Chromosome News and Research

Latest Chromosome News and Research

Mitochondrial dysfunction may be a contributor to schizophrenia

Researchers at Rutgers and Emory University are gaining insights into how schizophrenia develops by studying the strongest-known genetic risk factor.

16 Aug 2023

Next-generation sequencing provides novel insights into the mechanisms underlying autism and myotonic muscular dystrophy

The pathomechanistic connection between autism and myotonic muscular dystrophy type 1.

16 Aug 2023

Copy number profiling provides insight as to why prostate cancer may become lethal

Researchers performed genome-wide copy number profiling of the androgen receptor (AR) on metastases from deceased prostate cancer patients.

16 Aug 2023

Genetic determinants of retinol circulation and their impact on health

The genetic architecture of circulating retinol.

15 Aug 2023

UAB researchers identify cell-surface marker that indicates fate of T cells

Follicular helper T cells, or Tfh cells, have a crucial role in immune defense. Without Tfh cells, B cells cannot form germinal center, or GC, responses during which high-affinity antibodies are generated.

14 Aug 2023

New gene therapy shows promise for treating fusion-driven cancers

A new study presents a promising treatment method for so-called fusion-driven cancers, which are currently often difficult to cure. These fusion-driven cancers are caused by an error in cell division that creates a fusion of different genes.

11 Aug 2023

$11 million NIH grant focuses on cognitive function in Down syndrome-associated Alzheimer’s

Neurologist Beau Ances, MD, PhD, talks with his patient, Adam Kloppenberg, who has Down syndrome, at Washington University School of Medicine in St. Louis. People with Down syndrome are at very high risk of developing Alzheimer's disease. Ances is involved in a project led by Jason Hassenstab, PhD, an associate professor of neurology, to develop tools to measure cognitive function in people with Down syndrome-associated Alzheimer's disease.

3 Aug 2023

Genetic variant may explain why some people of African ancestry have lower HIV viral loads

An international team of researchers has found a genetic variant that may explain why some people of African ancestry have naturally lower viral loads of HIV, reducing their risk of transmitting the virus and slowing progress of their own illness.

2 Aug 2023

Study reveals two key mechanisms underlying high risks from lung infections in Down syndrome

Individuals with Down syndrome, the genetic condition caused by triplication of human chromosome 21, also known as trisomy 21, display a very high risk of hospitalization and mortality after developing lung infections.

2 Aug 2023

Phase 1 clinical trial underway to test City of Hope-developed cancer treatment

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, today published a new study explaining how they took a protein once thought to be too challenging for targeted therapy, proliferating cell nuclear antigen (PCNA), and developed a targeted chemotherapy that appears to annihilate all solid tumors in preclinical research.

1 Aug 2023

How do De novo sequencing, QTL mapping, WGS, and lcWGS empower breakthroughs in agrigenomics

Sequencing technology is playing an increasingly important role in agriculture, including crops, livestock and poultry, aquatic organisms, and more.

From MGI 27 Jul 2023

New refget version improves reliability of genomic data analysis

A widely-used tool that finds the exact references needed to pinpoint differences in our DNA just got a refresh.

19 Jul 2023

Study provides new insights into the mechanism of Dmc1 filament assembly

Homologous recombination (HR) is an important process that plays multiple crucial roles during meiosis, a type of cell cycle dedicated to sexual reproduction.

19 Jul 2023

Study reveals immune dysregulation in Down syndrome and potential therapeutic strategy

People with Down syndrome, the condition caused by an extra copy of chromosome 21, or trisomy 21, display chronic dysregulation of their immune system, which can contribute to high rates of autoimmune conditions and severe complications from respiratory infections.

17 Jul 2023

Overdosed gene on chromosome 21 accelerates aging in people with Down's syndrome

An overdosed gene on chromosome 21 causes people with Down's Syndrome to age faster than the general population.

12 Jul 2023

REDH database provides insights into RNA editing in hematopoietic cells

The process of converting DNA to proteins through an RNA is far from straightforward. Of the several types of RNA involved in the process of protein synthesis, a few may be edited mid-way.

10 Jul 2023

PacBio's Revio long-read sequencing system to help Bioscientia solve complex genetic cases

PacBio, a leading developer of high-quality, highly accurate sequencing solutions, today announced that Bioscientia is using its Revio long-read sequencing system to expand its genomics research projects and sequence several thousand human genomes per year.

10 Jul 2023

The Spectrum CE System: A capillary electrophoresis instrument for the forensic laboratory workflow

In this Interview, NewsMedical talks to Ben Krenke about the Spectrum CE system for Forensic laboratory workflow.

From Promega Corporation 7 Jul 2023

Aneuploidy could function as a therapeutic target for cancer

Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new Yale study reveals, and eliminating them prevents the cells from forming tumors.

6 Jul 2023

New therapy to mitigate fragile X syndrome may be on the horizon

An antisense therapy developed by Joel D. Richter, PhD, Sneha Shah, PhD, and Jonathan K. Watts, PhD, at UMass Chan Medical School and Elizabeth Berry-Kravis, MD, PhD, at RUSH University Medical Center, restores production of the protein FMRP in cell samples taken from patients with fragile X syndrome.

5 Jul 2023

Chromosome News and Research

Latest Chromosome News and Research

Mitochondrial dysfunction may be a contributor to schizophrenia

Next-generation sequencing provides novel insights into the mechanisms underlying autism and myotonic muscular dystrophy

Copy number profiling provides insight as to why prostate cancer may become lethal

Genetic determinants of retinol circulation and their impact on health

UAB researchers identify cell-surface marker that indicates fate of T cells

New gene therapy shows promise for treating fusion-driven cancers

$11 million NIH grant focuses on cognitive function in Down syndrome-associated Alzheimer’s

Genetic variant may explain why some people of African ancestry have lower HIV viral loads

Study reveals two key mechanisms underlying high risks from lung infections in Down syndrome

Phase 1 clinical trial underway to test City of Hope-developed cancer treatment

How do De novo sequencing, QTL mapping, WGS, and lcWGS empower breakthroughs in agrigenomics

New refget version improves reliability of genomic data analysis

Study provides new insights into the mechanism of Dmc1 filament assembly

Study reveals immune dysregulation in Down syndrome and potential therapeutic strategy

Overdosed gene on chromosome 21 accelerates aging in people with Down's syndrome

REDH database provides insights into RNA editing in hematopoietic cells

PacBio's Revio long-read sequencing system to help Bioscientia solve complex genetic cases

The Spectrum CE System: A capillary electrophoresis instrument for the forensic laboratory workflow

Aneuploidy could function as a therapeutic target for cancer

New therapy to mitigate fragile X syndrome may be on the horizon

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Chromosome News and Research

Latest Chromosome News and Research

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Newsletters you may be interested in