Myocardial Infarction News and Research

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Arthritis drug caution advised by New Zealand experts

An expert New Zealand committee reviewing the safety of a group of arthritis drugs called COX-2 inhibitors has reinforced UK advice cautioning against their routine use where safe and effective alternatives are available.

21 Dec 2004

Biological clock affects the patterns of heart-rate control in healthy individuals

In a newly reported, first-ever finding, physicists from Boston University and physiologists from Boston’s Brigham and Women’s Hospital (BWH) have found that the body’s biological clock affects the patterns of heart-rate control in healthy individuals independent of sleep/wake cycle or other behavior influences.

21 Dec 2004

Aspirin overlooked as an effective and inexpensive means to reduce cardiovascular disease risk in diabetic women and young adults

Cardiovascular disease risk is extremely high in adults with diabetes. Yet women as well as people under 50 who have diabetes do not use aspirin, despite the fact that aspirin has been found an effective and inexpensive means to reduce risk of first and subsequent heart attack.

20 Dec 2004

Risk of having a heart attack is elevated in the weeks after stopping use of nonsteroidal anti-inflammatory drugs

The risk of having a heart attack is elevated in the weeks after stopping use of nonsteroidal anti-inflammatory drugs, according to an article in the December issue of The Archives of Internal Medicine, one of the JAMA/Archives journals.

13 Dec 2004

Landmark revascularization procedure

The People's Hospital of Beijing University performed a combined revascularization procedure utilizing beating heart bypass surgery, along with transmyocardial revascularization and stem cell implantation.

13 Dec 2004

Greater risk of heart attack associated with Vioxx than Celebrex

In the first epidemiological study designed and executed specifically to determine the heart-attack risk associated with COX-2 inhibitors rofecoxib (Vioxx) and celecoxib (Celebrex), researchers at the University of Pennsylvania School of Medicine found a greater risk of heart attack associated with Vioxx than Celebrex, although neither of the two drugs showed a statistically significant elevated risk of heart attack relative to people who did not use the drugs.

8 Dec 2004

Acetaminophen shows positive cardioprotective effects In heart attack, arrhythmia

Long an under-studied yet widely-used over-the-counter medication, acetaminophen over the last few years is becoming recognized for a range of potential therapeutic uses beyond headache and pain.

16 Nov 2004

Heavy drinking after suffering a heart attack doubles risk of dying

Heavily drinking – or binging – even intermittently, almost doubles a person’s risk of dying after a heart attack, compared to that of a moderate drinker, according, to a first-of-its-kind study, reported at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Dementia patients receiving long-term treatment with Reminyl may be able to stay at home for longer compared

Shire Pharmaceuticals Group has announced that Dementia patients receiving long-term treatment with Reminyl (more than 36 months) may be able to stay at home for longer compared to those receiving treatment for shorter periods of time.

10 Nov 2004

Bretylium tosylate has unique benefits for patients with acute myocardial infarction

An "old" drug has unique benefits for patients with acute myocardial infarction (AMI; commonly known as heart attack), a finding that may contribute to a new understanding of how heart attacks develop, according to an article in the September/October American Journal of Therapeutics.

10 Nov 2004

Reviparin significantly reduces death and repeat heart attacks without increasing the risk of stroke

A major Canadian-led global study has found that an inexpensive anti-blood-clotting drug significantly reduces death and repeat heart attacks without increasing the risk of stroke.

8 Nov 2004

Early reports of thrombosis after insertion of drug-eluting stent

Authors of a research letter in this week’s issue of THE LANCET highlight how the use of drug-eluting stents (DES) may carry a risk of subsequent thrombosis if stenting is accompanied by a withdrawal of antiplatelet therapy.

21 Oct 2004

EMEA statement following withdrawal of Vioxx (rofecoxib)

EU regulators met with the marketing authorisation holder of Vioxx (rofecoxib), Merck Sharp & Dohme, on 4-5 October 2004 at the informal meeting of the European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) held in Scheveningen, The Netherlands.

6 Oct 2004

Receiving a blood transfusion is associated with a greater risk of death for patients with acute coronary syndromes

The use of invasive procedures for treatment of ischemic heart disease has more than tripled in the past 2 decades and is likely to increase in high-risk patients, according to background information in the article.

5 Oct 2004

NIH opens new hospital totally dedicated to clinical research

This new hospital totally dedicated to clinical research — research involving patients — is the most significant addition to the NIH campus in more than 50 years and provides a unique opportunity for scientists, clinicians, and patients to study and conquer both chronic and acute disease in the 21st century.

22 Sep 2004

Coronary angioplasty within 24 hours of medical therapy could improve the outcome for heart-attack patients

Results of a randomised trial in this week’s issue of THE LANCET suggest that a more aggressive approach involving coronary angioplasty soon after anticlotting medical therapy is safe and could offer a better prognosis than more conservative treatment for patients who have had heart attack.

17 Sep 2004

Diabetes mellitus in acute coronary syndromes – worse for women

Diabetes is associated with worse prognosis in patients with myocardial infarction, but if there is a difference between men and women in this respect is less well known.

30 Aug 2004

Early use of aggressive statin therapy may offer some benefit for coronary patients

Statins initiated early after a patient experiences an acute coronary syndrome (ACS) event at dosages above the typical starting dose may help reduce subsequent cardiovascular events, but the high dose regimen used may increase the risk for muscle-related complications, according to the results from the Phase Z portion of the A to Z Trial released on the JAMA website today.

30 Aug 2004

High blood pressure combined with elevated LDL cholesterol more than triples risk of heart attack

High blood pressure and high LDL-cholesterol add up to more than just double trouble for heart health, a Penn State College of Medicine study reports.

30 Aug 2004

No benefit from early PCI/CABG in high risk unstable angina patients

Patients with chest pain are recognized as being at high risk of subsequent adverse cardiac events when their plasma levels of cardiac troponin are elevated as evidence of myocardial damage.

29 Aug 2004

Myocardial Infarction News and Research

Arthritis drug caution advised by New Zealand experts

Biological clock affects the patterns of heart-rate control in healthy individuals

Aspirin overlooked as an effective and inexpensive means to reduce cardiovascular disease risk in diabetic women and young adults

Risk of having a heart attack is elevated in the weeks after stopping use of nonsteroidal anti-inflammatory drugs

Landmark revascularization procedure

Greater risk of heart attack associated with Vioxx than Celebrex

Acetaminophen shows positive cardioprotective effects In heart attack, arrhythmia

Heavy drinking after suffering a heart attack doubles risk of dying

Dementia patients receiving long-term treatment with Reminyl may be able to stay at home for longer compared

Bretylium tosylate has unique benefits for patients with acute myocardial infarction

Reviparin significantly reduces death and repeat heart attacks without increasing the risk of stroke

Early reports of thrombosis after insertion of drug-eluting stent

EMEA statement following withdrawal of Vioxx (rofecoxib)

Receiving a blood transfusion is associated with a greater risk of death for patients with acute coronary syndromes

NIH opens new hospital totally dedicated to clinical research

Coronary angioplasty within 24 hours of medical therapy could improve the outcome for heart-attack patients

Diabetes mellitus in acute coronary syndromes – worse for women

Early use of aggressive statin therapy may offer some benefit for coronary patients

High blood pressure combined with elevated LDL cholesterol more than triples risk of heart attack

No benefit from early PCI/CABG in high risk unstable angina patients

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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