Endocrinology News and Research RSS Feed - Endocrinology News and Research

Endocrinology is a branch of medicine dealing with disorder of the endocrine system and its specific secretions called hormones, the integration of developmental events such as proliferation, growth, and differentiation (including histogenesis and organogenesis) and the coordination of metabolism, respiration, excretion, movement, reproduction, and sensory perception depend on chemical cues, substances synthesised and secreted by specialized cells.
Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Bioenergetic analysis of pancreatic beta-cells shows impaired metabolic signature in type 2 diabetes patients

Impaired activation of mitochondrial energy metabolism in the presence of glucose has been demonstrated in pancreatic beta-cells from patients with type 2 diabetes. The cause of this dysfunction has been unknown. Publishing online in Endocrinology, Buck Institute assistant research professor Akos Gerencser, PhD, shows that in patients with type 2 diabetes the balance between supply and demand of the mitochondrial membrane potential (ΔψM) is altered causing a decrease in the signaling that turns on insulin secretion. [More]
Low blood level of 4 proteins can help diabetics protect against immune attack

Low blood level of 4 proteins can help diabetics protect against immune attack

Patients with type 1 diabetes have significantly lower blood levels of four proteins that help protect their tissue from attack by their immune system, scientists report. [More]
Endocrine Society recommends removal of tumor as first-line treatment for endogenous Cushing's syndrome

Endocrine Society recommends removal of tumor as first-line treatment for endogenous Cushing's syndrome

The Endocrine Society today issued a Clinical Practice Guideline (CPG) on strategies for treating Cushing's syndrome, a condition caused by overexposure to the hormone cortisol. [More]
Aeterna Zentaris selects optimized Erk inhibitor molecule for further development

Aeterna Zentaris selects optimized Erk inhibitor molecule for further development

Aeterna Zentaris Inc. today announced it has selected an optimized Erk inhibitor molecule for development, thus achieving another important milestone in the development of a new class of potential cancer therapies. [More]
German life sciences entrepreneurs granted option to develop Aeterna Zentaris’ oral allogenic tumor vaccine technology

German life sciences entrepreneurs granted option to develop Aeterna Zentaris’ oral allogenic tumor vaccine technology

Aeterna Zentaris Inc. today announced that it has granted to German life sciences entrepreneurs with a proven track-record of funding the development and commercialization of biotechnology, an option to license the Company's live recombinant oral allogenic tumor vaccine technology, including AEZS-120, the most advanced product candidate for prostate cancer which is ready to enter a Phase 1 clinical trial. [More]
Biologists identify genetic mechanisms behind anti-inflammatory impact of cortisone

Biologists identify genetic mechanisms behind anti-inflammatory impact of cortisone

There's no time to lose when an emergency doctor diagnoses „Shock lung!" at the accident scene. What physicians know as "acute lung injury" (ALI) otherwise leads to death by suffocation without immediate treatment. [More]
New book provides overview of treatment options for paediatric calcium and bone disorders

New book provides overview of treatment options for paediatric calcium and bone disorders

Knowledge about paediatric calcium and bone disorders has increased rapidly over the past twenty years. Great advances have been made in the underlying genetic basis for many conditions, in bone density and geometry imaging and in the development of new treatment options, calling for a new edition of 'Calcium and Bone Disorders in Children and Adolescents' which was first published in 2009. [More]
Endocrine Society selects 18 endocrinologists as winners of 2016 Laureate Awards

Endocrine Society selects 18 endocrinologists as winners of 2016 Laureate Awards

The Endocrine Society today announced it has chosen 18 accomplished endocrinologists as winners of the organization's prestigious 2016 Laureate Awards. [More]
Mayo Clinic researchers study HDAC inhibitors to find effective treatments for anaplastic thyroid cancer

Mayo Clinic researchers study HDAC inhibitors to find effective treatments for anaplastic thyroid cancer

In their bid to find the best combination of therapies to treat anaplastic thyroid cancer (ATC), researchers on Mayo Clinic's Florida campus demonstrated that all histone deacetylase (HDAC) inhibitors are not created equal. [More]
Mediterranean lifestyle contributes to positive effects on cardiovascular health

