Flow Cytometry News and Research

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Flow cytometry is a technique for counting and examining microscopic particles suspended in a stream of fluid. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus.

Early B cell signatures predict antibody responses to mRNA-based COVID-19 vaccine

Researchers in the United States have identified both antigen-specific and antigen non-specific predictive signatures of antibody responses to Moderna’s two-dose coronavirus disease 2019 (COVID-19) vaccine that protects against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

8 Jul 2021

UPMC expert finds successful treatment for rare diseases diagnosed by newborn screenings

1It was a nagging mystery: A rare-disease expert at UPMC Children's Hospital of Pittsburgh had found a successful treatment for two of the deadliest symptoms of one of the more common classes of rare diseases diagnosed by newborn screenings, but one symptom--painful episodes of muscle breakdown that land victims in intensive care--persisted.

29 Jun 2021

Differences in monocyte subsets between severe COVID-19 and long COVID

Researchers in the United States and Costa Rica have identified differences in the proportions of monocyte subsets that occur in severe cases of coronavirus disease 2019 (COVID-19) following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and post-acute sequelae of COVID-19 (PASC), often referred to as “Long COVID”.

28 Jun 2021

Researchers study COVID-19 immune dysfunction in relation to phosphatidylserine

Often patients suffering from COVID-19 (coronavirus disease) show striking immune dysregulation - causing increased morbidity and mortality. Mechanisms for adaptive immune disturbance, lymphopenia, and thromboinflammation in COVID-19 are still poorly understood.

23 Jun 2021

Researchers identify a common mechanism underlying diverse brain disorders

Researchers at Vanderbilt University Medical Center have identified a common mechanism underlying a spectrum of epilepsy syndromes and neurodevelopmental disorders, including autism, that are caused by variations in a gene encoding a vital transporter protein in the brain.

9 Jun 2021

Pathogenic airway neutrophilia drives ARDS in Black patients with severe COVID-19 in case study

Researchers from the US used a systems immunology approach where they combined high-dimensional flow cytometry and multi-omics single-cell sequencing analyses of immune profiles taken from the airways and matching blood samples of Black/AA patients.

9 Jun 2021

Standardizable assay detects T cell responses to SARS-CoV-2 infection

Researchers in the UK have developed a high-throughput standardizable assay that accurately detects T cell responses to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

6 Jun 2021

Study examines impact of chemotherapy on mechanical properties of prostate cancer cells

Malignant tumor cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body.

28 May 2021

Could the marine compound plitidepsin promote recovery from moderate COVID-19?

A new paper by an international team of researchers describes experimental evidence of the antiviral efficacy of a marine compound called plitidepsin against SARS-CoV-2. The findings show that plitidepsin inhibits SARS-CoV at low concentrations, as observed by a thousand-fold reduction in genomic RNA and viral titers in cells exposed to the virus in culture when treated.

27 May 2021

Study attempts to standardize humoral immune Correlates of Protection (CoP) in COVID-19

A new study aims to identify antibody-based biomarkers associated with the humoral immune response that could be a standard CoP candidate for COVID-19. Further, standardization of research methods to measure these biomarkers has also been conducted.

25 May 2021

Researchers take steps to standardize correlates of protection against SARS-CoV-2

Antibodies, Antibody, Assay, Coronavirus, Efficacy, Healthcare, Pandemic, Protein, Receptor, Research, Vaccine, Virus, Coronavirus Disease COVID-19,

24 May 2021

Canopy Biosciences develops spatial proteomics assay for COVID-19

Canopy Biosciences, a Bruker Company, today announced the successful development of a new assay for examining immune response to COVID-19.

From Bruker Nano Surfaces and Metrology 21 May 2021

Methotrexate impairs immunogenicity of BNT162b2 SARS-CoV-2 vaccine in patients with immune-mediated inflammatory diseases

Researchers from Germany and the USA recently investigated the cellular and humoral immune responses of patients with IMIDs on immunomodulatory treatment to mRNA COVID-19 vaccines. The research is published on the medRxiv* preprint server.

