Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Ceregene announces top-line data from CERE-12 Phase 2b clinical study for Parkinson's disease

Ceregene, Inc. today announced the top-line data from its double-blind, randomized, controlled Phase 2b clinical study of CERE-120 (AAV-neurturin), a gene therapy product designed to deliver the neurotrophic factor neurturin, for Parkinson's disease.

20 Apr 2013

NIH-funded study to develop measure of quality of life specific to caregivers of persons with TBI

Kessler Foundation is one four sites participating in "Quality of Life in Caregivers of Traumatic Brain Injury: The Development of the TBI-CareQOL", a multi-site 5-year study funded by the National Institutes of Health/National Institute of Nursing Research (1R01NR013658-01).

20 Apr 2013

Civitas Therapeutics reports positive results from Phase 2 study of CVT-301 for Parkinson's disease

Civitas Therapeutics, Inc., a privately-held pharmaceutical company developing transformative therapeutics using the ARCUS respiratory delivery platform, today announced positive topline results from a Phase 2 clinical trial of CVT-301, an inhaled formulation of levodopa (L-dopa).

20 Apr 2013

Research findings describe specific profile of patients with ACLF

In this prospective study, led by Dr Richard Moreau, INSERM Research Director (Mixed Research Unit 773 "Centre de Recherche biom-dicale Bichat-Beaujon"; INSERM/Universit- Paris Diderot) who is also a practitioner attached to the Hepatology Department of the Beaujon Hospital (AP-HP), researchers studied a cohort of 1343 patients from 12 European countries.

20 Apr 2013

Researchers map use of alternative treatment among multiple sclerosis patients

A major Nordic research project involving researchers from the University of Copenhagen has, for the first time ever, mapped the use of alternative treatment among multiple sclerosis patients - knowledge which is important for patients with chronic disease and the way in which society meets them.

19 Apr 2013

Research shows respiratory syncytial virus can be transferred during pregnancy to unborn baby

The most common cause of lower respiratory tract infections in infants and young children, respiratory syncytial virus (RSV), can be transferred during pregnancy to an unborn baby, according to Cleveland Clinic Children's Hospital research published online this week in the journal PLOS ONE.

19 Apr 2013

Three MGH projects named among Top 10 Clinical Research Achievements of 2012

Three projects led by Massachusetts General Hospital investigators have been named among the Clinical Research Forum's Top 10 Clinical Research Achievements of 2012.

19 Apr 2013

New study shows reduction of dementia risk

A new Swedish study published in the journal Neurology shows that the risk of developing dementia may have declined over the past 20 years, in direct contrast to what many previously assumed.

19 Apr 2013

Abnormal protein translation leads to Fragile X ataxia, study finds

A bizarre twist on the usual way proteins are made may explain mysterious symptoms in the grandparents of some children with mental disabilities.

19 Apr 2013

Content of exosomes mirrors aggressiveness of brain tumour, study shows

"Current wisdom says that cells are closed entities that communicate through the secretion of soluble signalling molecules. Recent findings indicate that cells can exchange more complex information - whole packages of genetic material and signalling proteins.

19 Apr 2013

Newly redesigned Flexitron brachytherapy afterloading platform to be introduced at ABS meeting

At the 2013 American Brachytherapy Society meeting April 18-20 in New Orleans, Nucletron, an Elekta company, (booth #300), will introduce its newly redesigned Flexitron remote afterloading platform.

From Elekta 19 Apr 2013

GBM brain cancer patient treated with DCVax-L celebrates 10th anniversary of cancer-free survival

Northwest Biotherapeutics, a biotechnology company developing DCVax personalized immune therapies for solid tumor cancers, announced today that Brad Silver, an All American swimming and water polo athlete who was diagnosed with Glioblastoma multiforme brain cancer in late 2002, and was treated with DCVax-L in March of 2003, just celebrated the 10th anniversary of his continued cancer-free survival.

