treatment of tyrosinemia, a life-threatening liver disease of genetic origin, which is screened at birth in the province of Quebec, where it is much more frequent than anywhere else in the world.

1 Nov 2012

Scientists discover first selective inhibitors of DAGL enzymes

Scientists at The Scripps Research Institute (TSRI) have discovered the first selective inhibitors of an important set of enzymes. The new inhibitors, and chemical probes based on them, now can be used to study the functions of enzymes known as diacylglycerol lipases (DAGL), their products, and the pathways they regulate.

1 Nov 2012

Recurrence risk can be identified before hepatectomy

Patients who are likely to experience disease recurrence after undergoing hepatectomy for hepatocellular carcinoma can be identified by factors that are available preoperatively, indicate the results of a Hong Kong study.

31 Oct 2012

African American women coinfected with HIV and HCV less likely to die from liver disease than Caucasian or Hispanic women

31 Oct 2012

Substantial number of cancer survivors experience poor mental or physical health years after cancer

Survivors of many common cancers enjoy a mental and physical health-related quality of life equal to that of adults who have not had cancer, but survivors of other cancers are in poorer health, according to results published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

31 Oct 2012

More than one third of U.S. cancer survivors report poor physical or mental health

Beating cancer is just the first step. More than one third of the 12.6 million cancer survivors in the United States have physical or mental problems that put their overall health in jeopardy, according to researchers at Wake Forest Baptist Medical Center.

31 Oct 2012

Radiation therapy protocol deviations associated with increased risk of treatment failure and overall mortality

Radiation therapy protocol deviations in clinical trials are associated with increased risk of treatment failure and overall mortality, according to a study entitled, “Radiotherapy Protocol Deviations are Associated with Inferior Clinical Outcomes: A Meta-analysis of Cooperative Group Clinical Trials” to be presented today at the 54th annual meeting of the American Society for Radiation Oncology (ASTRO) in Boston, MA.

30 Oct 2012

Sequana Medical announces CE mark approval of alfapump for patients with malignant ascites

Sequana Medical is pleased to announce that it has received CE mark approval for use of its alfapump system in patients with ascites caused by cancer (malignant ascites).

30 Oct 2012

CINJ visiting scientist receives International - U.S. Annual Meeting Scientific Abstract Award

Songbing Qin, MD, a visiting scientist to The Cancer Institute of New Jersey, has received the International - U.S. Annual Meeting Scientific Abstract Award at the 54th Annual Meeting of the American Society for Radiation Oncology (ASTRO) being held in Boston this week.

30 Oct 2012

Oxidative stress occurs in genetic models of alpha-1-antitrypsin deficiency

A team of researchers under the direction of Dr. Jeffrey Teckman in the Department of Pediatrics at St. Louis University, have demonstrated that oxidative stress occurs in a genetic model of alpha-1-antitrypsin deficiency.

30 Oct 2012

BioRx added to Zemaira distribution network

BioRx, a national specialty pharmacy and infusion services provider, has been added to the limited distribution network for Zemaira [alpha-1 proteinase inhibitor (human)]. Zemaira is indicated for chronic augmentation and maintenance therapy in individuals with alpha1-antitrypsin (AAT) deficiency and clinical evidence of emphysema.

30 Oct 2012

Post-hepatectomy mortality unexpectedly high

In-hospital mortality rates for liver resection patients may underestimate true, postoperative mortality by 50%, show the findings of a national study.

29 Oct 2012

Isis commences ISIS-FXIRx Phase 2 study in knee replacement surgery patients

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 2 comparator-controlled study evaluating ISIS-FXIRx in patients undergoing knee replacement surgery, also referred to as total knee arthroplasty (TKA).

29 Oct 2012

High-intensity interval training makes middle-aged people smarter

High-intensity interval training makes middle-aged people not only healthier but smarter, showed a Montreal Heart Institute (MHI) study led by Dr. Anil Nigam of the MHI and University of Montreal, in collaboration with the Montreal Geriatric University Institute.

29 Oct 2012

Chemists' innovation may be a better model for disease diagnostic kits

When someone develops liver cancer, the disease introduces a very subtle difference to their bloodstream, increasing the concentration of a particular molecule by just 10 parts per billion.

29 Oct 2012

Liver News and Research

University of Cambridge forms new spin-out company to supply hIPSC-derived cells

UC Irvine, Cal State Fullerton partner to help reduce cancer disparities in Orange County

Developing comorbid conditions post-liver transplant reduces donor quality of life

Malarial drug shows promise in stopping breast cancer

Study shows reduced risk of liver-related mortality in African American women with HIV/HCV

Nitisinone treatment effectively prevents tyrosinemia in children

Scientists discover first selective inhibitors of DAGL enzymes

Recurrence risk can be identified before hepatectomy

African American women coinfected with HIV and HCV less likely to die from liver disease than Caucasian or Hispanic women

Substantial number of cancer survivors experience poor mental or physical health years after cancer

More than one third of U.S. cancer survivors report poor physical or mental health

Radiation therapy protocol deviations associated with increased risk of treatment failure and overall mortality

Sequana Medical announces CE mark approval of alfapump for patients with malignant ascites

CINJ visiting scientist receives International - U.S. Annual Meeting Scientific Abstract Award

Oxidative stress occurs in genetic models of alpha-1-antitrypsin deficiency

BioRx added to Zemaira distribution network

Post-hepatectomy mortality unexpectedly high

Isis commences ISIS-FXIRx Phase 2 study in knee replacement surgery patients

High-intensity interval training makes middle-aged people smarter

Chemists' innovation may be a better model for disease diagnostic kits

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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