Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Pancreatic cancer and ecoendoscopy

Cancer of the pancreas is the number five in the list of deaths due to cancers in Spain and the third causing deaths due to digestive tumour.

28 Nov 2005

Study finds AKT blocks cancer cell motility

PIn investigating the molecular mechanisms of cancer cell motility - the unique property that enables cancer to spread from its primary origin to other parts of the body - researchers have uncovered a surprising role for the AKT/PKB (protein kinase B) enzyme

26 Nov 2005

FLT-1 blockers, cutting the legs of leukaemia

Leukaemia is characterised by an uncontrolled growth of abnormal blood cells in the bone marrow (BM).

14 Nov 2005

New therapies for prostate cancer

A Dutch study suggested treating prostate cancer patients with higher doses of radiotherapy significantly improved patient outcome and treatment over a five-year period.

3 Nov 2005

Substance found in evening primrose oil inhibits breast cancer gene

Gamma-linolenic acid (GLA), a substance in evening primrose oil and several other plant oils used in herbal medicine, inhibits action of Her-2/neu, a cancer gene that is responsible for almost 30 percent of all breast cancers, Northwestern University researchers report.

3 Nov 2005

Stereotactic body radiation therapy safe and effective way to treat early stage lung cancer in medically inoperable patients

Lung cancer patients with extenuating health problems may have an alternative to traditional radiation therapy through a lung-sparing procedure pioneered at the Indiana University School of Medicine.

1 Nov 2005

Discovery of signaling mechanism may help prevent metastatic melanoma

Researchers at Northwestern University have discovered a key signaling mechanism that may promote the ability of highly aggressive malignant melanoma cells to metastasize, or spread from a primary tumor to distant sites within the body.

1 Nov 2005

First study to confirm the benefit of anti-angiogenic therapy in patients with breast cancer

Results from the first and only interim analysis of an important trial assessing the potential of Herceptin (trastuzumab) to improve disease-free survival (DFS) in HER-2 positive breast cancer patients after adjuvant chemotherapy, have shown that Herceptin affords a significant survival advantage.

1 Nov 2005

Discovery of how communication between cancer cells is controlled

The discovery, by scientists at Monash University and the Sloan Kettering Cancer Centre in New York, of how communication between cancer cells is controlled has promised new treatment options for malignant tumours.

30 Oct 2005

DOS47 scientific paper published in the Journal of Experimental Therapeutics and Oncology

Helix BioPharma announced today the publication of a scientific paper in the Journal of Experimental Therapeutics and Oncology (volume 5, number 2, pp. 93-99), entitled "Urease-induced alkalinization of extracellular pH and its antitumour activity in human breast and lung cancers."

25 Oct 2005

Researchers identify biomarker that indicates a more agressive form of prostate cancer

Staging factors for prostate cancer such as PSA and the Gleason score are extremely useful in predicting prostate cancer outcome," explained Pollack. "However, new biomarkers hold promise in strengthening our ability to predict response to treatment. By identifying the more virulent forms of prostate cancer, we may be able to tailor treatment or develop therapies to target the abnormalities identified."

17 Oct 2005

Cosmopolitan Lifestyle could allay cancer threat

If the cancer-inhibiting properties of red wine don't tempt you, why not try a cosmopolitan, the cranberry-based cocktail made famous by the Sex and the City girls.

17 Oct 2005

Curry spice appears to shut down a protein active in the spread of breast cancer

Curcumin, the main ingredient of turmeric and the compound that gives curry its mustard-yellow color, inhibits metastasis to the lungs of mice with breast cancer, report researchers at The University of Texas M. D. Anderson Cancer Center

16 Oct 2005

Performing a sentinel node biopsy prior to mastectomy and reconstruction gives best results

Altering the standard step-by-step procedure that takes women facing a mastectomy from diagnosis to surgery to reconstruction can improve the process and help in determining if immediate reconstruction is the best course of action, according to new research from the University of North Carolina at Chapel Hill.

10 Oct 2005

Gene variation may play fundamental role in the development and spread of cancer in the body

New research shows that a small gene variation that increases the risk of inherited cancer can also arise during the development of spontaneous, or non-inherited, tumors.

9 Oct 2005

Ubiquitin ligase Rnf6 may be involved in oncogenesis

In a recent study, Dr. Ingolf Bach and colleagues from the University of Massachusetts Medical School, Worcester and the University of Hamburg describe a novel role for the ubiquitin/proteosome protein degradation pathway in the regulation of local actin dynamics in neurons.

3 Oct 2005

Development of aggressive forms of prostate cancer may be influenced by environmental effects that occur early in life

How heavy a man is at the time he is diagnosed with prostate cancer, as well as his history of weight gain, appear to play significant roles in how aggressive his cancer may become, say researchers at the University of Texas M. D. Anderson Cancer Center.

3 Oct 2005

Tumor formation is generated by a complex interaction of both mechanical as well as chemical signals

The relationship between tissue rigidity and tumor formation is fairly well established; however, what is not so well understood is what happens on a molecular level that contributes to such stiffness.

26 Sep 2005

Raf Kinase Inhibitor Protein plays a role in controlling the active movement of cells

University of Illinois at Chicago researchers report that a protein that regulates key signaling pathways in cells also plays a role in controlling the active movement or migration of cells. The finding may suggest new pharmaceutical therapies for treating a variety of diseases, including cancer.

26 Sep 2005

Study points to importance of MYC gene in cancer progression

The cancer gene MYC is among the most commonly overexpressed oncogenes in human cancers. Most human cancers demonstrate high levels of MYC or its biological partners, including those of the breast, ovaries, lung, prostate, and skin, as well as leukemias and lymphomas.

19 Sep 2005

Metastasis News and Research

Further Reading

Pancreatic cancer and ecoendoscopy

Study finds AKT blocks cancer cell motility

FLT-1 blockers, cutting the legs of leukaemia

New therapies for prostate cancer

Substance found in evening primrose oil inhibits breast cancer gene

Stereotactic body radiation therapy safe and effective way to treat early stage lung cancer in medically inoperable patients

Discovery of signaling mechanism may help prevent metastatic melanoma

First study to confirm the benefit of anti-angiogenic therapy in patients with breast cancer

Discovery of how communication between cancer cells is controlled

DOS47 scientific paper published in the Journal of Experimental Therapeutics and Oncology

Researchers identify biomarker that indicates a more agressive form of prostate cancer

Cosmopolitan Lifestyle could allay cancer threat

Curry spice appears to shut down a protein active in the spread of breast cancer

Performing a sentinel node biopsy prior to mastectomy and reconstruction gives best results

Gene variation may play fundamental role in the development and spread of cancer in the body

Ubiquitin ligase Rnf6 may be involved in oncogenesis

Development of aggressive forms of prostate cancer may be influenced by environmental effects that occur early in life

Tumor formation is generated by a complex interaction of both mechanical as well as chemical signals

Raf Kinase Inhibitor Protein plays a role in controlling the active movement of cells

Study points to importance of MYC gene in cancer progression

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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