19 Apr 2013

FDA agrees to allow ADial to move forward with Phase III trial of AD04 for alcohol use disorder

ADial Pharmaceuticals, LLC, announced today that the U.S. Food and Drug Administration has agreed to allow ADial to move forward with its plan to initiate Phase III trials of AD04 as a treatment for alcohol use disorder in certain targeted genotypes population only.

19 Apr 2013

Research shows infants experience automatic calming reaction when carried by their mothers

There is a very good reason mothers often carry their crying babies, pacing the floor, to help them calm down. New research published in the Cell Press journal Current Biology on April 18 shows that infants experience an automatic calming reaction upon being carried, whether they are mouse or human babies.

19 Apr 2013

Excess glutamate drives schizophrenia in high-risk individuals

An excess of the brain neurotransmitter glutamate may cause a transition to psychosis in people who are at risk for schizophrenia, reports a study from investigators at Columbia University Medical Center published in the current issue of Neuron.

19 Apr 2013

Family members of trauma patients can benefit by being present during critical moments of care

A critically injured person is wheeled into the emergency room. Family members rush to the patient's side. Soon, doctors and nurses begin emergency resuscitation efforts, inserting breathing tubes, pumping in blood and other fluids.

19 Apr 2013

Researcher explores new way to deliver therapy to brain metastases from primary breast cancer

An Indiana University School of Medicine breast cancer surgeon is pursuing research that will utilize glass, gold, nanotechnology and Greek mythology hoping to vanquish breast cancer that has metastasized to the brain.

19 Apr 2013

Longer looks: The timely trauma response in Boston; Problems with aging doctors; Transplants from donors with HIV

The bombs at the Boston Marathon were designed to maim and kill, and they did. Three people died within the first moments of the blast. More than a hundred and seventy people were injured. They had their limbs blown off, vital arteries severed, bones fractured, flesh torn open by shrapnel or scorched by the blasts' heat. Yet it now appears that every one of the wounded alive when rescuers reached them will survive.

19 Apr 2013

Elevated responsivity of reward regions in the brain increases risk for future substance use

Do people get caught in the cycle of overeating and drug addiction because their brain reward centers are over-active causing them to experience greater cravings for food or drugs? In a unique prospective study Oregon Research Institute senior scientist Eric Stice, Ph.D., and colleagues tested this theory, called the reward surfeit model.

19 Apr 2013

Study highlights how genes can acquire, adapt to different roles in human evolution

Researchers have designed a method that can universally test for evolutionary adaption, or positive (Darwinian) selection, in any chosen set of genes, using re-sequencing data such as that generated by the 1000 Genomes Project.

19 Apr 2013

Brain News and Research

Further Reading

Ceregene announces top-line data from CERE-12 Phase 2b clinical study for Parkinson's disease

NIH-funded study to develop measure of quality of life specific to caregivers of persons with TBI

Civitas Therapeutics reports positive results from Phase 2 study of CVT-301 for Parkinson's disease

Research findings describe specific profile of patients with ACLF

Researchers map use of alternative treatment among multiple sclerosis patients

Research shows respiratory syncytial virus can be transferred during pregnancy to unborn baby

Three MGH projects named among Top 10 Clinical Research Achievements of 2012

New study shows reduction of dementia risk

Abnormal protein translation leads to Fragile X ataxia, study finds

Content of exosomes mirrors aggressiveness of brain tumour, study shows

Newly redesigned Flexitron brachytherapy afterloading platform to be introduced at ABS meeting

GBM brain cancer patient treated with DCVax-L celebrates 10th anniversary of cancer-free survival

FDA agrees to allow ADial to move forward with Phase III trial of AD04 for alcohol use disorder

Research shows infants experience automatic calming reaction when carried by their mothers

Excess glutamate drives schizophrenia in high-risk individuals

Family members of trauma patients can benefit by being present during critical moments of care

Researcher explores new way to deliver therapy to brain metastases from primary breast cancer

Longer looks: The timely trauma response in Boston; Problems with aging doctors; Transplants from donors with HIV

Elevated responsivity of reward regions in the brain increases risk for future substance use

Study highlights how genes can acquire, adapt to different roles in human evolution

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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