Peyronie's disease (PD) is a localized connective tissue disorder that primarily affects the tunica albuginea and the areolar space between the tunica albuginea and erectile tissue.
The majority of men with PD retain the ability to obtain and maintain an erection. However, they may have difficulties in achieving vaginal penetration and sexual activity, as a result of curvature, pain on intromission or partner dyspareunia. Inadequate erections are reported in about 20% of patients with symptomatic PD.
A recent review by Ahmed El-Sakka from Makkah, Saudi Arabia, examined the prevalence of Peyronie’s disease among a population of men complaining of erectile dysfunction. Also analyzed were the risk factors and medical comorbidities in patients with this disease. The review is published in the March, 2006 issue of European Urology.
A prospective office-based study was performed from December 2001 to December 2004 and 1,440 male patients with a clinical diagnosis of ED were enrolled in the study. Patients were interviewed for ED using the IIEF. Patients were also interviewed for socio-demographic factors and relevant medical history. Socio-demographic factors included age, obesity and smoking habits. Medical history and risk factors included diabetes, hypertension, dyslipidemia, and psychological disorders. The diagnosis of Peyronie’s disease was based on a penile plaque on routine examination of the penis, or acquired penile curvature that was confirmed by using an intracorporeal injection of 10mcg of prostaglandin E1.