Crohn's Disease News and Research RSS Feed - Crohn's Disease News and Research

Crohn's disease is a chronic, progressive, destructive disorder that causes inflammation of the gastrointestinal (GI) tract, most commonly at the end of the small intestine (the ileum) and beginning of the large intestine (the colon). If not effectively treated, it results in the need for surgery. Crohn's disease has been estimated to affect as many as half a million Americans. People with Crohn's can experience an ongoing cycle of flare-up and remission throughout their lives. Together with ulcerative colitis, Crohn's disease is an inflammatory bowel disease (IBD).
Phase IIa study shows safety and efficacy of BL-7040 in treating ulcerative colitis

Phase IIa study shows safety and efficacy of BL-7040 in treating ulcerative colitis

BioLineRx, a biopharmaceutical development company, announced today positive Phase IIa results for BL-7040, an orally available drug for treating inflammatory bowel disease. [More]
AARDA creates new multi-media public service campaign for AD patients

AARDA creates new multi-media public service campaign for AD patients

In response to a recent study that found roughly one-third of prescriptions for autoimmune disease patients go unfilled and a high level of physician mistrust exists among AD patients, the American Autoimmune Related Diseases Association, Inc. has created a new multi-media public service campaign with tools designed to help patients make informed decisions about newly-prescribed therapies and treatments. [More]
New data on T cells' protective role suggests need for new approach to dengue vaccine design

New data on T cells' protective role suggests need for new approach to dengue vaccine design

As efforts to create a strong and effective vaccine for the dreaded dengue virus continue to hit snags, a new study from researchers at the La Jolla Institute for Allergy & Immunology offers surprising evidence that suggests the need for a revamped approach to dengue vaccine design. [More]

Researchers use atomic force microscopy technique to read information encoded in gut lining

A new technique based on atomic force microscopy was developed at the Institute of Food Research to help 'read' information encoded in the gut lining. [More]
New study shows exposure to tobacco smoke could negatively impact adolescent kidney function

New study shows exposure to tobacco smoke could negatively impact adolescent kidney function

Exposure to tobacco smoke could negatively impact adolescent kidney function; this is according to a new study led by a team of researchers at the Johns Hopkins Bloomberg School of Public Health and the Johns Hopkins Children's Center. [More]
Nektar Therapeutics presents positive results for NKTR-214 at AACR Annual Meeting

Nektar Therapeutics presents positive results for NKTR-214 at AACR Annual Meeting

Nektar Therapeutics today presented positive preclinical data for NKTR-214, a novel cancer immunotherapy which targets the IL-2 receptor complex, at the 2013 American Association for Cancer Research Annual Meeting. [More]
UC San Francisco researchers outline cell-based therapeutics as a "third pillar” of medicine

UC San Francisco researchers outline cell-based therapeutics as a "third pillar” of medicine

Treating patients with cells may one day become as common as it is now to treat the sick with drugs made from engineered proteins, antibodies or smaller chemicals, according to UC San Francisco researchers. [More]

Same factor that helps fight off severe inflammatory ailments also functions as enemy

The same factor in our immune system that is instrumental in enabling us to fight off severe and dangerous inflammatory ailments is also a player in doing the opposite at a later stage, causing the suppression of our immune response. [More]
Ulcerative colitis and Crohn’s disease treatments: an interview with Dr Parikh, vice president, general medicine, Takeda

Ulcerative colitis and Crohn’s disease treatments: an interview with Dr Parikh, vice president, general medicine, Takeda

Ulcerative colitis (UC) and Crohn’s disease (CD) are both relapsing and remitting chronic diseases of bowel inflammation. By that I mean they flare and physicians try to get the flare under control and try to induce remission. However, despite a number of treatments available, they tend to relapse. [More]
LabCorp launches expanded IBD testing profile

LabCorp launches expanded IBD testing profile

Laboratory Corporation of America Holdings announced today the availability of an expanded testing menu to help clinicians diagnose, treat and monitor the course of Inflammatory Bowel Disease. [More]
FDA clears Soligenix's IND application for SGX942 for treatment of oral mucositis

FDA clears Soligenix's IND application for SGX942 for treatment of oral mucositis

Soligenix, Inc., a clinical stage biopharmaceutical company, announced today that the Food and Drug Administration has completed its review and cleared the Investigational New Drug application for SGX942 for the treatment of oral mucositis resulting from radiation and/or chemotherapy treatment in head and neck cancer patients. [More]
Researchers study gene variants that bear signature for inflammatory disease susceptibility

Researchers study gene variants that bear signature for inflammatory disease susceptibility

In new research published in the April 4, 2013 issue of The American Journal of Human Genetics, researchers from Brigham and Women's Hospital demonstrate that some variants in our genes that could put a person at risk for inflammatory diseases such as multiple sclerosis, Crohn's disease or rheumatoid arthritis, have been the target of natural selection over the course of human history. [More]

Experts outline new agenda for inflammatory bowel disease research

Every five years, the Crohn's & Colitis Foundation of America gathers top researchers in inflammatory bowel disease to set the research agenda for the next five years. [More]
Cytomegalovirus employs a novel trick to hide from immune detection

Cytomegalovirus employs a novel trick to hide from immune detection

A virus that most people have probably never heard of, yet most of us carry, is the number 1 infectious cause of congenital birth defects. One in 750 children are born with, or develop, permanent disabilities such as hearing loss or brain damage as a result of CMV (cytomegalovirus) infection in the womb. [More]
AARDA launches 2013 Autoimmune Walk: Linking Together for a Cure Campaign calendar

AARDA launches 2013 Autoimmune Walk: Linking Together for a Cure Campaign calendar

As part of its National Autoimmune Disease Awareness Month activities, American Autoimmune Related Diseases Association has launched its 2013 "Autoimmune Walk: Linking Together for a Cure" Campaign calendar with more than double the number of events taking place this year from New York to California. [More]

Research finding aids efforts toward cytomegalovirus vaccine

A virus most people probably have never heard of, but that the majority of us carry, is the No. 1 infectious cause of congenital birth defects in the U.S. today. Because of cytomegalovirus (CMV) infection during in utero development, 1 in 750 children are born with or develop permanent disabilities such as hearing loss or brain damage. [More]
Investigational treatment for ulcerative colitis (UC) and Crohn’s disease (CD) has Marketing Authorisation Application submitted

Investigational treatment for ulcerative colitis (UC) and Crohn’s disease (CD) has Marketing Authorisation Application submitted

Takeda Pharmaceutical Company Limited (“Takeda”) today announced that a Marketing Authorisation Application (MAA) has been submitted to The European Medicines Agency (EMA) for vedolizumab, an investigational, gut-selective humanized monoclonal antibody for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn’s disease (CD), the two most common types of inflammatory bowel disease (IBD). [More]

University of Manchester leads systems medicine research network for inflammatory bowel disease

The University of Manchester is leading a €12 million systems medicine research network to identify better treatments for Inflammatory Bowel Disease like Crohn's Disease. [More]
Eating your greens may be even more important than previously thought

Eating your greens may be even more important than previously thought

Eating your greens may be even more important than previously thought, with the discovery that an immune cell population essential for intestinal health could be controlled by leafy greens in your diet. [More]
No increased risk for inflammatory bowel disease with isotretinoin

No increased risk for inflammatory bowel disease with isotretinoin

Researchers report no link between isotretinoin use for the treatment of acne and increased risk for inflammatory bowel disease in women of reproductive age. [More]