Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Medi-551 antibody treatment decreases number of cancer stem cells by half in multiple myeloma patients

An experimental antibody treatment decreased by half the number of cancer stem cells that drive the growth of tumors in nearly all patients with multiple myeloma, a cancer of the bone marrow and bone tissue, according to results of a preliminary clinical trial led by Johns Hopkins Kimmel Cancer Center scientists.

18 Apr 2016

First-ever nivolumab drug trial for rare, malignant SCCA shows positive results

A rare malignancy known as squamous cell carcinoma of the anal canal (SCCA) is on the increase, and now researchers have reported results of the first-ever phase II clinical trial results for treatment with the immunotherapy drug nivolumab.

18 Apr 2016

Johns Hopkins study suggests updated universal screening for hepatitis C virus

A review of blood samples for nearly 5,000 patients seen at The Johns Hopkins Hospital Emergency Department suggests that federal guidelines for hepatitis C virus (HCV) screening may be missing up to a quarter of all cases and argues for updated universal screening.

15 Apr 2016

Binding Site to collarborate in iStopMM (Iceland Screens, Treats or Prevents Multiple Myeloma) trial

Binding Site is proud to be a key collaborator with Prof Sigurdur Kristinsson of the University of Iceland in his pivotal MGUS screening study for the forthcoming iStopMM (Iceland Screens, Treats or Prevents Multiple Myeloma) trial.

From Binding Site 14 Apr 2016

Tackling superbugs with antibiotic resistance breakers: an interview with Professor Colin Garner, Chief Executive, Antibiotic Research UK

Superbugs – or to give them their correct name, antibiotic resistant bacteria – arise on repeated exposure to antibiotics. In any population of bacteria there will be a few that are antibiotic resistant (approximately 1 in 100 million bacteria). If these bacteria are allowed to grow and multiply, an antibiotic resistant infection results.

13 Apr 2016

International scientists discuss new treatments for non small cell lung cancer

More than 30 prominent international scientists gathered to discuss the state-of-the-art, as well as promising future approaches for the treatment of lung cancer at the stunning 17th century Borgo San Luigi, in Monteriggion, in the heart of the Tuscany countryside.

13 Apr 2016

Manipulation of signals in nervous system can enhance recovery after traumatic injury

Neurobiologists at UC San Diego have discovered how signals that orchestrate the construction of the nervous system also influence recovery after traumatic injury. They also found that manipulating these signals can enhance the return of function.

12 Apr 2016

Cell-signaling protein holds key to understanding autoantibody formation in lupus patients

A signaling molecule called interferon gamma could hold the key to understanding how harmful autoantibodies form in lupus patients. The finding could lead to new treatments for the chronic autoimmune disease, said researchers at Penn State College of Medicine.

12 Apr 2016

PATH and SD/Alere announce commercial availability of two diagnostic tools for NTDs

PATH and Standard Diagnostics/Alere announced today the commercial availability of two rapid diagnostic tools for onchocerciasis and lymphatic filariasis. Designed for use in disease surveillance, the antibody-based tests are part of a suite of diagnostic innovations intended to support the elimination of neglected tropical diseases (NTDs), a group of illnesses that affect more than a billion people worldwide.

12 Apr 2016

New biomarker discovery could improve chances of developing effective TB vaccine

A team of scientists led by Oxford University have made a discovery that could improve our chances of developing an effective vaccine against Tuberculosis.

12 Apr 2016

Cornell researchers discover potential way to penetrate blood brain barrier

Cornell researchers have discovered a way to penetrate the blood brain barrier (BBB) that may soon permit delivery of drugs directly into the brain to treat disorders such as Alzheimer's disease and chemotherapy-resistant cancers.

11 Apr 2016

Innovative HIV vaccine candidate generates protection against repeated AIDS virus exposures

Mymetics Corporation, a pioneer in the research and development of virosome-based vaccines to prevent transmission of human infectious diseases across mucosal membranes, announced today that its innovative HIV vaccine candidate has shown to generate significant protection in groups of twelve female monkeys against repeated AIDS virus exposures during part of the preclinical study.

