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New database of PCR primers enables effective detection and identification of RNA viruses

New database of PCR primers enables effective detection and identification of RNA viruses

Scientists at Korea's Daegu Gyeongbuk Institute of Science and Technology scientists have compiled a comprehensive new public database of genetic information to enable the detection and identification of RNA viruses using the polymerase chain reaction assay. [More]
UC researchers uncover obesity-related protein's role in leukemia development

UC researchers uncover obesity-related protein's role in leukemia development

Cancer researchers at the University of Cincinnati College of Medicine have found an obesity-associated protein's role in leukemia development and drug response which could lead to more effective therapies for the illness. [More]
Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

Diamond Blackfan Anemia (DBA) is a condition that is characterized by a failure of the bone marrow to produce red blood cells, congenital abnormalities, and a predisposition to cancer. [More]
Study provides new insights into fundamental characteristics of dendritic cells

Study provides new insights into fundamental characteristics of dendritic cells

Dendritic cells represent an important component of the immune system: they recognize and engulf invaders, which subsequently triggers a pathogen-specific immune response. [More]
Landmark study of virosphere uncovers 1445 viruses

Landmark study of virosphere uncovers 1445 viruses

A landmark study of the virosphere of the most populous animals – those without backbones such as insects, spiders and worms and that live around our houses – has uncovered 1445 viruses, revealing people have only scratched the surface of the world of viruses – but it is likely that only a few cause disease. [More]
UGA researchers developing big data methods to help tackle diseases

UGA researchers developing big data methods to help tackle diseases

The University of Georgia's Ping Ma will use a new grant to crunch big data numbers, not uncommon for a statistics professor. What is unusual is that his work may help save lives. [More]
TUM scientists develop bioinformatics tool that allows worldwide bacterial analysis

TUM scientists develop bioinformatics tool that allows worldwide bacterial analysis

Sequencing data from biological samples such as the skin, intestinal tissues, or soil and water are usually archived in public databases. [More]
New less invasive method could detect bacterial infection in young febrile infants

New less invasive method could detect bacterial infection in young febrile infants

Physicians from Children's Hospital of Michigan, Wayne State University, UC Davis Medical Center and Nationwide Children's Hospital, in collaboration with 19 other pediatric emergency departments around the country, have established a "proof of principle" for measuring patterns of ribonucleic acid (RNA) expression in the bloodstream that can enable clinicians to distinguish bacterial infections from other causes of fever in infants up to two months old. [More]
NUS study reveals RNA editing events play vital role in gastric cancer development

NUS study reveals RNA editing events play vital role in gastric cancer development

A team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore has found that changes in ribonucleic acid (RNA) sequences play a major role in the development of gastric cancer. [More]
New blood test helps identify bacterial infection in infants with fever

New blood test helps identify bacterial infection in infants with fever

A blood test used to measure patterns of ribonucleic acid (RNA) expression can help determine if fever in infants under 2 months old is caused by bacterial or viral infection, according to a preliminary study recently published in the Journal of the American Medical Association. [More]
Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

CRISPR-Cas9 is the go-to technique for knocking out genes in human cell lines to discover what the genes do, but the efficiency with which it disables genes can vary immensely. [More]
Study shows miR-19 helps new neurons in the adult brain stay on track

Study shows miR-19 helps new neurons in the adult brain stay on track

A small stretch of ribonucleic acid called microRNA could make the difference between a healthy adult brain and one that's prone to disorders including schizophrenia. [More]
New research pinpoints specific lncRNA that regulates neural development

New research pinpoints specific lncRNA that regulates neural development

Compared to other mammals, humans have the largest cerebral cortex. A sheet of brain cells that folds in on itself multiple times in order to fit inside the skull, the cortex is the seat of higher functions. It is what enables us to process everything we see and hear and think. [More]
RNA molecular dynamics research provides key insights into new treatments for retroviral diseases

RNA molecular dynamics research provides key insights into new treatments for retroviral diseases

New molecular dynamics research into how RNA folds into hairpin-shaped structures called tetraloops could provide important insights into new treatments for retroviral diseases. [More]
New optimised PCR tests for reliable diagnosis of Zika virus

New optimised PCR tests for reliable diagnosis of Zika virus

DZIF scientists from the University of Bonn have shown that not all conventional Zika virus molecular diagnostic tests for are sufficiently reliable. They developed optimised assays and a control for quantifying viruses in blood and urine. [More]
Researchers identify gene crucial to development of coeliac disease

Researchers identify gene crucial to development of coeliac disease

Coeliac disease is a chronic, immunological disease that is manifested as intolerance to gluten proteins present in wheat, rye and barley. This intolerance leads to an inflammatory reaction in the small intestine that hampers the absorption of nutrients. The only treatment is a strict, life-long, gluten-free diet. [More]
New project aims to prevent complications from drug usage

New project aims to prevent complications from drug usage

If a patient is ill and takes drugs for that illness, these drugs often lead to further illnesses and complications. This affects millions of people throughout the world. [More]
TGen scientists highlight advantages of using RNA-sequencing in precision medicine

TGen scientists highlight advantages of using RNA-sequencing in precision medicine

Uncovering the genetic makeup of patients using DNA sequencing has in recent years provided physicians and their patients with a greater understanding of how best to diagnose and treat the diseases that plague humanity. This is the essence of precision medicine. [More]
Study sheds light on role of RNA editing in cancer

Study sheds light on role of RNA editing in cancer

A new study provides insight on the potential role played by RNA (ribonucleic acid) editing in cancer. The findings, which appear online in the journal Scientific Reports, may further our understanding of an emerging mechanism implicated in tumor initiation and progression, and may thus lead to the development of better treatment options in the future. [More]
Newly identified RNA biomarkers open door for simple, accurate non-invasive test for prostate cancer

Newly identified RNA biomarkers open door for simple, accurate non-invasive test for prostate cancer

A study on non-coding RNA (Ribonucleic Acid) from prostate cancer patients has identified a series of new prostate cancer markers which can be found in urine. Combining these RNA markers into a single test potentially opens the door for simple, accurate non-invasive testing for prostate cancer. [More]
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