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Microbes can manipulate molecular machinery of host cells to influence health

All animals -- from sea sponges to modern-day humans -- evolved in a world already teeming with microbes. These single-celled microorganisms now cover practically every surface of our bodies and are as much a part of our biology as our own tissues and organs.

17 May 2017

Researchers identify new drug target for two common types of myeloid leukemia

University of Georgia researchers, with colleagues from the University of Tokyo, have identified a new drug target for the two most common types of myeloid leukemia, including a way to turn back the most aggressive form of the disease.

17 May 2017

Researchers identify new way to prevent pneumococci from entering the brain

An international team of researchers, led from Karolinska Institutet, has identified two receptors on the cells in the blood vessels of the brain that can be blocked and thereby prevent pneumococci from entering the brain.

17 May 2017

Researchers develop new strategy that can revolutionize HIV vaccine design

Vaccines are an essential tool for preventing and treating serious infectious diseases such as polio, chicken pox and measles. But so far it has not been possible to develop vaccines capable of contributing to the treatment and prevention of chronic infectious diseases such as HIV and hepatitis C.

17 May 2017

Scientists identify gene linked to incurable bowel disorders

A key gene that helps to explain an underlying cause of incurable bowel disorders such as Crohn's disease has been identified by scientists.

17 May 2017

Research identifies 'cell messages' that could help detect early stages of osteoarthritis

New research from the University of Liverpool, published today in the journal 'NPJ Systems Biology and Applications', has identified 'cell messages' that could help identify the early stages of osteoarthritis.

17 May 2017

Study measures increased 'fight or flight' response in young veterans with combat-related PTSD

A new study published this week in the Journal of Physiology finds that young veterans with combat-related post-traumatic stress disorder (PTSD) have an increased 'fight or flight' response during mental stress.

17 May 2017

History of sleep: what was normal?

We used to sleep in two phases, with a first sleep and then a second sleep. Arguably from time immemorial to the nineteenth century, the dominant pattern of sleep in Western societies was biphasic, whereby most preindustrial households retired between 9 and 10pm, slept for 3 to 3 ½ hours during their “first sleep,”

17 May 2017

Researchers identify key inflammatory cells involved in nonalcoholic fatty liver disease

A team of investigators led by Rohit Kohli, MBBS, MS, of Children's Hospital Los Angeles, has identified key inflammatory cells involved in nonalcoholic fatty liver disease.

17 May 2017

Small molecules in saliva show potential for early diagnosis of Alzheimer's disease

Your spit may hold a clue to future brain health. Investigators at the Beaumont Research Institute, part of Beaumont Health in Michigan, are hopeful that their study involving small molecules in saliva will help identify those at risk of developing Alzheimer's disease - a neurologic condition predicted to reach epidemic proportions worldwide by 2050.

17 May 2017

Children surviving chronic health conditions may suffer from brain function issues

Survival rates continue to rise for children living with once-fatal chronic pediatric health conditions. But their survival comes at a cost: many experience long-term neurocognitive deficits.

17 May 2017

‘Disease in a dish’ model pinpoints how defects in blood-brain barrier can cause psychomotor disorder

Scientists for the first time have assembled a "disease in a dish" model that pinpoints how a defect in the blood-brain barrier can produce an incurable psychomotor disorder, Allan-Herndon-Dudley syndrome.

17 May 2017

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

By using induced pluripotent stem cells to create endothelial cells that line blood vessels in the brain for the first time for a neurodegenerative disease, University of California, Irvine neurobiologists and colleagues have learned why Huntington's disease patients have defects in the blood-brain barrier that contribute to the symptoms of this fatal disorder.

17 May 2017

Research findings could potentially improve early diagnosis of Alzheimer's disease

New research led by the University of Hertfordshire, may significantly change the understanding of cognitive processes that are most impaired at very early stages of Alzheimer’s disease.

17 May 2017

Scientists use AHDS patients’ cells to recreate disease and mimic blood-brain barrier

The blood-brain barrier is biology's proverbial double-edged sword. An impermeable shield of endothelial cells that protects our brains from toxins and other threats that may lurk in circulating blood, the barrier can also exclude therapeutic drugs and, at times, essential biomolecules required for healthy brain development.

17 May 2017

Researchers discover likely cause for visual impairment in Finnish variant of NCL

Researchers from the University of Eastern Finland have discovered a likely cause for visual impairment and eventual loss of vision in the Finnish variant of Neuronal Ceroid Lipofuscinosis.

17 May 2017

Weekly doses of steroids help hasten recovery in muscle injuries

Weekly doses of glucocorticoid steroids, such as prednisone, help speed recovery in muscle injuries, reports a new Northwestern Medicine study. The weekly steroids also repaired muscles damaged by muscular dystrophy.

17 May 2017

New research could be first step toward drug to treat Zika infections

New research led by Alexey Terskikh, Ph.D., associate professor at Sanford Burnham Prebys Medical Discovery Institute (SBP), and Alex Strongin, Ph.D., professor at SBP, could be a first step toward a drug to treat Zika infections. Publishing in Antiviral Research, the scientific team discovered a compound that prevents the virus from spreading.

16 May 2017

Scientists unravel mystery of T cell signaling process vital to immune response

The immune system cells known as T cells play a central role in the body's ability to fight infections and cancer. For decades, however, details of the molecular signaling process that leads to T cell activation have remained a mystery.

16 May 2017

EPFL scientists develop new antibody-linked biosensor to track drug concentration in the blood

Being able to monitor drug concentration in the blood of a patient is an important aspect of any pharmaceutical treatment. However, this requires equipment and facilities that are often missing from field healthcare in developing countries, but also inhibits the quality of life for patients elsewhere.

16 May 2017

Medical Science News

Microbes can manipulate molecular machinery of host cells to influence health

Researchers identify new drug target for two common types of myeloid leukemia

Researchers identify new way to prevent pneumococci from entering the brain

Researchers develop new strategy that can revolutionize HIV vaccine design

Scientists identify gene linked to incurable bowel disorders

Research identifies 'cell messages' that could help detect early stages of osteoarthritis

Study measures increased 'fight or flight' response in young veterans with combat-related PTSD

History of sleep: what was normal?

Researchers identify key inflammatory cells involved in nonalcoholic fatty liver disease

Small molecules in saliva show potential for early diagnosis of Alzheimer's disease

Children surviving chronic health conditions may suffer from brain function issues

‘Disease in a dish’ model pinpoints how defects in blood-brain barrier can cause psychomotor disorder

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

Research findings could potentially improve early diagnosis of Alzheimer's disease

Scientists use AHDS patients’ cells to recreate disease and mimic blood-brain barrier

Researchers discover likely cause for visual impairment in Finnish variant of NCL

Weekly doses of steroids help hasten recovery in muscle injuries

New research could be first step toward drug to treat Zika infections

Scientists unravel mystery of T cell signaling process vital to immune response

EPFL scientists develop new antibody-linked biosensor to track drug concentration in the blood

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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