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LixiLan-O Phase III clinical trial meets primary endpoint in patients with type 2 diabetes

LixiLan-O Phase III clinical trial meets primary endpoint in patients with type 2 diabetes

Sanofi announced today that the LixiLan-O Phase III clinical trial met its primary objective in patients with type 2 diabetes treated with metformin. The fixed-ratio combination of insulin glargine 100 units/mL and lixisenatide, a GLP-1 RA, demonstrated statistically superior reduction in HbA1c (average blood glucose over the previous three months) compared with lixisenatide and compared with insulin glargine 100 units/mL. [More]
Study could pave way for more targeted treatments for individuals with brain disorders

Study could pave way for more targeted treatments for individuals with brain disorders

Like Duke Ellington's 1931 jazz standard, the human brain improvises while its rhythm section keeps up a steady beat. But when it comes to taking on intellectually challenging tasks, groups of neurons tune in to one another for a fraction of a second and harmonize, then go back to improvising, according to new research led by UC Berkeley. [More]
High-intensity interval training effective for arthritis patients

High-intensity interval training effective for arthritis patients

It's a disease that sneaks up on you. Fingers and toes slowly but surely become stiff and painful. A nice morning stretch is no longer all it takes to get your body moving. Arthritis is a chronic illness that sinks its claws into your body, and causes inflammation in your joints. [More]
New UNSW research shows high-fat maternal diet changes tastebuds of newborn's heart

New UNSW research shows high-fat maternal diet changes tastebuds of newborn's heart

Baby rats whose mothers were fed a high-fat diet had larger than normal hearts with fewer taste receptors for bitter flavours, according to new UNSW research. [More]
Hormones play dual role in unethical behavior

Hormones play dual role in unethical behavior

Hormones play a two-part role in encouraging and reinforcing cheating and other unethical behavior, according to research from Harvard University and The University of Texas at Austin. [More]
Resistance training can help reduce liver fat levels in patients suffering from fatty liver disease

Resistance training can help reduce liver fat levels in patients suffering from fatty liver disease

Resistance training in the gym leads to a fall in liver fat levels. This is the finding of a new study held at the University of Haifa in cooperation with Tel Aviv Medical Center and Tel Aviv University. [More]
New Iowa State study finds strong link between insulin resistance and increased Alzheimer's disease risk

New Iowa State study finds strong link between insulin resistance and increased Alzheimer's disease risk

The fact that obesity increases the risk of cardiovascular disease and some cancers is well known. But a new Iowa State University study adds to the growing evidence that memory loss should also be a top concern. [More]
Researchers confirm neural efficiency hypothesis

Researchers confirm neural efficiency hypothesis

The brains of more intelligent people are capable of solving tasks more efficiently, which is why these people have superior cognitive faculties, or as Elsbeth Stern, Professor for Research on Learning and Instruction at ETH Zurich, puts it: "when a more and a less intelligent person are given the same task, the more intelligent person requires less cortical activation to solve the task." [More]
Research findings may provide new approach to treating male infertility

Research findings may provide new approach to treating male infertility

A team of researchers from the National University of Singapore's (NUS) Yong Loo Lin School of Medicine has demonstrated for the first time that hydrogen sulphide (H2S), when applied exogenously, could protect testicular germ cells, which are male reproductive cells, against heat-induced injury, which is one of the major causes of male infertility. [More]
Scientists develop exercise mimic molecule that could help treat type 2 diabetes and obesity

Scientists develop exercise mimic molecule that could help treat type 2 diabetes and obesity

Scientists from the University of Southampton have developed a molecule that acts as an exercise mimic, which could potentially help treat type 2 diabetes and obesity. [More]
The Real Viking Brothers develop one-of-a-kind fitness regimen

The Real Viking Brothers develop one-of-a-kind fitness regimen

Chances are The Real Viking Brothers look at rocks differently than most. This pair of health extremists are taking fitness to the great outdoors and back in time about one thousand years. As featured in the August 2015 issue of Maxim magazine, the Real Viking Brothers a.k.a. Los Angeles actors Jacob Peacock and Paul Duke, have developed a fitness regime that replicates the highly physical lifestyle of their burly, seafaring namesakes. [More]
Girls are born with weaker spines compared to boys, study finds

Girls are born with weaker spines compared to boys, study finds

Looking at measurements of the vertebrae - the series of small bones that make up the spinal column - in newborn children, investigators at Children's Hospital Los Angeles found that differences between the sexes are present at birth. Results of the study, now online in advance of publication in the August issue of the Journal of Pediatrics, suggest that this difference is evolutionary, allowing the female spine to adapt to the fetal load during pregnancy. [More]
Study examines possible new approaches to improve health and quality of life for people with MS

Study examines possible new approaches to improve health and quality of life for people with MS

The physical symptoms of weakness and fatigue from multiple sclerosis (MS) can rock a person's confidence and ability to engage in what he or she feels is important, from being a good parent and friend to taking up a hobby, according to Matthew Plow, assistant professor from Case Western Reserve University's Frances Payne Bolton School of Nursing. [More]
Regular exercise, healthy diet may help reduce knee pain for overweight adults with diabetes

Regular exercise, healthy diet may help reduce knee pain for overweight adults with diabetes

Knee pain in older adults, often caused by osteoarthritis, usually means more visits to the doctor and also can be a harbinger of disability. [More]
Helping fight summer obesity spike among children

Helping fight summer obesity spike among children

In the fight against childhood obesity, summer is one of the most challenging times of the year. [More]

HOPE VI community revitalization project motivates exercise in Birmingham, Ala., neighborhood

When the HOPE VI community revitalization project in the disadvantaged Birmingham, Ala., neighborhood of Ensley reached the phase of building walking and biking paths, green spaces, and improved lighting in 2010, two things happened, according to a new study: First, residents developed specific expectations that leisure exercise would become more plausible, and then they followed through and got out there. [More]
Men gain weight after they become dads, new Northwestern Medicine study finds

Men gain weight after they become dads, new Northwestern Medicine study finds

All those leftover pizza crusts you snatch from your kids' plates add up. Men gain weight after they become fathers for the first time whether or not they live with their children, reports a large, new Northwestern Medicine study that tracked the weight of more than 10,000 men from adolescence to young adulthood. [More]
Duke study finds that gut worms can protect babies' brains from chronic inflammation

Duke study finds that gut worms can protect babies' brains from chronic inflammation

A Duke University study in rats finds that gut worms can protect babies' brains from long-term learning and memory problems caused by newborn infections. [More]
Postmenopausal adiposity benefits with increasing aerobic exercise

Postmenopausal adiposity benefits with increasing aerobic exercise

An aerobic exercise regimen of 300 min/week versus 150 min/week significantly improves adiposity outcomes among postmenopausal women, shows research published in JAMA Oncology. [More]
Study show that putting tax on sugary drinks could help reduce prevalence of obesity in the UK

Study show that putting tax on sugary drinks could help reduce prevalence of obesity in the UK

In today's report, the Scientific Advisory Committee on Nutrition says no more than five per cent of daily calories should come from added sugar - about seven level teaspoons. The British Medical Association has called a 20 per cent tax on sugar because, according to its figures, poor diets are causing around 70,000 premature deaths each year. [More]
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