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Study provides a hopeful direction for the management of penile squamous cell carcinoma

In a recent multi-center study published in the Journal of the National Cancer Institute, researchers examined the effects of neoadjuvant chemotherapy (NAC) on patients suffering from locally advanced penile squamous cell carcinoma (PSCC).

28 Mar 2024

Researchers discover key drivers behind follicular lymphoma's aggressive transformation

A team led by researchers at Weill Cornell Medicine has identified important drivers of the transformation of a type of blood cancer called follicular lymphoma from a slow-growing form to the aggressive form it takes in some patients.

28 Mar 2024

Cells' built-in stopwatch safeguards mitosis

Each day, hundreds of billions of cells in our body cycle through a period of growth and division. Yet in that time, only about 30 minutes is spent on the critical orchestration of mitosis, when chromosomes are carefully segregated from one parent cell to the next generation of two daughter cells.

28 Mar 2024

Researchers identify increased brain tumor risk with specific contraceptive use

The intracranial meningioma risk associated with progestogen use.

28 Mar 2024

New treatment paradigm focuses on reverting cancer cells to normal state

St. Jude Children's Research Hospital scientists reversed an aggressive cancer, reverting malignant cells towards a more normal state. Rhabdoid tumors are an aggressive cancer which is missing a key tumor suppressor protein.

27 Mar 2024

Novel treatment strategy aims to overstimulate and exhaust cancer cells

Many new drugs inhibit the processes that cancer cells need to divide rapidly. So as to inhibit the cancer as a whole.

27 Mar 2024

Focusing on oncogenic driver mutations and resistance mechanisms in the treatment of NSCLC

Lung cancer is the leading cause of cancer-related death worldwide. Improved understanding of driver mutations of non-small cell lung cancer (NSCLC) has led to more biomarker-directed treatment for patients with advanced stages.

26 Mar 2024

Machine learning identifies key cellular communities in soft tissue sarcoma

Using novel machine learning tools developed at Stanford Medicine, researchers have mapped three distinct cellular configurations that correspond to clinical outcomes for patients with a rare, difficult-to-treat cancer called soft tissue sarcoma.

26 Mar 2024

New genetic system analyzes the underlying mechanisms of CRISPR-based DNA repair outcomes

Since its breakthrough development more than a decade ago, CRISPR has revolutionized DNA editing across a broad range of fields.

26 Mar 2024

UC researchers open Phase 2 clinical trial to test new combination treatment for glioblastomas

A multidisciplinary team of University of Cincinnati Cancer Center researchers have opened a Phase 2 clinical trial to test a new combination treatment for glioblastomas (GBM), the most deadly form of brain tumors.

26 Mar 2024

Bio-Rad launches validated antibodies for rare cell and circulating tumor cell enumeration

Antibodies validated for use with Bio-Rad’s Celselect Slides™ enumeration stain kits to enable immunostaining of captured circulating tumor cells in liquid biopsy samples.

From Bio-Rad Laboratories 26 Mar 2024

Vitamin D receptor presence in breast cancer tumors linked to better survival outcomes

Research identifies vitamin D receptors (VDR) in breast cancer tumors as a promising prognostic marker, linking VDR presence to tumor characteristics, survival outcomes, and potentially informing treatment strategies.

25 Mar 2024

Leveraging cancer therapies to combat tuberculosis

What could cancer teach us about tuberculosis? That's a question Meenal Datta has been chasing since she was a graduate student.

25 Mar 2024

MUTYH gene mutation linked to increased risk of various solid tumors

A gene associated with colorectal cancer appears to also play a role in the development of other solid tumors, according to a study of over 350,000 patient biopsy samples conducted by researchers at the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and Foundation Medicine.

25 Mar 2024

Study investigates the relationship between dietary inflammatory index and stroke risk in US adults

A recent study demonstrated the potential of dietary intervention to reduce stroke incidence by half by reducing systemic inflammation.

25 Mar 2024

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Research highlights the inflammatory impacts of ARDS on the heart, underscoring the role of immune responses in cardiovascular complications from viral infections, including COVID-19, and emphasizes the potential of TNF-α neutralizing therapy to mitigate these effects.

24 Mar 2024

Scientists uncover four proteins that govern the identity of anaplastic large cell lymphoma

A collaboration between scientists from St. Jude Children's Research Hospital and Dana-Farber Cancer Institute uncovered four proteins that govern the identity of anaplastic large cell lymphoma (ALCL), an aggressive form of cancer.

22 Mar 2024

Biomechanical model simulates breast tumor growth

Scientists from Universidad Carlos III de Madrid (UC3M) and Johns Hopkins University (JHU), in the USA, have analyzed the growth of breast tumors from a biomechanical perspective and have created a computational model that simulates the invasion process of cancer cells, depending on the characteristics of the surrounding tissue and cell junctions, among other parameters.

21 Mar 2024

Advancing precision personalized medicine for gastric cancer with 3D bioprinting

Gastric cancer ranks among the most widespread diseases in Asian populations, with South Koreans experiencing the third-highest incidence globally in 2020, as reported by the International Agency for Research on Cancer.

21 Mar 2024

Concomitant pharmacotherapy overcomes immunotherapy challenges in aggressive blood cancer

Researchers at the University of Zurich and the University Hospital Zurich have discovered that a specific mutation in the cancer cells of an aggressive type of blood cancer can prevent novel immunotherapies such as CAR T-cell therapy from working.

21 Mar 2024

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Tumor News and Research

Study provides a hopeful direction for the management of penile squamous cell carcinoma

Researchers discover key drivers behind follicular lymphoma's aggressive transformation

Cells' built-in stopwatch safeguards mitosis

Researchers identify increased brain tumor risk with specific contraceptive use

New treatment paradigm focuses on reverting cancer cells to normal state

Novel treatment strategy aims to overstimulate and exhaust cancer cells

Focusing on oncogenic driver mutations and resistance mechanisms in the treatment of NSCLC

Machine learning identifies key cellular communities in soft tissue sarcoma

New genetic system analyzes the underlying mechanisms of CRISPR-based DNA repair outcomes

UC researchers open Phase 2 clinical trial to test new combination treatment for glioblastomas

Bio-Rad launches validated antibodies for rare cell and circulating tumor cell enumeration

Vitamin D receptor presence in breast cancer tumors linked to better survival outcomes

Leveraging cancer therapies to combat tuberculosis

MUTYH gene mutation linked to increased risk of various solid tumors

Study investigates the relationship between dietary inflammatory index and stroke risk in US adults

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Scientists uncover four proteins that govern the identity of anaplastic large cell lymphoma

Biomechanical model simulates breast tumor growth

Advancing precision personalized medicine for gastric cancer with 3D bioprinting

Concomitant pharmacotherapy overcomes immunotherapy challenges in aggressive blood cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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