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Epilepsy is a group of disorders marked by problems in the normal functioning of the brain. These problems can produce seizures, unusual body movements, a loss of consciousness or changes in consciousness, as well as mental problems or problems with the senses.
Retigabine drug shows promise in protecting the brain against effects of ischemic stroke

Retigabine drug shows promise in protecting the brain against effects of ischemic stroke

Retigabine, a drug approved to treat epilepsy, protected the brain against the effects of ischemic stroke in a study conducted at The University of Texas Health Science Center at San Antonio. [More]
UB neurologist examines neurological disorders of U.S. presidents

UB neurologist examines neurological disorders of U.S. presidents

Neurology and history may sound like two fields that don't often overlap, but they have, sometimes with extraordinary consequences, according to a University at Buffalo neurologist. [More]
Scientists show pattern of connectivity in newly-generated hippocampal neurons

Scientists show pattern of connectivity in newly-generated hippocampal neurons

Research by a team of scientists from Cologne, Munich and Mainz has shown an unprecedented degree of connectivity reorganization in newly-generated hippocampal neurons in response to experience, suggesting their direct contribution to the processing of complex information in the adult brain. [More]
Study explores effects of medical marijuana in children and teens with ASD, ADHD

Study explores effects of medical marijuana in children and teens with ASD, ADHD

As medical marijuana becomes increasingly accepted, there is growing interest in its use for children and adolescents with developmental and behavioral problems such as autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD), according to a review in the February Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics. [More]
Retigabine drug could reduce debilitating impact of strokes

Retigabine drug could reduce debilitating impact of strokes

New research suggests that an already-approved drug could dramatically reduce the debilitating impact of strokes, which affect nearly a million Americans every year. [More]
Whole exome sequencing helps Mayo Clinic neurologist solve a medical mystery

Whole exome sequencing helps Mayo Clinic neurologist solve a medical mystery

Precision medicine is getting a jump-start from a new national initiative announced in President Obama's State of the Union message. One Georgia family has already experienced its benefits: genomic testing called whole exome sequencing helped Mayo Clinic neurologist Zbigniew Wszolek, M.D., solve a medical mystery that had left a boy with painful, jerking spasms that at times prevented him from walking or talking. [More]
People's perceptions of cost of drug may affect how much they benefit from it

People's perceptions of cost of drug may affect how much they benefit from it

People's perceptions of the cost of a drug may affect how much they benefit from the drug, even when they are receiving only a placebo, according to a new study of people with Parkinson's disease published in the January 28, 2015 online issue of Neurology®, the medical journal of the American Academy of Neurology. [More]
Prone position linked to epilepsy sudden death risk

Prone position linked to epilepsy sudden death risk

Around three-quarters of patients who have a sudden unexpected death in epilepsy are found lying in the prone position, show meta-analysis findings. [More]
electroCore’s non-invasive vagus nerve stimulation therapy safe, effective across a variety of conditions

electroCore’s non-invasive vagus nerve stimulation therapy safe, effective across a variety of conditions

Non-invasive vagus nerve stimulation (nVNS) ‘improves the safety and tolerability of VNS making it more accessible and facilitating further investigations across a wide range of uses when compared with surgically implanted VNS’ according to a review in the European Journal of Neurology. [More]
Researchers discover novel compound that helps curtail progression of temporal lobe epilepsy

Researchers discover novel compound that helps curtail progression of temporal lobe epilepsy

Researchers at the LSU Health New Orleans Neuroscience Center of Excellence have found that a novel compound they discovered helps curtail the onset and progression of temporal lobe epilepsy. [More]
ADDF awards grant to support initiation of AGB101 Phase 3 trial for aMCI treatment

ADDF awards grant to support initiation of AGB101 Phase 3 trial for aMCI treatment

The Alzheimer's Drug Discovery Foundation announced today a $900,000 grant to AgeneBio, a pharmaceutical company developing innovative therapies for neurologic and psychiatric diseases. The grant will support the initiation of an FDA-registered Phase 3 clinical trial of AGB101, a new therapeutic treatment for amnestic mild cognitive impairment (aMCI). [More]
New survey finds long-term benefits of brain surgery in patients with epilepsy

New survey finds long-term benefits of brain surgery in patients with epilepsy

Brain surgery for otherwise hard-to-treat epilepsy is effective for up to 15 years, according to a new survey by Henry Ford Hospital physicians. [More]
International scientists take new path in epilepsy research

International scientists take new path in epilepsy research

An international team of scientists together with the University of Bonn Hospital have taken a new path in the research into causes of epilepsy: The researchers determined the networks of the active genes and, like a dragnet, looked for the "main perpetrators" using a computer model. [More]
Study uses 'systems genetics' approach to identify potential target for epilepsy

Study uses 'systems genetics' approach to identify potential target for epilepsy

A single gene that coordinates a network of about 400 genes involved in epilepsy could be a target for new treatments, according to research. [More]
International study identifies genetic factors that influence the size of brain structures

International study identifies genetic factors that influence the size of brain structures

An international study, which included researchers from NUI Galway, has identified significant genetic factors that influence the size of structures within the brain. It is hoped these new insights may help scientists better understand disorders such as schizophrenia, Alzheimer's disease and epilepsy. [More]
UCLA researchers find new treatment that restores normal social behavior in autism mice model

UCLA researchers find new treatment that restores normal social behavior in autism mice model

Among the problems people with Autism spectrum disorders (ASD) struggle with are difficulties with social behavior and communication. That can translate to an inability to make friends, engage in routine conversations, or pick up on the social cues that are second nature to most people. Similarly, in a mouse model of ASD, the animals, like humans, show little interest in interacting or socializing with other mice. [More]
Alexza begins Phase 2a study of AZ-002 for ARS-related epilepsy management

Alexza begins Phase 2a study of AZ-002 for ARS-related epilepsy management

Alexza Pharmaceuticals, Inc. announced today that it has initiated a Phase 2a study of AZ-002 (Staccato alprazolam), which is being developed for the management of epilepsy in patients with acute repetitive seizures (ARS). [More]
Study leads to discovery of rare genetic disorder

Study leads to discovery of rare genetic disorder

Recently, a grassroots effort initiated by families and clinicians led to the discovery of a human genetic disorder with severe consequences that is linked to a mutation in the human NGLY1 gene. In a big step towards understanding the effects of this mutation, research by scientists at the RIKEN-Max Planck Joint Research Center in Japan implicates the enzyme ENGase as the factor responsible for deficient protein degradation that occurs in the absence of mouse Ngly1 gene expression. [More]
Could déjà vu be linked to anxiety?

Could déjà vu be linked to anxiety?

A psychology expert from Sheffield Hallam University has reported what could be the first case of a person experiencing persistent déjà vu stemming from anxiety. [More]
Endocrine Society issues guideline on prescribing drugs to manage obesity, promote weight loss

Endocrine Society issues guideline on prescribing drugs to manage obesity, promote weight loss

The Endocrine Society today issued a Clinical Practice Guideline (CPG) on strategies for prescribing drugs to manage obesity and promote weight loss. [More]