Crohn's Disease News and Research

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Crohn’s disease is a chronic inflammatory disease of the bowel affecting at least 115,000 people in the UK. The condition usually develops in teenagers and young adults, but can be diagnosed at any age and is equally common in men and women.

The condition can affect any part of the digestive tract between the mouth and the anus, although inflammation in the last section of the small bowel (ileum) or the first part of the large bowel (colon) is most common.

Crohn's disease is a ‘relapsing and remitting’ condition characterized by symptom-free periods followed by episodes of “flare-ups,” during which symptoms such as diarrhoea, abdominal pain, fever and fatigue may become particularly bothersome.

Long term, severe inflammation can damage sections of the digestive system, resulting in additional complications, such as a tear in the wall of the anus (fissure), narrowing of the intestine (stricture) or the formation of an abnormal connection between the bowel and another body part such as the bladder, vagina or skin (fistula). Such problems usually require surgical treatment to correct. Crohn's disease also increases the risk of developing bowel cancer.

The exact cause of Crohn's disease is not clear but experts believe a combination of factors may be at work including genetics, immune responses to certain bacteria or viruses and lifestyle factors such as diet or smoking status.
Cornell researchers develop chemical probe activated by UV light to control inflammation

Cornell researchers develop chemical probe activated by UV light to control inflammation

Early life history and genetics may play crucial role in shaping gut microbiome

Early life history and genetics may play crucial role in shaping gut microbiome

DNA changes in blood samples could pave way for simple tests to diagnose IBD

DNA changes in blood samples could pave way for simple tests to diagnose IBD

New research shows immune paralysis in sepsis patients can be reversed

New research shows immune paralysis in sepsis patients can be reversed

Arthritis drug induces response and remission in patients with Crohn's disease, study finds

Arthritis drug induces response and remission in patients with Crohn's disease, study finds

FDA approves new assay for diagnosis of IBD

FDA approves new assay for diagnosis of IBD

CannaCure Florida offers medical cannabis educational conference following legalization of marijuana

CannaCure Florida offers medical cannabis educational conference following legalization of marijuana

Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Researchers create new culture model of human intestine to study inflammatory bowel disease

Researchers create new culture model of human intestine to study inflammatory bowel disease

Many ulcerative colitis patients with anemia do not receive testing and treatment, study reports

Many ulcerative colitis patients with anemia do not receive testing and treatment, study reports

Esperite's business unit develops therapy for Crohn's disease perianal fistulas

Esperite's business unit develops therapy for Crohn's disease perianal fistulas

Researchers identify genomic regions linked to ulcerative colitis in African-Americans

Researchers identify genomic regions linked to ulcerative colitis in African-Americans

IBD diagnosis in childhood does not affect educational achievements and lifestyle, study finds

IBD diagnosis in childhood does not affect educational achievements and lifestyle, study finds

Anti-inflammatory drugs may improve severity of depressive symptoms, study finds

Anti-inflammatory drugs may improve severity of depressive symptoms, study finds

Scientists at NIH and Emory University induce sustained remission in SIV-infected monkeys

Scientists at NIH and Emory University induce sustained remission in SIV-infected monkeys

Crohn's disease appears to have two distinct genetic subtypes, study finds

Crohn's disease appears to have two distinct genetic subtypes, study finds

Common food-poisoning bacteria linked to increased risk of Crohn's disease

Common food-poisoning bacteria linked to increased risk of Crohn's disease

Researchers to investigate similarities between Crohn's and Johne's disease that affects cattle

Researchers to investigate similarities between Crohn's and Johne's disease that affects cattle

Scientists reveal molecular elements that bridge anxiety and metabolism

Scientists reveal molecular elements that bridge anxiety and metabolism

FDA approves new biosimilar for multiple inflammatory diseases

FDA approves new biosimilar for multiple inflammatory diseases