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Causes of male infertility

Published on October 18, 2007 at 11:25 AM · No Comments

Two reports from physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center shed new light on male infertility.

A first report shows that a common cause of male infertility -- varicoceles, or varicose veins in the scrotum -- also results in a depletion of testosterone. In a second related finding, researchers demonstrate that once a common, simple surgery is used to treat varicoceles and thereby restore fertility, testosterone levels are also improved.

Dr. Marc Goldstein, Professor of Urology and Reproductive Medicine at Weill Cornell Medical College and attending urologist at NewYork-Presbyterian/Weill Cornell, has presented his novel research at the 2007 annual meeting of the American Society for Reproductive Medicine (ASRM) in Washington, D.C.

"People often forget or often don't realize that the testes have two purposes," says Dr. Goldstein, who was also awarded the prestigious Howard and Georgeanna Jones Life Time Achievement Award by the American Fertility Association. "One is the production of the sex cells (sperm), and the other is to produce testosterone."

In his research, Dr. Goldstein hypothesized, and later found that, the presence of varicoceles causes significantly lower testosterone levels. He also observed that following varicocele removal, testosterone levels are greatly improved -- up to 100 percent -- in more than two-thirds of the men studied.

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