Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Study highlights new approach to produce coral snake antivenom from synthetically designed DNA

Coral snake venom carries significant neurotoxicity and human injuries can be severe or even lethal. Despite this, antivenom treatments are scarce due to challenges collecting adequate amounts of venom needed to produce anti-elapidic serum. PLOS Neglected Tropical Diseases highlights exciting new research from the Butantan Institute in Brazil using synthetically designed DNA to produce coral-snake antivenom.

4 Mar 2016

Scientists track rare potent antibodies in HIV-infected individual

One of the most crucial and elusive goals of an effective HIV vaccine is to stimulate antibodies that can attack the virus even as it relentlessly mutates.

4 Mar 2016

Simple method could make early disease diagnosis much easier

Detecting diseases such as cancer in their earliest stages can make a huge difference in patient treatment, but it is often difficult to do. Now scientists report in the journal ACS Central Science a new, simple method that could make early disease diagnosis much easier.

3 Mar 2016

Omalizumab drug can be better targeted to treat people with severe asthma

Around five million people in the UK are currently being treated for asthma. Of these, a quarter of a million are unable to get good control of their condition, resulting in frequent, severe, or even life-threatening attacks. A new study brings hope to these patients by investigating whether the drug Omalizumab can be better targeted.

2 Mar 2016

Added benefit of aflibercept not proven in myopic choroidal neovascularisation

Aflibercept (trade name: Eylea) has been approved since October 2015 for adults with impaired vision due to myopic choroidal neovascularisation.

2 Mar 2016

Single antibody could hold promise as potential treatment for human cases of EVD

A single monoclonal antibody isolated from a human survivor of Ebola virus disease (EVD) completely protected monkeys from lethal infection with the virus, according to research published in today's online edition of the journal Science.

27 Feb 2016

Researchers identify, isolate and characterize two Ebola virus neutralizing monoclonal antibodies

The Institute for Research in Biomedicine, affiliated to the Università della Svizzera italiana, and Humabs BioMed SA, a Swiss antibody therapeutics company, have identified, isolated and characterized two Ebola virus neutralizing monoclonal antibodies from the blood of a survivor of an Ebola infection.

27 Feb 2016

Phase III study: Ocrelizumab significantly reduces disease activity in PPMS patients

Ocrelizumab (OCR) is a humanized monoclonal antibody that selectively targets CD20+B cells. In a randomized, double-blind, placebo-controlled Phase III study (ORATORIO), OCR significantly reduced disease activity in patients with primary progressive multiple sclerosis (PPMS).

27 Feb 2016

Research unveils standard front-line treatment for advanced ovarian cancer

Research led by a Dignity Health St. Joseph's Hospital and Medical Center physician on ovarian cancer was published in the Feb. 24, 2016 issue of New England Journal of Medicine. The research was directed by Bradley J. Monk, M.D. and researchers at 12 other medical facilities around the nation.

27 Feb 2016

Matched ChIP-validated Antibodies & Primer Sets

Chromatrap announces that its high quality ChIP-validated antibodies can now be supplied with optimised matching primer sets.

From Chromatrap® - Porvair Sciences Ltd 26 Feb 2016

Lilly announces CHMP positive opinion for ixekizumab for treatment of adults with plaque psoriasis

Eli Lilly and Company announced today that the European Medicines Agency's Committee for Medicinal Products for Human Use has issued a positive opinion for ixekizumab for the treatment of moderate-to-severe plaque psoriasis in adults in the European Union who are candidates for systemic therapy.

26 Feb 2016

Rigel begins fostamatinib Phase 2 trial for treatment of patients with autoimmune hemolytic anemia

Rigel Pharmaceuticals Inc. today announced that it has initiated a Phase 2 clinical trial to evaluate fostamatinib, its oral SYK inhibitor, as a potential treatment for autoimmune hemolytic anemia (AIHA).

25 Feb 2016

FDA-approved VENTANA anti-ALK CDx more accurate than commonly used IHC assay for patient selection

The U.S. Food and Drug Administration approved VENTANA anti-ALK(D5F3)CDx performed more accurately than another commonly used immunohistochemistry (IHC) assay, based on the use of the 5A4 clone, for the selection of patients eligible to receive ALK tyrosine kinase inhibitor (TKI) treatment.

23 Feb 2016

Romosozumab for postmenopausal women with osteoporosis meets co-primary endpoints in Phase 3 study

Amgen and UCB today announced top-line results from the Phase 3 placebo-controlled FRActure study in postmenopausal woMen with ostEoporosis (FRAME).

22 Feb 2016

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer's disease and improvements in monitoring the effects of medication.

22 Feb 2016

Researchers identify new group of powerful Ebola-fighting antibodies

A research team that included scientists from The Scripps Research Institute has identified a new group of powerful antibodies to fight Ebola virus.

22 Feb 2016

More phase II success for CGRP migraine prevention strategy

Another antibody targeting the calcitonin gene-related peptide pathway has proved successful against episodic migraine in a phase II trial.

18 Feb 2016

New treatment protects mice from MERS infection

In a new study, University of Maryland School of Medicine researchers have had promising results with a new treatment for Middle East Respiratory Syndrome (MERS). The study, published today in the journal Science Translational Medicine, found a new treatment that protected mice from MERS infection.

18 Feb 2016

Corvidia Therapeutics secures $26 million in Series A financing

Corvidia Therapeutics, a biotechnology company focused on the development of precision cardiovascular therapies, announced today that it has raised $26 million in a Series A financing, co-led by seed-investor Sofinnova Partners, and Apple Tree Partners.

18 Feb 2016

Benefit of using antibody-coated drug-eluting stents for CHD still unclear, shows report

In patients with coronary heart disease requiring a stent implantation, the benefit of treatment with antibody-coated drug-eluting stents (ABC-DES) versus drug-eluting stents without antibody coating (DES) is still unclear.

17 Feb 2016

Antibody News and Research

Further Reading

Study highlights new approach to produce coral snake antivenom from synthetically designed DNA

Scientists track rare potent antibodies in HIV-infected individual

Simple method could make early disease diagnosis much easier

Omalizumab drug can be better targeted to treat people with severe asthma

Added benefit of aflibercept not proven in myopic choroidal neovascularisation

Single antibody could hold promise as potential treatment for human cases of EVD

Researchers identify, isolate and characterize two Ebola virus neutralizing monoclonal antibodies

Phase III study: Ocrelizumab significantly reduces disease activity in PPMS patients

Research unveils standard front-line treatment for advanced ovarian cancer

Matched ChIP-validated Antibodies & Primer Sets

Lilly announces CHMP positive opinion for ixekizumab for treatment of adults with plaque psoriasis

Rigel begins fostamatinib Phase 2 trial for treatment of patients with autoimmune hemolytic anemia

FDA-approved VENTANA anti-ALK CDx more accurate than commonly used IHC assay for patient selection

Romosozumab for postmenopausal women with osteoporosis meets co-primary endpoints in Phase 3 study

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

Researchers identify new group of powerful Ebola-fighting antibodies

More phase II success for CGRP migraine prevention strategy

New treatment protects mice from MERS infection

Corvidia Therapeutics secures $26 million in Series A financing

Benefit of using antibody-coated drug-eluting stents for CHD still unclear, shows report

Immunology eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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