Mediterranean lifestyle contributes to positive effects on cardiovascular health

Cardiovascular disease remains the No. 1 cause of death in the U.S. Evidence suggests that elevated levels of triglycerides (fats) in the blood after meals, known as postprandial lipemia (PPL), is associated with an increased risk for hardening of the arteries—a risk factor for cardiovascular disease. [More]
Late- and post-menopausal women have more fat around hearts compared to pre-menopausal counterparts

Late- and post-menopausal women have more fat around hearts compared to pre-menopausal counterparts

Late- and post-menopausal women have significantly greater volumes of fat around their hearts - a risk factor for heart disease - than their pre-menopausal counterparts, a University of Pittsburgh Graduate School of Public Health study has shown for the first time. [More]
UCLA Health's hospitals named among nation's best in U.S. News and World Report

UCLA Health's hospitals named among nation's best in U.S. News and World Report

UCLA Health's hospitals in Westwood and Santa Monica have been named to U.S. News and World Report's 2015-2016 Best Hospitals Honor Roll. UCLA, which previously ranked No. 5 in the country, tied for No. 3 this year. [More]
Losing single night of sleep could alter genes that control biological clocks in cells

Losing single night of sleep could alter genes that control biological clocks in cells

Swedish researchers at Uppsala University and the Karolinska Institute have found that genes that control the biological clocks in cells throughout the body are altered after losing a single night of sleep, in a study that is to be published in the Journal of Clinical Endocrinology and Metabolism. [More]
UC San Diego Health ranked again among nation's best hospitals by U.S. News & World Report

UC San Diego Health ranked again among nation's best hospitals by U.S. News & World Report

Once again, UC San Diego Health and its hospitals are ranked #1 in San Diego, and recognized among the best in the nation, by U.S. News & World Report for 2015-16. The annual U.S. News "Best Hospitals" rankings distinguish hospitals that excel in treating the most challenging health conditions. [More]
UMass Amherst scientist to study how estrogen-mimicking chemicals in the womb can increase breast cancer risk

UMass Amherst scientist to study how estrogen-mimicking chemicals in the womb can increase breast cancer risk

Much attention has been paid to genetics in breast cancer as disease rates rise, but most women have no family history of the disease, suggesting that there is an environmental risk we don't yet understand, says environmental health scientist Laura Vandenberg in the School of Public Health and Health Sciences at the University of Massachusetts Amherst. [More]
Diabetes drug metformin does not stop babies from being born overweight

Diabetes drug metformin does not stop babies from being born overweight

Treating obese pregnant women with a diabetes drug does not stop their babies from being born overweight, a study has found. [More]
BP levels declined among US children and adolescents during the past decade

BP levels declined among US children and adolescents during the past decade

Childhood high blood pressure (HBP) is a serious public health challenge worldwide due to associated increases in risk of end organ damages and correlation with HBP in adulthood. The prevalence of elevated blood pressure (BP) has been reported to increase significantly among United States children and adolescents from 1988-1994 to 1999-2008, but little is known about recent trends in BP values and elevated BP. [More]
New McLane Children's video visit program allows patients to connect with doctor from their home

New McLane Children's video visit program allows patients to connect with doctor from their home

McLane Children's, part of Baylor Scott & White Health, is piloting a new video visit program that allows patients who live far from the hospital to see their physician from the comfort of their own home. The program has successfully completed video visits with patients as far away as West Texas and the Rio Grande Valley. [More]
MGH investigators report that medication could augment benefits of bariatric surgery

MGH investigators report that medication could augment benefits of bariatric surgery

New findings about the mechanisms involved - or not involved - in the effects of the most common form of bariatric surgery suggest that combining surgery with a specific type of medication could augment the benefits of the procedure. In a report that has been published online in the journal Endocrinology, Massachusetts General Hospital investigators report that the effects of Roux-en-Y gastric bypass (RYGB) do not utilize neurologic pathways controlled by the serotonin 2C receptor. [More]
Chemicals used in plastics linked to increased risk of high blood pressure, diabetes in children and adolescents

Chemicals used in plastics linked to increased risk of high blood pressure, diabetes in children and adolescents

According to a new series of studies out of NYU Langone Medical Center, two chemicals increasingly used during manufacturing to strengthen plastic wrap, soap, cosmetics, and processed food containers have been linked to a rise in risk of high blood pressure and diabetes in children and adolescents. [More]
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