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Potential mosquito-based malaria vaccine could be a step closer

A promising type of vaccine designed to eradicate malaria by blocking parasite transmission could be a step closer, as a result of experts uncovering new information about the targeted protein.

17 Jun 2015

Fruit flies helping FAU researchers to discover novel genes responsible for neuroprotection

They're pesky and annoying when they get into your fruit, but Drosophila melanogaster, more affectionately known as the "fruit fly," are helping researchers at Florida Atlantic University to discover novel genes that are responsible for neuroprotection.

17 Jun 2015

Experts review strategies that may help improve adoptive cell immunotherapy for treating cancer

In a special issue of Immunotherapy, leading experts provide in-depth review of innovative strategies that may further the success of adoptive cell immunotherapy as a cancer treatment. Adoptive cell immunotherapy (ACT) has proven successful in clinical trials against certain types of melanoma and leukemia. The journal reviews new strategies to address the challenges of extending these effects to a wider range of tumor types.

17 Jun 2015

Researchers assemble full genome of living organism using Oxford Nanopore's MinIONTM device

Researchers in Canada and the U.K. have for the first time sequenced and assembled de novo the full genome of a living organism, the bacteria Escherichia Coli, using Oxford Nanopore's MinIONTM device, a genome sequencer that can fit in the palm of your hand.

17 Jun 2015

CQDM, OCE grant $1.5M to speed up drug discovery and development in Quebec-Ontario Life Sciences Corridor

CQDM and Ontario Centres of Excellence will fund five highly innovative and unconventional game-changing research and development projects to accelerate drug discovery in the Quebec-Ontario Life Sciences Corridor. Partners are granting $1.5M to Quebec-based and, for the first time, Ontario-based researchers thanks to the partnership with OCE through CQDM's 2014 Explore Program, one of CQDM's flagship programs focusing on early concept validation of cutting-edge technologies that address the most crucial needs in drug discovery and development.

17 Jun 2015

Scientists identify two new key players involved in development of prostate cancer

Understanding how a normal healthy cell turns into a cancerous one is our best bet yet for beating the disease. It will help better diagnose the cancer type, and enable the development of more effective, and less toxic therapies. But cells have evolved all sorts of sophisticated ways to become cancerous, and identifying the molecules involved and how they function in each type of cancer is a major undertaking.

16 Jun 2015

Researchers locate promising target for potential vaccine against malaria

Researchers from the Johns Hopkins Bloomberg School of Public Health have located a new - and likely more promising, they say - target for a potential vaccine against malaria, a mosquito-borne illness that kills as many as 750,000 people each year.

16 Jun 2015

Lawson researchers find radiation-resistant stem cell population in the colon linked to cancer growth

Researchers at Lawson Health Research Institute have identified a new stem cell population in the colon linked to cancer growth. The findings, which were recently published in the prominent journal Cell Stem Cell, will significantly change the way we study and treat colon cancer.

16 Jun 2015

Key prostaglandin metabolic enzyme shows promise as drug target for tissue regeneration

A new study co-led by Hsin-Hsiung Tai, professor of pharmaceutical sciences at the University of Kentucky, suggests that a key prostaglandin (PG) metabolic enzyme shows promise as a drug target to help tissue regeneration and repair, particularly after bone marrow transplantation and tissue injuries.

16 Jun 2015

'Brain-to-Text' system decodes spoken speech and transforms it into textual representation

Speech is produced in the human cerebral cortex. Brain waves associated with speech processes can be directly recorded with electrodes located on the surface of the cortex. It has now been shown for the first time that is possible to reconstruct basic units, words, and complete sentences of continuous speech from these brain waves and to generate the corresponding text.

16 Jun 2015

Mutations in ZnT2 protein reduce amounts of zinc levels in mother's milk

Zinc plays an important role in a woman's ability to successfully breast-feed her child, according to health researchers.

16 Jun 2015

Researchers develop hPSC-based system for producing connections between neurons in the brain

Human stem cells can be differentiated to produce other cell types, such as organ cells, skin cells, or brain cells. While organ cells, for example, can function in isolation, brain cells require synapses, or connectors, between cells and between regions of the brain. In a new study published in Restorative Neurology and Neuroscience, researchers report successfully growing multiple brain structures and forming connections between them in vitro, in a single culture vessel, for the first time.

