Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Brown fat in humans: more than previously thought

Brown fat is a tissue well studied in small mammals, where it acts as a heat-producing organ to stay warm in a cold environment. Its unequivocal identification in adult, healthy humans about a decade ago is of major importance due to its immense capacity to convert chemical energy into heat

20 Apr 2017

Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeutics

Cocaine, nicotine, capsaicin. These are just three familiar examples of the hundreds of thousands of small molecules (also called specialized or secondary metabolites) that plants use as chemical ammunition to protect themselves from predation.

17 Apr 2017

Study may provide insight into how R-LA promotes death of hepatoma cells

A new study that measured metabolite levels over time in starved rat liver cancer cells showed that treatment with a form of alpha-lipoic acid (LA) inhibited glucose uptake and glycolysis, and led to decreased cellular glucose production from non-carbohydrate sources, which may help explain how the naturally occurring R enantiomeric form of LA (R-LA) promotes the death of hepatoma cells.

12 Apr 2017

Metabolite produced by intestinal bacteria protects against type 2 diabetes, study shows

A high concentration of indolepropionic acid in the serum protects against type 2 diabetes, shows a new study from the University of Eastern Finland. Indolepropionic acid is a metabolite produced by intestinal bacteria, and its production is boosted by a fibre-rich diet.

11 Apr 2017

Gene CRY1 variant alters circadian clock contributing to delayed sleep phase disorder, study finds

If all your life, you have been functioning best in the evening and night compared to the mornings, a gene mutation may be a reason.

10 Apr 2017

Children's hands may carry significant levels of nicotine, study shows

Children may carry significant levels of nicotine on their hands just by coming into contact with items or surfaces contaminated with tobacco smoke residues, even when no one is actively smoking around them at the time.

6 Apr 2017

Unique metabolic ‘signature’ in urine may help predict development of diabetes in obese teenagers

Researchers have discovered a unique metabolic "signature" in the urine of diabetic, obese black teenagers that they say may become a way to predict the development of type 2 diabetes in people at risk.

4 Apr 2017

Pyrethroid pesticide exposure may cause earlier sexual maturity in boys

Environmental exposure to common pesticides may cause boys to reach sexual maturity earlier, researchers have found. They will present their study results Saturday at the Endocrine Society's 99th annual meeting in Orlando, Fla.

2 Apr 2017

Researchers identify appetite-suppression mechanism in flies

Researchers have identified a molecule sent by fat cells to the fly brain that senses when they have had enough food and inhibits feeding, according to a study publishing March 28 in the open access journal PLOS Biology by Walton Jones of the Korea Advanced Institute of Science and Technology in Daejeon, and colleagues.

29 Mar 2017

Platforms for NMR software for spectrometer control and data analysis announced by Bruker

New Magnetic Resonance Technologies and Applications Open New Frontiers for Biological, Chemical and Materials Research and Routine Analysis in Pharmaceutical and Chemical Industries.

28 Mar 2017

Sphere Medical introduces new functionality to Proxima platform for efficient critical care patient monitoring

Sphere Medical, an innovative company in critical care monitoring and diagnostics equipment, announces the introduction of new functionality to its Proxima™ bedside blood gas, electrolyte and metabolite analyser.

22 Mar 2017

Bruker Nano Surfaces to hold webinar on label-free FLIM-based metabolite imaging

Bruker Nano Surfaces will hold a webinar on ‘In Vivo Visualization of Stromal Macrophages via Label-free FLIM-based Metabolite Imaging’ on March 29, 2017 at 8am PST / 11am EST / 3pm GMT.

From Bruker Nano Surfaces and Metrology 20 Mar 2017

Fat cells take over production of uridine from liver during fasting

How do mammals keep two biologically crucial metabolites in balance during times when they are feeding, sleeping, and fasting? The answer may require rewriting some textbooks.

17 Mar 2017

First physiological test opens door to early diagnosis of autism

An algorithm based on levels of metabolites found in a blood sample can accurately predict whether a child is on the Autism spectrum of disorder (ASD), based upon a recent study.

16 Mar 2017

Low levels of allopregnanolone hormone may predict risk of postpartum depression

In a small-scale study of women with previously diagnosed mood disorders, Johns Hopkins researchers report that lower levels of the hormone allopregnanolone in the second trimester of pregnancy were associated with an increased chance of developing postpartum depression in women already known to be at risk for the disorder.

14 Mar 2017

Metabolite News and Research

Further Reading

Brown fat in humans: more than previously thought

Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeutics

Study may provide insight into how R-LA promotes death of hepatoma cells

Metabolite produced by intestinal bacteria protects against type 2 diabetes, study shows

Gene CRY1 variant alters circadian clock contributing to delayed sleep phase disorder, study finds

Children's hands may carry significant levels of nicotine, study shows

Unique metabolic ‘signature’ in urine may help predict development of diabetes in obese teenagers

Pyrethroid pesticide exposure may cause earlier sexual maturity in boys

Researchers identify appetite-suppression mechanism in flies

Platforms for NMR software for spectrometer control and data analysis announced by Bruker

Sphere Medical introduces new functionality to Proxima platform for efficient critical care patient monitoring

Bruker Nano Surfaces to hold webinar on label-free FLIM-based metabolite imaging

Fat cells take over production of uridine from liver during fasting

First physiological test opens door to early diagnosis of autism

Low levels of allopregnanolone hormone may predict risk of postpartum depression

UAlberta research could open door to new therapies for diabetes patients

UVA researchers use probiotic bacteria in yogurt to reverse depression symptoms

Research provides insights on how pathogens escape process of autophagy

NR could potentially prevent chemotherapy-induced peripheral neuropathy in cancer patients

World's largest GWAS on proteomics uncovers molecular mechanisms of complex diseases

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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