Myopathy News and Research

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The myopathies are neuromuscular disorders in which the primary symptom is muscle weakness due to dysfunction of muscle fiber. Other symptoms of myopathy can include include muscle cramps, stiffness, and spasm. Myopathies can be inherited (such as the muscular dystrophies) or acquired (such as common muscle cramps).

Researchers find long-lasting benefits of gene therapy in dog model of myotubular myopathy

Researchers who previously showed that a gene therapy treatment could save the lives of dogs with a deadly disease called myotubular myopathy—a type of muscular dystrophy that affects the skeletal muscles—have found that the therapy is long-lasting.

7 Jun 2017

Statin medications can cause necrotizing myopathy in some patients

Statin medications, such as Crestor, Lipitor, and other lipid-lowering medications, have been prescribed increasingly in recent years to reduce cardiovascular disease and mortality in high risk individuals.

6 Jun 2017

Scientists locate crucial off-switch for central cell control

As the cell's molecular control center, the mTor kinase regulates cellular metabolism, growth and division. However, in cells affected by pathological change, the regulation goes array.

2 Jun 2017

Scientists identify new gene that prompts muscle stem cells to fuse together

A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues.

1 Jun 2017

Quitting methamphetamine use can prevent drug-related heart damage

Quitting methamphetamine use can reverse the damage the drug causes to the heart and improve heart function in abusers when combined with appropriate medical treatment, potentially preventing future drug-related cases of heart failure or other worse outcomes, according to a study published today in JACC: Heart Failure.

30 May 2017

Study finds no increase in muscle-related symptoms when patients are unaware of taking statin therapy

When patients were unaware they were taking statins there was no reported increase in muscle-related symptoms. But, when patients knew they were taking a statin, they were more likely to report symptoms, a finding consistent with the nocebo effect.

4 May 2017

Researchers achieve new step towards treatment of myotubular myopathy using gene therapy

A team of researchers in France, led by Dr. Ana Buj-Bello (Genethon/Inserm) and teams at the University of Washington and Harvard Medical School in the United States, achieved a new step towards the treatment of myotubular myopathy by gene therapy.

5 Apr 2017

Research findings suggest potential strategies to combat IBMPFD and other degenerative diseases

UCLA researchers have discovered the molecular basis of, and identified potential treatment for, an incurable disease known as inclusion body myopathy, Paget disease with frontotemporal dementia, or IBMPFD.

21 Mar 2017

Gene therapy treats myotubular myopathy in dogs

The rare disorder, called myotubular myopathy, or MTM, affects only males. It causes fatal muscle wasting. Both dogs and boys with the disease typically succumb in early life due to breathing difficulties.

16 Feb 2017

Diet and exercise can help lessen damage caused by malaria, UTA study suggests

The right amount of diet and exercise can help lessen damage to the heart and skeletal muscles brought on by malaria, according to a new UTA study.

12 Jan 2017

HD is myopathy as well as neurodegenerative disease, study suggests

Researchers have discovered that mice with Huntington's disease (HD) suffer defects in muscle maturation that may explain some symptoms of the disorder.

29 Nov 2016

Statins can help prevent first time heart attacks, strokes in adults with cardiovascular risk factors

Cholesterol-lowering drugs help prevent heart attacks and strokes in adults with cardiovascular risk factors such as high cholesterol, high blood pressure, diabetes and smoking, but have not yet had a heart attack or stroke, according to a large-scale analysis of clinical trial data led by the OHSU Pacific Northwest Evidence-Based Practice Center.

14 Nov 2016

CUMC researchers uncover new details of intracellular channel that controls skeletal muscle

Using high-resolution electron microscopy, Columbia University Medical Center researchers have uncovered new details of the structure and function of an intracellular channel that controls the contraction of skeletal muscle.

22 Sep 2016

KIT researchers use high-resolution microscopy to uncover how scavenger cells repair muscle fibers

Everybody knows the burning sensation in the legs when climbing down a steep slope for a long time. It is caused by microruptures in the cell membrane of our muscle fibers.

21 Sep 2016

Consensus paper on atrial cardiomyopathies could be important step forward for research, treatment

The first consensus paper on atrial cardiomyopathies is set to be published simultaneously in EP-Europace, HeartRhythm, and the Journal of Arrhythmia. The key contents are launched today at CARDIOSTIM - EHRA EUROPACE 2016.

13 Jun 2016

Wolff-Parkinson-White patients continue to have atrial fibrillation risk even after catheter ablation, study finds

Patients with Wolff-Parkinson-White syndrome who receive catheter ablation to cure their abnormal heart rhythms are just as likely as non-ablated patients to develop atrial fibrillation no matter what age they receive ablation, according to a new study.

6 May 2016

Myopathy News and Research

Further Reading

Researchers find long-lasting benefits of gene therapy in dog model of myotubular myopathy

Statin medications can cause necrotizing myopathy in some patients

Scientists locate crucial off-switch for central cell control

Scientists identify new gene that prompts muscle stem cells to fuse together

Quitting methamphetamine use can prevent drug-related heart damage

Study finds no increase in muscle-related symptoms when patients are unaware of taking statin therapy

Researchers achieve new step towards treatment of myotubular myopathy using gene therapy

Research findings suggest potential strategies to combat IBMPFD and other degenerative diseases

Gene therapy treats myotubular myopathy in dogs

Diet and exercise can help lessen damage caused by malaria, UTA study suggests

HD is myopathy as well as neurodegenerative disease, study suggests

Statins can help prevent first time heart attacks, strokes in adults with cardiovascular risk factors

CUMC researchers uncover new details of intracellular channel that controls skeletal muscle

KIT researchers use high-resolution microscopy to uncover how scavenger cells repair muscle fibers

Consensus paper on atrial cardiomyopathies could be important step forward for research, treatment

Wolff-Parkinson-White patients continue to have atrial fibrillation risk even after catheter ablation, study finds

Renal risk factors for NA-treated HBV patients identified

Study: Delirium, muscle weakness and other neurological complications of sepsis poorly understood

Berlin researchers identify defects in myotubular myopathy

Could statins treat muscular dystrophy? An interview with Dr. Nick Whitehead and Dr Stan Froehner

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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