Embryogenesis News and Research

Latest Embryogenesis News and Research

Penn researchers track defective sperm epigenome linked to male infertility

One out of eight couples has trouble conceiving, with nearly a quarter of those cases caused by unexplained male infertility. For the past decade, research has linked that infertility to defective sperm that fail to "evict" proteins called histones from DNA during development.

16 Dec 2019

Important discovery about male infertility could lead to new treatments

Using a new mouse model, Penn Medicine researchers have identified defects in the sperm epigenome that cause male infertility.

16 Dec 2019

International project to preserve genetic resources of birds

The support is provided by the Russian Foundation for Basic Research and the Science and Innovation in East Asia Consortium. Kazan Federal University's partners are Mahidol University and Kumamoto University.

14 Dec 2019

A large library of products derived from fungi could help find new drugs

An enormous library of products derived from more than ten thousand fungi could help us find new drugs.

26 Nov 2019

Study shows how cell competition corrects noisy morphogen gradients during embryogenesis

Tissue patterning is an important process during embryo formation, as well in adult tissue, which ensures that groups of cells are correctly arranged to allow them to function properly.

23 Oct 2019

Findings shed light on molecular reasons for early miscarriage

Researchers at Karolinska Institutet in Sweden have uncovered a chromosome-wide mechanism that keeps the gene expression of sex chromosomes in balance in our cells.

3 Oct 2019

Researchers shed new light on how the brain constructs itself

The cerebral cortex acts as the control center of our cognitive processes. During embryogenesis, dozens of types of neurons with distinct functions come together to form the circuits that drive our thoughts and actions.

29 Aug 2019

Biologists discover the intricacies of 'on/off switch' that creates cell differentiation

A team of biologists has discovered how cells become different from each other during embryogenesis, a finding that offers new insights into genetic activity and has implications for better understanding the onset of disease and birth defects.

12 Aug 2019

Novel agent shown to have dual mechanism of action to eliminate cancer

Results from a study spearhead by researchers at the Vall d´Hebron Institute of Oncology (VHIO), show that the blockade of the multi-functional cytokine LIF induces tumor-infiltrating T Cells to hone in on and eliminate cancer.

11 Jun 2019

Spatial configuration of the genome is not inherited, but set up during embryogenesis

The architecture of the DNA-protein complexes that make up the genome in each cell nucleus regulates the course of early embryonic development.

23 May 2019

KZFPs play a key role in the regulation of human genome

The human genome is fascinating. Once predicted to contain about a hundred thousand protein-coding genes, it now seems that the number is closer to twenty thousand, and maybe less.

19 Apr 2019

Single lineage of stem cells contributes to lifelong hippocampal neurogenesis in mice

Scientists once thought that mammals entered adulthood with all of the neurons they would ever have, but studies from the 60s found that new neurons are generated in certain parts of the adult brain and pioneering studies from the 90s helped identify their origins and function.

29 Mar 2019

Researchers elucidate how embryonic cells and tissues respond to force

Accumulated evidence suggests that physical force plays an important role in various developmental processes of fertilized animal eggs.

8 Mar 2019

Salk team uses new model to study health effects of AMP-activated protein kinase

The metabolic protein AMPK has been described as a kind of magic bullet for health. Studies in animal models have shown that compounds that activate the protein have health-promoting effects to reverse diabetes, improve cardiovascular health, treat mitochondrial disease--even extend life span.

16 Jan 2019

Researchers identify multisystem disorder caused by bi-allelic variants in CCDC47 gene

Researchers and clinicians through a multicenter collaboration have identified a novel multisystem disorder caused by bi-allelic variants in the CCDC47 gene. Their findings are reported in the American Journal of Human Genetics.

20 Nov 2018

Researchers investigate why some cancers affect only young women

Among several forms of pancreatic cancer, one of them affects specifically women, often young. How is this possible, even though the pancreas is an organ with little exposure to sex hormones? This pancreatic cancer, known as "mucinous cyst", has strange similarities with another mucinous cancer, affecting the ovaries.

19 Oct 2018