Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Use of smokeless tobacco helped hard-to-quit smokers give up their habit

The study, published in the January-March issue of the Journal of Psychoactive Drugs, reports on subjects who were contacted seven years after completion of a smoking cessation program that replaced cigarettes with smokeless tobacco products as a harm-reduction strategy.

7 Apr 2005

SSRI antidepressants "hijack" dopamine signaling as well launching serotonin signals

Researchers have discovered that antidepressant drugs such as Prozac not only affect levels of the neurotransmitter serotonin in the brain, but also "hijack" dopamine signaling as well--causing it to launch serotonin signals. Their findings offer new insight into how Prozac and other "selective serotonin uptake inhibitors" (SSRIs) work and how they might cause problems in patients taking them.

6 Apr 2005

DNA packaging linked with cancer

New laboratory findings at the University of Illinois at Chicago suggest that what lies outside cancer cells is at least as important as the genes inside in explaining a tumor's malignancy.

5 Apr 2005

Men have a four times greater risk than women of developing abdominal aortic aneurysms

Men have a four times greater risk than women of developing abdominal aortic aneurysms, estimated to be the cause of death in 4 percent of people over the age of 65, but the mechanism for this higher incidence has remained unknown.

4 Apr 2005

Gene mutation protecting against malaria linked to prostate cancer incidence in African-American men

Research from the University of Cincinnati College of Medicine suggests that the 60 percent greater incidence of prostate cancer among African-American men is related to a gene mutation developed generations ago in West Africa as nature's way of providing protection from the malaria infection endemic in that part of the world.

4 Apr 2005

Immune cells in the liver travel in the liver's blood vessels with surprising speed and agility

Scientists at New York University School of Medicine viewing the actual journey of immune cells in the liver have found that these cells travel in the liver's blood vessels with surprising speed and agility.

4 Apr 2005

Different antipsychotic medications may have different effects on brain volume in patients with first episode of psychosis

After a first psychotic episode, patients who were treated with an atypical antipsychotic medication had less change in brain volume compared with patients treated with a conventional antipsychotic medication, according to an article in the April issue of Archives of General Psychiatry.

4 Apr 2005

Autistic children found to have abnormal metabolic profile

Autism, a neurodevelopment disorder which has increased tenfold over the last 15 years, now affects 30 of every 10,000 children in the United States.

4 Apr 2005

Airway inflammation boosts infarction damage

Epidemiological studies show that the incidence of cardiovascular disease (CVD) complications are increased in long standing cases of asthma. Historically, the complications are often attributed to the chronic drug therapy used to treat asthma.

3 Apr 2005

Children with autism have a severely abnormal metabolic profile

Chronic biochemical imbalance is often a primary factor in the development of many complex diseases but a possible metabolic basis for autism has not been well explored. Now Arkansas Children's Hospital Research Institute researchers report for the first time that children with autism have a severely abnormal metabolic profile indicating increased vulnerability to oxidative stress.

3 Apr 2005

Not enough evidence that multivitamins prevent infections in the elderly

Role of multivitamins and mineral supplements in preventing infections in elderly people: systematic review and meta-analysis of randomised controlled trials BMJ Online First.

3 Apr 2005

Protein Mnd2 protects chromosome bonds

The protein Mnd2 inhibits premature separation of chromosomes during the formation of gametes. The now published discovery of this regulatory function may help to understand the origin of some common congenital chromosome defects.

30 Mar 2005

Clinical study of mirror neurons provides insights into autism and other disorders

Seeing is doing – at least it is when mirror neurons are working normally. But in autistic individuals, say researchers from the University of California, San Diego, the brain circuits that enable people to perceive and understand the actions of others do not behave in the usual way.

29 Mar 2005

Optical coherence tomography (OCT) can successfully identify the characteristics of coronary plaques

A catheter-based imaging technology called optical coherence tomography (OCT) can successfully identify the characteristics of coronary plaques in patients with various cardiac symptoms. The report from researchers at Massachusetts General Hospital (MGH) will appear in the journal Circulation.

29 Mar 2005

New prostate cancer test

Tessera, Inc., a Seattle-based biomedical company, has released its first product, ProstaMark EPCA (Early Prostate Cancer Antigen), as an Analyte Specific Reagent (ASR) for commercial use in pathology laboratories to assist pathologists in their efforts to determine if cancer is present in the prostate.

28 Mar 2005

KCP protein protects kidneys from damage caused by chronic renal disease and injury

University of Michigan scientists have identified a new and unusual protein that reduces, in laboratory mice, kidney damage caused by chronic renal disease and acute toxic injuries.

28 Mar 2005

Mutated BRCA1 genes cause ovarian cancer indirectly

Mutated BRCA1 genes cause ovarian cancer indirectly, by interfering with the biochemical signals one ovarian cell sends to another, according to a team of researchers led by scientists at the USC/Norris Comprehensive Cancer Center and the Keck School of Medicine of the University of Southern California.

28 Mar 2005

Test that will prevent the needless loss of the thyroid gland in people with the noncancerous condition

New research suggests that physicians can distinguish between a type of thyroid cancer and an identical-looking, non-cancerous thyroid condition by simply determining the activity of three genes.

28 Mar 2005

Docosahexaenoic acid may protect against the accumulation of a protein believed to be linked to Alzheimer's disease

Docosahexaenoic acid (DHA), an omega-3 fatty acid, may protect against the accumulation of a protein believed to be linked to Alzheimer's disease, according to the results of a new study published in the March 30, 2005 issue of The Journal of Neuroscience. The study used Martek DHA, which is produced from microalgae.

23 Mar 2005

Study suggests combination therapy could stop spread, halt growth of melanomas

Researchers at Penn State College of Medicine have identified the mechanism by which the most mutated gene in melanoma, called v599EB-Raf, aids melanoma tumor development demonstrating its importance as a therapeutic target.

22 Mar 2005

Pathology News and Research

Further Reading

Use of smokeless tobacco helped hard-to-quit smokers give up their habit

SSRI antidepressants "hijack" dopamine signaling as well launching serotonin signals

DNA packaging linked with cancer

Men have a four times greater risk than women of developing abdominal aortic aneurysms

Gene mutation protecting against malaria linked to prostate cancer incidence in African-American men

Immune cells in the liver travel in the liver's blood vessels with surprising speed and agility

Different antipsychotic medications may have different effects on brain volume in patients with first episode of psychosis

Autistic children found to have abnormal metabolic profile

Airway inflammation boosts infarction damage

Children with autism have a severely abnormal metabolic profile

Not enough evidence that multivitamins prevent infections in the elderly

Protein Mnd2 protects chromosome bonds

Clinical study of mirror neurons provides insights into autism and other disorders

Optical coherence tomography (OCT) can successfully identify the characteristics of coronary plaques

New prostate cancer test

KCP protein protects kidneys from damage caused by chronic renal disease and injury

Mutated BRCA1 genes cause ovarian cancer indirectly

Test that will prevent the needless loss of the thyroid gland in people with the noncancerous condition

Docosahexaenoic acid may protect against the accumulation of a protein believed to be linked to Alzheimer's disease

Study suggests combination therapy could stop spread, halt growth of melanomas

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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