Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Novel approach to pain therapy paves way for lower dosage painkillers

For patients managing cancer and other chronic health issues, painkillers such as morphine and Vicodin are often essential for pain relief. The body's natural tendency to develop tolerance to these medications, however, often requires patients to take higher doses - increasing risks of harmful side effects and dependency.

11 Jun 2013

Early intervention needed to reduce lifelong consequences in neglected or abused children

Preschool children who have been neglected or emotionally abused exhibit a range of emotional and behavioral difficulties and adverse mother-child interactions that indicate these children require prompt evaluation and interventions, according to a systematic review by Aideen Mary Naughton, M.B., B.Ch., B.A.O., D.C.H., F.R.C.P.C.H., of Public Health Wales, Pontypool, England, and colleagues.

11 Jun 2013

Stroke experts discuss benefits of endovascular therapy in treating acute ischemic stroke

Covidien, a leading global provider of healthcare products, recently brought together six of the world's prominent thought-leaders in stroke at the 2013 European Stroke Conference.

11 Jun 2013

Report shows low baseline DBP associated with brain atrophy in patients with arterial disease

Low baseline diastolic blood pressure appears to be associated with brain atrophy in patients with arterial disease, whenever declining levels of blood pressure over time among patients who had a higher baseline BP were associated with less progression of atrophy, according to a report published Online First by JAMA Neurology, a JAMA Network publication.

11 Jun 2013

Researchers find master regulator of EMT and metastasis

The predominant cause of death in cancer patients is metastasis, the formation of secondary tumors in other organs like the brain, liver, and lungs. Cancer cells detach from the original primary tumor and reach a single cell or group of cells in another organ. The cells of the body normally remain in place through adhering to an extracellular substance. However, cancer cells learn how to release themselves from these bonds and invade surrounding tissues, blood, and the lymphatic system.

11 Jun 2013

Debate over a dying child and a lack of transplant organs

Several columnists explore the difficult questions raised by the case of Sarah Murnaghan, a 10-year-old with cystic fibrosis who needs a lung transplant to survive.

10 Jun 2013

Discovery highlights protective role of liver enzyme in treating jaundice

Helping to protect newborns and older patients against more severe effects of jaundice is the hope of University of Guelph researchers, who have shown how a liver enzyme protects cells from damage caused by the condition.

10 Jun 2013

Concert Pharmaceuticals announces initiation of CTP-354 Phase 1 trial in healthy volunteers

Concert Pharmaceuticals, Inc. today announced that it has initiated a Phase 1 clinical trial with CTP-354. CTP-354 is a novel GABAA receptor subtype-selective modulator that has demonstrated no sedation at therapeutic doses in preclinical models in contrast to existing GABAA receptor non-selective agonists, such as benzodiazepines.

10 Jun 2013

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

A drug used to control Type II diabetes can help repair the spinal cords of mice suffering from the inherited disease adrenoleukodystrophy which, untreated, leads eventually to a paralysis, a vegetative state and death.

10 Jun 2013

Brain-training computer games may help restore memory and competency to forensic psychiatry patients

Brain-training computer games may help restore memory and competency to forensic psychiatry patients in state mental hospitals, researchers say.

10 Jun 2013

Blood vessels within sensory area of mammalian brain loop connect in unexpected ways, new map reveals

Blood vessels within a sensory area of the mammalian brain loop and connect in unexpected ways, a new map has revealed.

10 Jun 2013

Common antidepressant medications may impair a form of learning, new report suggests

An interesting new report of animal research published in Biological Psychiatry suggests that common antidepressant medications may impair a form of learning that is important clinically.

10 Jun 2013

Edge Therapeutics announces FDA acceptance of IND application for EG-1962

Edge Therapeutics, Inc., a clinical-stage biopharmaceutical company focused on developing and commercializing life-saving hospital products for acute, fatal or debilitating conditions, announced today that the U.S. Food and Drug Administration has accepted the Company's Investigational New Drug application for EG-1962, a novel bio-absorbable nimodipine microparticle formulation.

10 Jun 2013

Poll reveals that half of Canadians are directly touched by stroke

More Canadians are surviving strokes due to advances in awareness and medical services but a new report by the Heart and Stroke Foundation reveals that more than one-third of Canadians mistakenly believe that the recovery period is limited to a few months.

10 Jun 2013

First consensus guidelines for use of neurostimulation in chronic pain

Recognizing that treatment of chronic pain can be confounding, the Neuromodulation Appropriateness Consensus Committee, an international group of more than 60 leading pain specialists, has created the first consensus guidelines for the use of neurostimulation in chronic pain.

10 Jun 2013

International experts formulate guidance for neuromodulation practitioners

An international panel of experts has formulated guidance for neuromodulation practitioners that reflects increasing recognition of the value of this growing field.

10 Jun 2013

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

10 Jun 2013

Summa Akron City Hospital installs Toshiba's Aquilion ONE, Infinix-i systems

As a level-one trauma and accredited stroke center, time is critical at Summa Health System's Akron City Hospital, located in Akron, Ohio. To provide the highest level of patient care, the hospital installed an Aquilion ONE CT scanner and Infinix-i bi-plane cardiovascular X-ray from Toshiba America Medical Systems, Inc.

10 Jun 2013

Nation's leading experts join forces to accelerate effective treatments for brain tumors

The nation's leading brain tumor and biotech industry experts again joined forces Friday, June 7, in a bid to accelerate more effective treatments for brain tumors and promote funding for the latest emerging therapies, as the Weill Cornell Brain and Spine Center and Voices Against Brain Cancer hosted its second annual Brain Tumor Biotech Summit.

10 Jun 2013

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

By applying light stimulation to highly specific neurons in the brain, the researchers managed to re-establish normal behaviour in mice that had beforehand presented pathological repetitive behaviour similar to that observed in human patients suffering from obsessive-compulsive disorders.

10 Jun 2013

Brain News and Research

Further Reading

Novel approach to pain therapy paves way for lower dosage painkillers

Early intervention needed to reduce lifelong consequences in neglected or abused children

Stroke experts discuss benefits of endovascular therapy in treating acute ischemic stroke

Report shows low baseline DBP associated with brain atrophy in patients with arterial disease

Researchers find master regulator of EMT and metastasis

Debate over a dying child and a lack of transplant organs

Discovery highlights protective role of liver enzyme in treating jaundice

Concert Pharmaceuticals announces initiation of CTP-354 Phase 1 trial in healthy volunteers

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

Brain-training computer games may help restore memory and competency to forensic psychiatry patients

Blood vessels within sensory area of mammalian brain loop connect in unexpected ways, new map reveals

Common antidepressant medications may impair a form of learning, new report suggests

Edge Therapeutics announces FDA acceptance of IND application for EG-1962

Poll reveals that half of Canadians are directly touched by stroke

First consensus guidelines for use of neurostimulation in chronic pain

International experts formulate guidance for neuromodulation practitioners

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Summa Akron City Hospital installs Toshiba's Aquilion ONE, Infinix-i systems

Nation's leading experts join forces to accelerate effective treatments for brain tumors

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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