Malvern Panalytical will showcase the new Morphologi G3-ID particle characterization system at Drug Delivery to the Lungs 23, which takes place from 5 – 7 Dec 2012 in Edinburgh, Scotland. The company will highlight the system’s ability to generate component-specific particle size and shape data that efficiently support the commercialization of both new and generic Orally Inhaled and Nasal Dry Products (OINDPs). Activities at the conference will include a poster presentation that details results from a new study in which the Morphologi G3-ID was used to successfully measure nasal sprays in the formulated liquid state with minimal sample preparation.
The Morphologi G3-ID combines imaging technology with Raman spectroscopy to generate size, shape and chemical identification data from a single platform. In OINDP characterization it complements Malvern Panalytical’s laser diffraction instruments for rapid particle size measurement – the Mastersizer 3000 and Spraytec – and indeed other techniques such as cascade impaction, by reliably differentiating even morphologically identical particles to generate data for specific formulation components. The Morphologi G3-ID therefore presents an efficient solution for applications such as: foreign contaminant detection; verification of active ingredient particle size pre- and post- delivery for nasal suspensions (in line with regulatory guidance); and detailed investigation of the delivered particle size of dry powder inhaler actives.
The Malvern Panalytical poster presentation for DDL 23 is ‘Measuring the particle size of the active components of nasal sprays in the formulated liquid state’. It details a methodology for wet measurement that extends efficient application of the Morphologi G3-ID beyond dry powder characterization. Company experts will be on hand throughout the conference to discuss the work and more generally how Malvern Panalytical’s analytical instruments work in tandem to support the evolution of OINDP technology.
Malvern Panalytical, Malvern Panalytical and Morphologi are registered trademarks of Malvern Panalytical
Spraytec is a trademark of Malvern Panalytical
About Malvern Panalytical
Malvern Panalytical is a market leader in measuring performance controlling material properties. These include particle size, particle shape, zeta potential, molecular weight, size and conformation, rheological properties and chemical identification. Malvern Panalytical delivers the systems, support and expertise that ensure the analytical integrity and productivity needed to drive research, development and manufacturing.
Malvern Panalytical’s measurement solutions for scientists, technologists and engineers advance continually through customer collaboration. Complementary materials characterization systems deliver inter-related measurements that reflect the complexities of particulates and disperse systems, nanomaterials and macromolecules. Combining intelligently implemented technologies with in-depth industry applications knowledge and support, Malvern Panalytical provides customers with the competitive advantage they demand.
Headquartered in Malvern Panalytical, UK, Malvern Panalytical has subsidiary organizations in all major European markets, North America, China, Japan and Korea, a joint venture in India, a global distributor network and applications laboratories around the world. www.malvern.com
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