11 Apr 2016

HPV vaccination may be beneficial for CKD patients but not for kidney transplant recipients

Human papillomavirus (HPV) vaccination stimulates robust and sustained immune responses in girls and young women with chronic kidney disease (CKD) and those on dialysis, but less optimal responses to the vaccine were observed among those with a kidney transplant.

11 Apr 2016

Rituximab shows second-line promise in autoimmune limbic encephalitis

Rituximab is an effective and well-tolerated second-line treatment for patients with autoimmune limbic encephalitis, suggests research.

7 Apr 2016

Genetically modified pig hearts can survive for more than 2 years after transplantation into baboons

Could organs explanted from other mammals save human lives someday? A new study shows that genetically modified pig hearts developed by US and Ludwig-Maximilians-Universitaet in Munich researchers can survive for more than up to 2½ years when transplanted into baboons.

7 Apr 2016

Ludwig, CRI launch Phase 1/2 trial of combination immunotherapy for advanced ovarian cancer

Ludwig Cancer Research and the Cancer Research Institute have launched a Phase 1/2 clinical trial of combination immunotherapy for advanced ovarian cancer. The international, multicenter trial is led by George Coukos, director of the Ludwig Institute for Cancer Research, Lausanne and Brad Monk, director of Gynecologic Oncology at St. Joseph's Hospital and Medical Center.

7 Apr 2016

New immune-suppressing therapy leads to longer survival for cross-species heart transplant

A new immune-suppressing therapy has led to the longest survival yet for a cross-species heart transplant, according to new research conducted in part by researchers at the University of Maryland School of Medicine.

7 Apr 2016

Structure-based approach could lead to effective HIV vaccine

It's been known for some time that the immune system can produce antibodies capable of "neutralizing" HIV, and stopping the AIDS-causing virus dead in its tracks.

7 Apr 2016

SCIEX and QPS Holdings enter collaboration to establish the BioBA solution for bioanalysis of biologics

SCIEX, a global leader in life science analytical technologies, and QPS Holdings, LLC (QPS), a leading global full-service Contract Research Organization (CRO), today announced a collaboration to advance Hybrid LBA –LCMS, a workflow for routine biologics quantification. Under the agreement, QPS Holdings will deploy the SCIEX BioBA Solution, the first end-to-end and most complete solution for bioanalysis of biologics.

6 Apr 2016

First-ever immature antibody found in immune molecules may help combat HIV

Scientists at The Scripps Research Institute and collaborating institutions have described the first-ever immature or “teenage” antibody found in a powerful class of immune molecules effective against HIV.

6 Apr 2016

Antibody News and Research

Further Reading

Medi-551 antibody treatment decreases number of cancer stem cells by half in multiple myeloma patients

First-ever nivolumab drug trial for rare, malignant SCCA shows positive results

Johns Hopkins study suggests updated universal screening for hepatitis C virus

Binding Site to collarborate in iStopMM (Iceland Screens, Treats or Prevents Multiple Myeloma) trial

Tackling superbugs with antibiotic resistance breakers: an interview with Professor Colin Garner, Chief Executive, Antibiotic Research UK

International scientists discuss new treatments for non small cell lung cancer

Manipulation of signals in nervous system can enhance recovery after traumatic injury

Cell-signaling protein holds key to understanding autoantibody formation in lupus patients

PATH and SD/Alere announce commercial availability of two diagnostic tools for NTDs

New biomarker discovery could improve chances of developing effective TB vaccine

Cornell researchers discover potential way to penetrate blood brain barrier

Innovative HIV vaccine candidate generates protection against repeated AIDS virus exposures

HPV vaccination may be beneficial for CKD patients but not for kidney transplant recipients

Rituximab shows second-line promise in autoimmune limbic encephalitis

Genetically modified pig hearts can survive for more than 2 years after transplantation into baboons

Ludwig, CRI launch Phase 1/2 trial of combination immunotherapy for advanced ovarian cancer

New immune-suppressing therapy leads to longer survival for cross-species heart transplant

Structure-based approach could lead to effective HIV vaccine

SCIEX and QPS Holdings enter collaboration to establish the BioBA solution for bioanalysis of biologics

First-ever immature antibody found in immune molecules may help combat HIV

Antibodies eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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