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Salt water treatment for cystic fibrosis both effective and cheap

Published on January 19, 2006 at 4:59 PM · No Comments

Two teams of scientists working half a world apart, have identified what they believe is a simple, effective and inexpensive treatment to reduce lung problems associated with cystic fibrosis.

Cystic fibrosis is the leading fatal genetic illness among whites, and victims suffer from a mucus build-up in the lungs that makes breathing difficult.

Cystic fibrosis appears on average in one of four children of parents who both carry a defective copy of a gene known as CFTR.

Children born with the disease soon develop chronic lung damage, since their lungs cannot clear the excessively sticky mucus by sweeping it to the mouth, where it is swallowed and eliminated.

Respiratory failure is the leading cause of death in CF patients.

The scientists say that salt water can ease the condition, and by inhaling a saltwater aerosol solution for between 10 and 15 minutes at least twice a day, young patients should be able to avoid a significant part of the damage the disease causes to their lungs.

The new therapy also appears to be safe and easy to take.

According to the researchers the aerosolized saltwater restores the thin lubricant layer of water that normally coats airway surfaces.

Apparently the water layer promotes the clearance of the naturally occurring mucus the body uses to trap harmful bacteria, viruses and other foreign particles.

The teams from the University of North Carolina at Chapel Hill School of Medicine and UNC Hospitals, worked with the Royal Prince Alfred Hospital, the University of Sydney and the Woolcock Institute of Medical Research, all in Sydney.

The scientists say they are excited that such a simple and inexpensive therapy appears to be so effective and well-tolerated in patients with CF.

They are optimistic that the therapy will reduce how often patients are ill, and will slow the decline of lung function over time and extend their life span.

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