Flow Cytometry News and Research

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Flow cytometry is a technique for counting and examining microscopic particles suspended in a stream of fluid. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus.

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

A recent study illustrated the enhanced distinct clustering of pseudotyped particles (PPs) expressing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant.

12 Apr 2022

The effect of unsuppressed HIV on T-cell response to COVID-19

A new study evaluates the impact of HIV infection on SARS-CoV-2 T-cell responses during the first and second waves of COVID-19 in South Africa.

10 Apr 2022

Shared gene expression signatures in type 1 diabetics treated with IL-2 and COVID-19 patients

Researchers assess the impact of interval administration of LD-IL-2 was examined in 18 T1D patients who received a three-day dosing interval.

10 Apr 2022

Study characterizes SARS-CoV-2 spike-specific cluster of differentiation 4+ T-cell response

In a new study, researchers characterized over 100 SARS-CoV-2-specific CD4+ T-cell epitopes.

8 Apr 2022

Transcriptional reprogramming of monocytes in COVID-19

In a recent study posted to the bioRxiv* server, researchers examined the functionality of cluster of differentiation 14-positive (CD14+) monocytes in patients with mild or moderate coronavirus disease 2019 (COVID-19).

7 Apr 2022

Phenotypic changes in monocytes from COVID-19 patients

Researchers investigate monocytes to better understand how infection with SARS-CoV-2 can cause dysfunction in these immune cells.

5 Apr 2022

SARS-CoV-2 Omicron breakthrough infections induce antibodies with cross-variant neutralization potential and recall memory B cells

Researchers reported breakthrough infections by SARS-CoV-2’s new variant of concern, Omicron, that elicited broadly cross-reactive neutralizing antibodies in the BNT162b2-vaccinated individuals.

5 Apr 2022

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1, a myeloid cell-specific receptor, in facilitating SARS-CoV-2 infection of ACE2-deficient macrophages and its effect on pro-inflammatory cytokine expression.

1 Apr 2022

Scientists explore impact of SARS-CoV-2 natural immunity on vaccine-induced immunity

A new study investigated the impact of pre-existing SARS-CoV-2 infection-induced immunity on vaccine-induced immunity.

31 Mar 2022

Study determines the molecular signatures of monocytes and regulatory T cells in the circulating blood of COVID-19 patients

Researchers examined the unique clusters of monocytes and regulatory T cells in the circulating blood from convalescent COVID-19 patients over a prolonged period after recovery, using scRNA sequencing.

31 Mar 2022

Colonization of subventricular neurogenic niche by leukemia cells prevents the formation of new neurons

The subventricular neurogenic niche is a region of the brain where tumor cells can hide from chemotherapy treatment to reappear later, causing relapses in patients with childhood acute lymphoblastic leukemia (ALL), and preventing the formation of new neurons, as demonstrated by research led by Universidad Complutense de Madrid (UCM).

30 Mar 2022

Chemical in leafy greens could prevent infections by coronaviruses including SARS-CoV-2

Researchers discuss the use of the isothiocyanate sulforaphane for the treatment of both SARS-CoV-2 and HCoV-OC43 infections.

30 Mar 2022

Nanotherapies may benefit preterm babies with bronchopulmonary dysplasia

Very premature babies need extra oxygen and mechanical intervention to breathe, but this damages their lungs, causing a chronic lung disease called bronchopulmonary dysplasia (BPD).

30 Mar 2022

Researchers create method to track SARS-CoV-2 RBD binding in vivo

Researchers developed a method for tracking the binding of the receptor-binding domain of SARS-CoV-2 in vivo using genetically engineered extracellular vesicles that can migrate to ACE2 expressing cells.

30 Mar 2022

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

A recent viewpoint illustrated that evaluating T cell responses to COVID-19 is essential to inform public health initiatives.

29 Mar 2022

Study investigates room-temperature stable, self-amplifying RNA vaccine against SARS-CoV-2

Researchers applied a previously developed thermostable self-amplifying ribonucleic acid vaccine to COVID-19.

28 Mar 2022

Adaptive immunity against SARS-CoV-2 is persistent and robust in COVID-convalescent children

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection incites adaptive cellular immune responses. In many SARS-CoV-2 studies, peripheral blood is analyzed to study the immune responses. Now, a new study under consideration at the Nature Portfolio Journal analyzes the peripheral blood, tonsils, and adenoids of children to understand local and systemic immune responses to SARS-CoV-2.

25 Mar 2022

Flow Cytometry News and Research

Further Reading

Unique heightened aggregation of SARS-CoV-2 Delta variant spike pseudotyped particles

The effect of unsuppressed HIV on T-cell response to COVID-19

Shared gene expression signatures in type 1 diabetics treated with IL-2 and COVID-19 patients

Study characterizes SARS-CoV-2 spike-specific cluster of differentiation 4+ T-cell response

Transcriptional reprogramming of monocytes in COVID-19

Phenotypic changes in monocytes from COVID-19 patients

SARS-CoV-2 Omicron breakthrough infections induce antibodies with cross-variant neutralization potential and recall memory B cells

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Scientists explore impact of SARS-CoV-2 natural immunity on vaccine-induced immunity

Study determines the molecular signatures of monocytes and regulatory T cells in the circulating blood of COVID-19 patients

Colonization of subventricular neurogenic niche by leukemia cells prevents the formation of new neurons

Chemical in leafy greens could prevent infections by coronaviruses including SARS-CoV-2

Nanotherapies may benefit preterm babies with bronchopulmonary dysplasia

Researchers create method to track SARS-CoV-2 RBD binding in vivo

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

Study investigates room-temperature stable, self-amplifying RNA vaccine against SARS-CoV-2

Adaptive immunity against SARS-CoV-2 is persistent and robust in COVID-convalescent children

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Study confirms no preexisting B-cell immunity against SARS-CoV-2 in pre-pandemic samples

Novel nanoparticle-based COVID vaccines induce long-term neutralizing antibody response

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Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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