Metabolites News and Research

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Severe COVID-19 complications linked to gut barrier breakdown

A new study claims that severe COVID-19 is caused by a positive feedback loop triggered by systemic inflammation and mediated by abnormal gut permeability. This finding could potentially help open up new avenues of treatment.

18 Nov 2020

Study reveals the metabolic signaling mechanisms that regulate function of eTreg cells

Effector regulatory T cells (eTreg cells) are a specialized subset of white blood cells that keep the immune system in check.

17 Nov 2020

Short bursts of exercise elicit widespread changes in the body's levels of metabolites

Short bursts of physical exercise induce changes in the body's levels of metabolites that correlate to, and may help gauge, an individual's cardiometabolic, cardiovascular and long-term health, a study by Massachusetts General Hospital has found.

16 Nov 2020

Metabolic biomarkers could predict COVID-19 severity

A new study suggests that metabolic biomarkers could possibly predict the severity of COVID-19 in patients.

16 Nov 2020

Study confirms link between gut microbiota and Alzheimer's disease

Alzheimer's disease is the most common cause of dementia. Still incurable, it directly affects nearly one million people in Europe, and indirectly millions of family members as well as society as a whole.

16 Nov 2020

MTT procedure improves gastrointestinal, behavioral symptoms in ASD children

According to the Centers for Disease Research, 1 in 54 children is diagnosed with autism spectrum disorder (ASD) each year, and the number has been rising.

15 Nov 2020

A detailed review of plant natural products to combat antibiotic-resistant pathogens

Scientists have compiled the first comprehensive review of plant natural products that play a role in antibacterial activity, to serve as a guide in the search for new drugs to combat antibiotic-resistant pathogens.

12 Nov 2020

Optical technique could transform accuracy and detection of biomechanical alterations of cells

Scientists have developed an optical elastography technique that could revolutionize the accuracy and ease to which health professionals can detect biomechanical alterations of cells and tissues.

11 Nov 2020

COVID-19-associated pulmonary aspergillosis caused by aspergillus fumigatus

A new study published on the preprint server bioRxiv in November 2020 discusses the characteristics of COVID-19 associated pulmonary aspergillosis (CAPA).

10 Nov 2020

ERC Synergy project explores causes of drug tolerance in intractable fungal infections

Over the next six years, research groups at Charité - Universitätsmedizin Berlin and Tel Aviv University will study how invasive fungal pathogens are able to evade treatments and develop tolerance to antifungal drugs.

10 Nov 2020

Study: Blocking energy pathway helps reduce graft-versus-host disease

MUSC Hollings Cancer Center researchers identified that blocking an alternative energy pathway for T-cells after hematopoietic stem cell transplant helps reduce graft-versus-host disease (GVHD) in an animal model of leukemia.

5 Nov 2020

Researchers to explore the role of gut microbes in childhood celiac disease

Boston College Assistant Professor of Biology Emrah Altindis has received a three-year, $300,000-grant from the G. Harold and Leila Y. Mathers Foundation for research into childhood celiac disease.

3 Nov 2020

Remdesivir metabolite GS-441524 inhibits SARS CoV-2 in mouse model, finds study

This new study titled, "Remdesivir Metabolite GS-441524 Efficiently Inhibits SARS-CoV-2 Infection in Mouse Model," was released online as a preprint on the bioRxiv* server, prior to undergoing the peer-review process.

2 Nov 2020

University of Illinois Urbana-Champaign professor wins $4.5 million for breast cancer research and therapy

University of Illinois Urbana-Champaign Professor of Molecular and Integrative Physiology Erik Nelson has won a $4.5M Era of Hope Scholar Award from the United States Department of Defense (DoD) Breast Cancer Research Program (BCRP).

30 Oct 2020

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Breast cancer is the leading cause of cancer-related death among the female population globally, despite the ever-growing technology of early detection.

From Bruker BioSpin - NMR, EPR and Imaging 30 Oct 2020

Medicinal plant stops the growth of breast cancer cells, shows research

A plant which had previously been dismissed as not being medically useful, could prove to be a hero in disguise, after scientists discovered it not only stops the growth of breast cancer cells but does not affect normal cells - a potential first for future cancer chemotherapy treatment.

30 Oct 2020

CN Bio announces launch of drug metabolism and safety toxicity testing services

CN Bio, a leading 3D cell culture company, that has developed single and multi-organ microphysiological systems to improve the accuracy and efficiency of drug discovery, today announced the commercial launch of its Drug Metabolism and Safety Toxicity Testing Services.

28 Oct 2020

Study findings could lead to a rapid, cost-effective screening tool for COVID-19

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

27 Oct 2020

Dietary 1H-NMR “Fingerprints” Could Help Fight Against Chronic Disease

Metabolic urine profiling could provide an approach to understand what people have been eating, without them needing to tell you. Here, researchers from Imperial College London, Prof Gary Frost, Prof Elaine Holmes, and Dr. Isabel Garcia-Perez, explain why this could be invaluable to both nutritional research and individuals.

From Bruker BioSpin - NMR, EPR and Imaging 27 Oct 2020

Tryptophan found in turkeys can accelerate intestinal healing in people with celiac disease

People with celiac disease may find themselves more comfortable with extra Thanksgiving turkey dinners.An international team of researchers led by McMaster University has found that tryptophan, an amino acid present in high amounts in turkey, along with some probiotics, may help them heal and respond better to a gluten-free diet.

22 Oct 2020

Metabolites News and Research

Severe COVID-19 complications linked to gut barrier breakdown

Study reveals the metabolic signaling mechanisms that regulate function of eTreg cells

Short bursts of exercise elicit widespread changes in the body's levels of metabolites

Metabolic biomarkers could predict COVID-19 severity

Study confirms link between gut microbiota and Alzheimer's disease

MTT procedure improves gastrointestinal, behavioral symptoms in ASD children

A detailed review of plant natural products to combat antibiotic-resistant pathogens

Optical technique could transform accuracy and detection of biomechanical alterations of cells

COVID-19-associated pulmonary aspergillosis caused by aspergillus fumigatus

ERC Synergy project explores causes of drug tolerance in intractable fungal infections

Study: Blocking energy pathway helps reduce graft-versus-host disease

Researchers to explore the role of gut microbes in childhood celiac disease

Remdesivir metabolite GS-441524 inhibits SARS CoV-2 in mouse model, finds study

University of Illinois Urbana-Champaign professor wins $4.5 million for breast cancer research and therapy

High Throughput Identification and Quantification of Breast Cancer With NMR-Based Metabolomics

Medicinal plant stops the growth of breast cancer cells, shows research

CN Bio announces launch of drug metabolism and safety toxicity testing services

Study findings could lead to a rapid, cost-effective screening tool for COVID-19

Dietary 1H-NMR “Fingerprints” Could Help Fight Against Chronic Disease

Tryptophan found in turkeys can accelerate intestinal healing in people with celiac disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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