19 May 2021

Enhanced version of CureVac’s COVID-19 vaccine could help address supply shortages

Researchers in Germany have demonstrated the preclinical effectiveness of a next-generation coronavirus disease 2019 (COVID-19) vaccine at enhancing antibody responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 May 2021

New study reveals mechanisms that result in lethal COVID-19

A new study is drawing the most detailed picture yet of SARS-CoV-2 infection in the lung, revealing mechanisms that result in lethal COVID-19, and may explain long-term complications and show how COVID-19 differs from other infectious diseases.

30 Apr 2021

Scientists design 'smart' cellular biosensors for detecting SARS-CoV-2 spike

New research led by Hana El-Samad of the University of California, San Francisco, and the Chan-Zuckerberg Biohub confirmed the beneficial use of an antiviral therapeutic called SARSNotch, which uses a combination of the SynNotch platform and de-novo designed protein binders. SARSNotch uses sentinel T cells to detect and mount a genetic response toward the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.

28 Apr 2021

Scientists identify many genes that are important in fruit flies' neuron development

Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), that then divide into precursor cells that eventually become neurons.

27 Apr 2021

CU Cancer Center researchers receive PRCRP grant to investigate metastasis

Two members of the University of Colorado Cancer Center have received prestigious Idea Awards from the U.S. Department of Defense's Peer Reviewed Cancer Research Program.

27 Apr 2021

Aigenpulse Launches CytoML 5.2: Automated Flow Cytometry With Unbiased Analysis

Aigenpulse has rolled out an update to its CytoML Experiment Suite – its automated, end-to-end, machine learning solution specifically aimed at streamlining and automating cytometry analysis at scale and replacing manual gating processes.

27 Apr 2021

Study offers insight into how damage to airways of the lung develops into pre-cancer lesions

Lung carcinomas are the leading cause of cancer-related deaths in the United States and worldwide. Lung squamous cell carcinomas (non-small cell lung cancers that arise in the bronchi of the lungs and make up approximately 30 percent of all lung cancers) are poorly understood, particularly with respect to the cell type and signals that contribute to disease onset.

26 Apr 2021

Flow Cytometry News and Research

Further Reading

Early B cell signatures predict antibody responses to mRNA-based COVID-19 vaccine

UPMC expert finds successful treatment for rare diseases diagnosed by newborn screenings

Differences in monocyte subsets between severe COVID-19 and long COVID

Researchers study COVID-19 immune dysfunction in relation to phosphatidylserine

Researchers identify a common mechanism underlying diverse brain disorders

Pathogenic airway neutrophilia drives ARDS in Black patients with severe COVID-19 in case study

Standardizable assay detects T cell responses to SARS-CoV-2 infection

Study examines impact of chemotherapy on mechanical properties of prostate cancer cells

Could the marine compound plitidepsin promote recovery from moderate COVID-19?

Study attempts to standardize humoral immune Correlates of Protection (CoP) in COVID-19

Researchers take steps to standardize correlates of protection against SARS-CoV-2

Canopy Biosciences develops spatial proteomics assay for COVID-19

Methotrexate impairs immunogenicity of BNT162b2 SARS-CoV-2 vaccine in patients with immune-mediated inflammatory diseases

Enhanced version of CureVac’s COVID-19 vaccine could help address supply shortages

New study reveals mechanisms that result in lethal COVID-19

Scientists design 'smart' cellular biosensors for detecting SARS-CoV-2 spike

Scientists identify many genes that are important in fruit flies' neuron development

CU Cancer Center researchers receive PRCRP grant to investigate metastasis

Aigenpulse Launches CytoML 5.2: Automated Flow Cytometry With Unbiased Analysis

Study offers insight into how damage to airways of the lung develops into pre-cancer lesions

Flow Cytometry eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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