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New imaging technology lights up lungs to diagnose disease

Published on April 28, 2008 at 8:12 PM · No Comments

Researchers at the University of Sheffield have developed innovative technology which illuminates a person's lungs and helps clinicians identify if they are functioning correctly. The new technology could result in earlier diagnosis of emphysema and smoking related damage, as well as other lung conditions and diseases.

Lung diseases are of growing concern to the health of the nation, with people suffering from conditions as mild as asthma or as severe as lung cancer. By detecting lung damage early, doctors could help slow down or stop the conditions.

The technique developed at Sheffield involves a person inhaling small amounts of harmless hyperpolarised (HP) noble gases (Helium-3 and Xenon-129), which are then imaged inside an MRI scanner. The gases are hyperpolarised using high power lasers by a process called optical pumping. The high resolution images of the airspaces that are produced offer additional functional information that is currently not available with traditional X-rays and lung CT scans.

The first clinical studies using this novel method have been carried out at the University of Sheffield, with the University holding the only UK regulatory licence to administer hyperpolarised gases for lung imaging.

Images obtained of lungs so far are shedding new light on a variety of different lung conditions and diseases. Tests carried out on smokers, for example, have shown signs of early emphysema.

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