16 Jun 2015

TUSM researchers reveal how scratching evokes pleasurable sensation in chronic itch patients

It's long been known that scratching evokes a rewarding and pleasurable sensation in patients with chronic itch. Now, researchers in the Department of Dermatology and Temple Itch Center at Temple University School of Medicine may be closer to understanding why.

16 Jun 2015

Understanding crosstalk between cells in the pancreas can help treat diabetes

Sometimes, listening in on a conversation can tell you a lot. For Mark Huising, an assistant professor in the Department of Neurobiology, Physiology and Behavior at the UC Davis College of Biological Sciences, that crosstalk is between the cells that control your body's response to sugar, and understanding the conversation can help us understand, and perhaps ultimately treat, diabetes.

16 Jun 2015

Discovery could help scientists reduce global vitamin A deficiency

A research team's discovery of new information about how plants synthesize carotenoids, precursors for vitamin A that are essential for plant development and survival, and human health, could help scientists increase the levels of provitamin A in food crops and reduce global vitamin A deficiency.

16 Jun 2015

DAPK1 protein may be a promising new therapeutic target for most aggressive breast cancers

Although traditionally understood to induce death in cancer cells, researchers at The University of Texas MD Anderson Cancer Center have discovered that the DAPK1 protein is actually essential for growth in breast and other cancers with mutations in the TP53 gene. This discovery indicates DAPK1 may be a promising new therapeutic target for many of the most aggressive cancers.

16 Jun 2015

Vitamin D deficiency can leave people less able to fight HIV-1 infection

Vitamin D plays an important part in the human immune response and deficiency can leave individuals less able to fight infections like HIV-1. Now an international team of researchers has found that high-dose vitamin D supplementation can reverse the deficiency and also improve immune response.

16 Jun 2015

Study highlights discovery of genetic variants linked to mucinous ovarian carcinomas

New research by an international team including Keck Medicine of USC scientists is bringing the origins of ovarian cancer into sharper focus.

16 Jun 2015

Modifying small white blood cells may help treat immune disorders

Modifying the small white blood cells that protect against disease might help treat immune disorders, according to a study published in Cellular and Molecular Gastroenterology and Hepatology, the basic science journal of the American Gastroenterological Association.

16 Jun 2015

Researchers uncover new mechanism that innate immune system uses to curb viral infections

An innovative mechanism that the innate immune system uses to control viral infections has been uncovered by researchers at the University Medical Centers in Mainz and Freiburg. Central to this is the discovery that two different but related elements of the immune system can act together in concert to fight, for example, rotavirus infections.

16 Jun 2015

Medical Science News

Potential mosquito-based malaria vaccine could be a step closer

Fruit flies helping FAU researchers to discover novel genes responsible for neuroprotection

Experts review strategies that may help improve adoptive cell immunotherapy for treating cancer

Researchers assemble full genome of living organism using Oxford Nanopore's MinIONTM device

CQDM, OCE grant $1.5M to speed up drug discovery and development in Quebec-Ontario Life Sciences Corridor

Scientists identify two new key players involved in development of prostate cancer

Researchers locate promising target for potential vaccine against malaria

Lawson researchers find radiation-resistant stem cell population in the colon linked to cancer growth

Key prostaglandin metabolic enzyme shows promise as drug target for tissue regeneration

'Brain-to-Text' system decodes spoken speech and transforms it into textual representation

Mutations in ZnT2 protein reduce amounts of zinc levels in mother's milk

Researchers develop hPSC-based system for producing connections between neurons in the brain

TUSM researchers reveal how scratching evokes pleasurable sensation in chronic itch patients

Understanding crosstalk between cells in the pancreas can help treat diabetes

Discovery could help scientists reduce global vitamin A deficiency

DAPK1 protein may be a promising new therapeutic target for most aggressive breast cancers

Vitamin D deficiency can leave people less able to fight HIV-1 infection

Study highlights discovery of genetic variants linked to mucinous ovarian carcinomas

Modifying small white blood cells may help treat immune disorders

Researchers uncover new mechanism that innate immune system uses to curb viral infections

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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