Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Researchers shed light on how immune cells weaken with age

Researchers from the European Bioinformatics Institute, University of Cambridge, the Wellcome Trust Sanger Institute and the Cancer Research UK–Cambridge Institute have shed light on a long-standing debate about why the immune system weakens with age.

3 Apr 2017

Researchers shed light on genome reorganization after fertilization in single-cell mammalian embryo

Using a newly developed method researchers at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences have been able to shed light on the complexity of genome reorganization occurring during the first hours after fertilization in the single-cell mammalian embryo

30 Mar 2017

Rogue proteins involved in breast cancer point to potential treatment options

For patients with difficult-to-treat cancers, doctors increasingly rely on genomic testing of tumors to identify errors in the DNA that indicate a tumor can be targeted by existing therapies.

28 Mar 2017

Insilico Medicine to present research findings in AI for drug discovery at BioDataWorld West Congress

Insilico Medicine, a Baltimore-based Big Data analytics company applying deep learning techniques to drug discovery, biomarker development and human longevity research will present and chair a panel at the BioDataWorld West, San Francisco, April 26-27.

25 Mar 2017

Genome sequencing approach opens door to therapy options for rare, neglected cancers

An international team of scientists led by the Icahn School of Medicine at Mount Sinai and UConn School of Medicine have reported the results of a genome sequencing study for an extremely rare form of cancer.

23 Mar 2017

AMP releases new guidelines for validation of NGS-based oncology panels

The Association for Molecular Pathology, the premier global, non-profit molecular diagnostics professional society, today published consensus recommendations to help clinical laboratory professionals achieve high-quality sequencing results and deliver better care for cancer patients.

22 Mar 2017

Machine learning helps researchers uncover cellular control networks

The flow of information between cells in our bodies is exceedingly complex: sensing, signaling, and influencing each other in a constant flow of microscopic engagements. These interactions are critical for life, and when they go awry can lead to the illness and injury.

22 Mar 2017

Researchers develop new method that uses gene editing to find cancer's weak spots

Genetic mutations that cause cancer also weaken cancer cells, creating an opportunity for researchers to develop drugs that will selectively kill them, while sparing normal cells.

20 Mar 2017

UT Southwestern researchers develop computer model to predict most deadly lung cancers

After evaluating more than 900 differences in the shape and structure of cancer cells, UT Southwestern Medical Center researchers developed a computer model able to predict the most deadly lung cancers based on a fraction of those features.

16 Mar 2017

Study reveals novel mutations in mucosal melanoma that may pave way for new therapies

Not all melanomas are created equal. While most melanomas appear on the skin as the result of sun exposure, a small subset of melanomas arise spontaneously from mucosal tissues.

15 Mar 2017

UB research yields neural crest cells from adult skin cells without genetic modification

A discovery, several years in the making, by a University at Buffalo research team has proven that adult skin cells can be converted into neural crest cells (a type of stem cell) without any genetic modification, and that these stem cells can yield other cells that are present in the spinal cord and the brain.

15 Mar 2017

York researchers move closer to finding new treatments for chronic bladder diseases

Using human cells, they have mapped how different proteins bind along the DNA to control which genes are active during barrier formation.

14 Mar 2017

Scientists announce landmark database of lifespan-extending drugs and compounds

Scientists from the Biogerontology Research Foundation (BGRF) and University of Liverpool have announced a landmark database of lifespan-extending drugs and compounds called DrugAge.

14 Mar 2017

Investigational RSV vaccine protects cattle from respiratory diseases

A novel vaccine developed by scientists at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, protected cattle from respiratory syncytial virus (RSV) infection, according to research published online in npj Vaccines on March 8.

10 Mar 2017

Researchers discover intestinal quiescent stem cells that are resistant to chemotherapy

The intestine has a high rate of cellular regeneration due to the wear and tear originated by its function degrading and absorbing nutrients and eliminating waste. The entire cell wall is renewed once a week approximately.

10 Mar 2017

Researchers discover genetic bases of Opitz C syndrome

Opitz C syndrome is a genetic disease that causes severe disabilities in patients and has been diagnosed in three people in the Iberian Peninsula, and sixty people in the world.

10 Mar 2017

Researchers identify new gene that can lead to sudden death among young people

Researchers from Canada, South Africa and Italy have identified a new gene that can lead to sudden death among young people and athletes.

10 Mar 2017

Deep learning transforms the drug discovery process in collaboration between Insilico Medicine and Life Extension

In March 2016 Insilico Medicine initiated a research collaboration with Life Extension to apply advanced bioinformatic methods and deep learning algorithms to screen for naturally occurring compounds that may slow down or even reverse the cellular and molecular mechanisms of aging. Today Life Extension (LE) launched a new line of nutraceuticals called GEROPROTECTTM, and the first product in the series called Ageless CellTM combines some of the natural compounds that were shortlisted by Insilico Medicine’s algorithms and are generally recognized as safe (GRAS).

7 Mar 2017

Researchers identify gene variants that may predispose individuals to develop gallbladder cancer

By comparing the genetic code of gallbladder cancer patients with those of healthy volunteers at nearly 700,000 different locations in the genome, researchers say they have found several gene variants which may predispose individuals to develop the disease.

6 Mar 2017

Case Western Reserve and VA team up to tackle rising problem of antibiotic resistance

Since the discovery of penicillin in 1928, antibiotics have made the world a much safer and healthier place. But Shakespeare was onto something when he asked if it's possible to have too much of a good thing. In the case of antibiotics, the answer is increasingly "yes."

3 Mar 2017

Bioinformatics News and Research

Further Reading

Researchers shed light on how immune cells weaken with age

Researchers shed light on genome reorganization after fertilization in single-cell mammalian embryo

Rogue proteins involved in breast cancer point to potential treatment options

Insilico Medicine to present research findings in AI for drug discovery at BioDataWorld West Congress

Genome sequencing approach opens door to therapy options for rare, neglected cancers

AMP releases new guidelines for validation of NGS-based oncology panels

Machine learning helps researchers uncover cellular control networks

Researchers develop new method that uses gene editing to find cancer's weak spots

UT Southwestern researchers develop computer model to predict most deadly lung cancers

Study reveals novel mutations in mucosal melanoma that may pave way for new therapies

UB research yields neural crest cells from adult skin cells without genetic modification

York researchers move closer to finding new treatments for chronic bladder diseases

Scientists announce landmark database of lifespan-extending drugs and compounds

Investigational RSV vaccine protects cattle from respiratory diseases

Researchers discover intestinal quiescent stem cells that are resistant to chemotherapy

Researchers discover genetic bases of Opitz C syndrome

Researchers identify new gene that can lead to sudden death among young people

Deep learning transforms the drug discovery process in collaboration between Insilico Medicine and Life Extension

Researchers identify gene variants that may predispose individuals to develop gallbladder cancer

Case Western Reserve and VA team up to tackle rising problem of antibiotic resistance

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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