Collagen News and Research

Latest Collagen News and Research

Ice-templated fabrication shows promise for artificial bone

The next generation of artificial bone may rely on a few secrets from the sea. Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory have harnessed the way seawater freezes to develop a porous, scaffolding-like material that is four times stronger than material currently used in synthetic bone.

7 Feb 2006

Protein induces dental pulp stem cells into dentin-forming odontoblasts

When dentists examine patients with a damaged tooth that has become infected and abscessed, or filled with tissue-eroding fluid, they typically have two options: Root canal or extraction.

15 Dec 2005

Generation of neoantigenic epitopes after posttranslational modification of Type II collagen by factors present within the inflamed joint

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints, which gradually erodes the cartilage and bone.

7 Dec 2005

New study sheds light on role of type II collagen in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease which gradually erodes cartilage and bone and is characterised by chronic inflammation of the joints.

6 Dec 2005

Alagebrium may prevent arterial aging in patients with systolic hypertension

A compound called alagebrium, which is very similar to another used in anti-wrinkle creams, may be useful in reducing the deleterious effects of arterial aging in the majority of elderly Americans with systolic hypertension, a new study from researchers at Johns Hopkins shows.

5 Dec 2005

Researchers move in on novel therapeutics to inhibit melanoma

Northwestern University researchers have developed a novel, three-dimensional model that allows scientists to observe how interacting with the microenvironment of metastatic melanoma cells induces normal skin cells to become similar to aggressive cancer cells that migrate and spread throughout the body.

5 Dec 2005

Stem cell microenvironment reverses malignant melanoma

Northwestern University researchers have demonstrated how the microenvironments of two human embryonic stem cell (hESC) lines (federally approved) induced metastatic melanoma cells to revert to a normal, skin cell-like type with the ability to form colonies similar to hESCs.

20 Nov 2005

Scientists direct embryonic stem cells to become cartilage cells

Scientists from Imperial College London have successfully converted human embryonic stem cells into cartilage cells, offering encouragement that replacement cartilage could one day be grown for transplantation.

20 Nov 2005

Biologically engineered blood vessels now an option in cardiac bypass

The first-ever human use of completely biologically engineered blood vessels grown from a person's own cells could be an option for people who have vessels too damaged for heart bypass, researchers reported at the American Heart Association's Scientific Sessions 2005.

16 Nov 2005

Scientists use stem cells to grow cartilage

16 Nov 2005

World first trial grows blood vessels from patient's own skin

A team of American scientists have successfully implanted blood vessels grown entirely from a patient's own cells.

16 Nov 2005

Paclitaxel may help treat scleroderma

Using a novel model for scleroderma, researchers from Duke University Medical Center have discovered two important insights into this devastating disorder - the anti-cancer drug paclitaxel (Taxol) may prevent the skin thickening and small blood vessel destruction that characterizes the disease.

1 Nov 2005

New technique reveals the strength of bones

Scientists have developed a technique which can be used to reveal the strength of bones, allowing doctors to more accurately estimate the risk of bone fracture.

25 Oct 2005

20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis

A new study from the University of North Carolina at Chapel Hill School of Medicine may have found a way to identify those at greatest risk, thereby allowing doctors to decide who should receive treatment that could save the transplanted organ. The new findings appear in the October issue of the journal Liver Transplantation.

9 Oct 2005

Potential biomarker that could be used to predict who might develop hepatic fibrosis

Two new studies on Hepatitis C (HCV) patients who underwent liver transplants examined a potential biomarker that could be used to predict who might develop hepatic fibrosis, a formation of scar-like tissue that can lead to cirrhosis.

3 Oct 2005

Fever of unknown origin might be a marker of occult cancer

Fever of unknown origin is characterised by a fever of more than 3 weeks’ duration, temperatures of more than 38.3°C and a failure to identify the origin of the fever. Underlying causes of these fevers are difficult to diagnose, but proposed causes are infections, cancers and collagen-vascular diseases.

28 Sep 2005

The immune mechanisms of atherosclerosis

Scientists are depicting a novel scheme for atherosclerosis development, suggesting that this pathology might result from an imbalance between pro-inflammatory processes and calming ones.

28 Sep 2005

Two proteins for the diagnosis of lung diseases

Lung function pathology takes in some 200 diseases which have much radiological and pathological data in common, and which can greatly shorten the life of the patient, the last resort being a lung transplant.

1 Sep 2005

Simple new way to modify collagen, paving the way for better infection-fighting bandages

Collagen often pops up in beauty products and supermodel lips. But by mating collagen with a molecular hitchhiker, materials scientists at Johns Hopkins hope to create some important medical advances.

30 Aug 2005

Disease modifying activity of 2ME2 demonstrated in preclinical rheumatoid arthritis studies

EntreMed a clinical-stage pharmaceutical company developing therapeutics primarily for the treatment of cancer and inflammatory diseases, has announced the presentation of positive preclinical results for its lead compound, 2-methoxyestradiol (2ME2), in models of rheumatoid arthritis.

24 Aug 2005