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Survey: Racial and ethnic minorities less likely to participate in clinical trials

A survey conducted in one cancer center's catchment area found that while a majority of respondents would be willing to participate in a clinical trial, members of racial and ethnic minority groups were significantly less likely to participate than non-Hispanic whites, according to results presented at the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held September 29-October 2, 2023.

29 Sep 2023

NCI-sponsored cancer clinical trials become more representative of broader patient population

Compared to the year 2000, a greater proportion of NCI-sponsored early-phase clinical trial participants in 2022 were older, from minority racial/ethnic groups, and lived in historically underrepresented regions of the U.S., according to a study presented at the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held September 29-October 2, 2023.

29 Sep 2023

Extending FDA-approved cancer drug indications requires high patient numbers, study finds

Number of patient participants needed for secondary approval of a new cancer drug.

29 Sep 2023

Intranasal vaccine shows promise against COVID variants in hamsters

Intranasal mRNA-LNP vaccines show promise in Syrian golden hamsters, effectively reducing SARS-CoV-2 viral loads and lung pathology. The study suggests potential efficacy against new variants, setting the stage for future research in human applications.

25 Sep 2023

Clinical study launched to test the benefits of immune modulation for hospitalized COVID-19 patients

A clinical trial has launched to test whether early intensive immune modulation for hospitalized COVID-19 patients with relatively mild illness is beneficial.

22 Sep 2023

Inhaled fluticasone furoate falls flat in speeding up COVID-19 recovery, says ACTIV-6 trial

The ACTIV-6 trial investigated the effectiveness of inhaled fluticasone furoate on mild-to-moderate COVID-19 cases and found it did not accelerate recovery or prevent clinical progression compared to a placebo. Interestingly, vaccinated participants showed slightly faster recovery when treated with the drug, while unvaccinated participants did not.

21 Sep 2023

Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

An international clinical trial exploring a new way to treat rare and aggressive gynaecological cancers has launched in Melbourne.

21 Sep 2023

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

A Ludwig Cancer Research study has shown that combining adoptive T cell therapy (ACT) with an innovative, personalized cancer vaccine under development at the Lausanne Branch of the Ludwig Institute for Cancer Research can benefit patients with late-stage, drug-resistant ovarian cancer.

21 Sep 2023

New trial of a preventive HIV vaccine candidate begins in the United States and South Africa

A trial of a preventive HIV vaccine candidate has begun enrollment in the United States and South Africa.

20 Sep 2023

Is the new bivalent COVID-19 vaccine the booster we've been waiting for?

The bivalent COVID-19 vaccine developed by GSK and Sanofi shows promising results with a 64.7% overall effectiveness against symptomatic COVID-19, according to a phase 3 trial. The vaccine performs especially well as a booster, achieving 75.9% efficacy in non-naïve subjects.

17 Sep 2023

NIH launches Phase 1 trial of new investigational universal influenza vaccine

Enrollment in a Phase 1 trial of a new investigational universal influenza vaccine candidate has begun at the National Institutes of Health's Clinical Center in Bethesda, Maryland.

15 Sep 2023

Oto and Lindus Health launch a remote trial to increase patient access to tinnitus therapy

Digital health company Oto and clinical trial start-up Lindus Health today announced the launch of a fully remote, digital trial to increase patient access to life-changing tinnitus therapy.

15 Sep 2023

Nuvectis launches Phase 1a dose escalation clinical trial of new cancer drug

Clinical trials have begun for a drug candidate for hard-to-treat cancers, discovered at the University of Edinburgh and licensed by US biopharmaceutical company Nuvectis Pharma, Inc.

15 Sep 2023

Phase 3 study: The efficacy of monovalent SARS-CoV-2 vaccine with AS03 adjuvant in adults

The effectiveness of a novel monovalent recombinant protein vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Sep 2023

Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Combination immunotherapy with the anti-PD-L1 monoclonal antibody durvalumab and other novel agents outperforms durvalumab alone in the neoadjuvant (pre-surgical) setting for early-stage non-small-cell lung cancer (NSCLC), according to researchers at The University of Texas MD Anderson Cancer Center.

14 Sep 2023

Comparing HIV PrEP medications: Study explores hypertension risk in adults on TAF vs. TDF

The risk of hypertension and statin initiation in adults starting Human Immunodeficiency Virus Pre-exposure prophylaxis.

13 Sep 2023

Idrevadiloride in hypertonic saline improves lung function in people with primary ciliary dyskinesia, trial shows

Primary ciliary dyskenisia (PCD) is a rare genetic disease that causes the tiny hair-like filtration structures in the respiratory tract to stop working.

12 Sep 2023

Oxford University study administers first-ever vaccine against Crimean-Congo hemorrhagic fever

A University of Oxford study has administered a new vaccine against tick-borne virus Crimean-Congo hemorrhagic fever (CCHF) to volunteers for the first time.

11 Sep 2023

Buck Institute receives $3.5 million federal grant to lead clinical trial of ketone intervention in older adults

The Buck Institute for Research on Aging has received a $3.5 million federal grant to lead the first-ever double-blind, randomized, placebo-controlled clinical trial to understand the effects of ketone ester supplementation on frailty, a condition of vulnerability which develops following age-related decline in multiple physiological systems.

11 Sep 2023

CheckMate 227 trial: Nivolumab + ipilimumab shows remarkable six-year survival benefits in metastatic NSCLC

The International Association for the Study of Lung Cancer (IASLC) World Conference on Lung Cancer 2023 in Singapore is set to witness a monumental breakthrough in the field of metastatic non-small cell lung cancer (NSCLC) treatment.

11 Sep 2023

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Drug Trial News

Survey: Racial and ethnic minorities less likely to participate in clinical trials

NCI-sponsored cancer clinical trials become more representative of broader patient population

Extending FDA-approved cancer drug indications requires high patient numbers, study finds

Intranasal vaccine shows promise against COVID variants in hamsters

Clinical study launched to test the benefits of immune modulation for hospitalized COVID-19 patients

Inhaled fluticasone furoate falls flat in speeding up COVID-19 recovery, says ACTIV-6 trial

Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

New trial of a preventive HIV vaccine candidate begins in the United States and South Africa

Is the new bivalent COVID-19 vaccine the booster we've been waiting for?

NIH launches Phase 1 trial of new investigational universal influenza vaccine

Oto and Lindus Health launch a remote trial to increase patient access to tinnitus therapy

Nuvectis launches Phase 1a dose escalation clinical trial of new cancer drug

Phase 3 study: The efficacy of monovalent SARS-CoV-2 vaccine with AS03 adjuvant in adults

Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Comparing HIV PrEP medications: Study explores hypertension risk in adults on TAF vs. TDF

Idrevadiloride in hypertonic saline improves lung function in people with primary ciliary dyskinesia, trial shows

Oxford University study administers first-ever vaccine against Crimean-Congo hemorrhagic fever

Buck Institute receives $3.5 million federal grant to lead clinical trial of ketone intervention in older adults

CheckMate 227 trial: Nivolumab + ipilimumab shows remarkable six-year survival benefits in metastatic NSCLC

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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