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Influenza (the flu) is a contagious respiratory illness caused by influenza viruses. It can cause mild to severe illness, and at times can lead to death. The best way to prevent the flu is by getting a flu vaccination each year. Every year in the United States, on average 5% to 20% of the population gets the flu; more than 200,000 people are hospitalized from flu complications, and; about 36,000 people die from flu-related causes. Some people, such as older people, young children, and people with certain health conditions, are at high risk for serious flu complications.
Scientists discover vaccine-induced antibodies that can counteract varied strains of influenza virus

Scientists discover vaccine-induced antibodies that can counteract varied strains of influenza virus

Scientists have identified three types of vaccine-induced antibodies that can neutralize diverse strains of influenza virus that infect humans. [More]
New on-line resource allows user to virtually test effectiveness, specificity of potential drug

New on-line resource allows user to virtually test effectiveness, specificity of potential drug

Inside the human body, the same drug can interact with multiple molecules. This phenomenon is known as 'polypharmacology' and, according to the interaction, a drug can cure a disease or cause side effects in the patient. [More]
Penn researchers construct model to examine how immune system may evolve to conquer HIV

Penn researchers construct model to examine how immune system may evolve to conquer HIV

It has remained frustratingly difficult to develop a vaccine for HIV/AIDS, in part because the virus, once in our bodies, rapidly reproduces and evolves to escape being killed by the immune system. [More]
First clinical study for Zika vaccine to begin in Canada

First clinical study for Zika vaccine to begin in Canada

Université Laval's Infectious Disease Research Centre and Centre de recherche du CHU de Québec-Université Laval are proud to announce that the first clinical study for a Zika vaccine in Canada is set to begin in Quebec City. [More]
Intranasal vaccine may provide long-term protection against multiple flu strains

Intranasal vaccine may provide long-term protection against multiple flu strains

Intranasal flu vaccines may be able to provide long-lasting protection against pandemic flu strains, according to a new study from immunologists at Columbia University Medical Center. [More]
Preventing zoonotic diseases from pets to people: an interview with Dr Monique Éloit, OIE Director General

Preventing zoonotic diseases from pets to people: an interview with Dr Monique Éloit, OIE Director General

Zoonotic diseases are diseases or infections which are naturally transmissible from animals to humans, as defined in the OIE Terrestrial Animal Health Code. [More]
H3N2v-neutralizing antibodies produced from human subjects given candidate vaccine

H3N2v-neutralizing antibodies produced from human subjects given candidate vaccine

Influenza A viruses are responsible for seasonal disease outbreaks in humans. Influenza A also circulates among bird and some mammal populations and periodically crosses between species. [More]
New research highlights need to abandon modern hygiene hypothesis

New research highlights need to abandon modern hygiene hypothesis

The July issue of Perspectives in Public Health (published by the Royal Society of Public Health) takes an objective view of ongoing research showing that the hygiene hypothesis – the idea that allergies are the price we are paying for our “modern obsession with cleanliness” – is a misleading misnomer. [More]
Key differences in immune response may explain young children’s proneness to infecion

Key differences in immune response may explain young children’s proneness to infecion

Schools are commonly known as breeding grounds for viruses and bacteria, but this may not necessarily be linked to hygiene. [More]
New IDSA guidelines focus on diagnosis, treatment of deadly aspergillosis

New IDSA guidelines focus on diagnosis, treatment of deadly aspergillosis

New therapies are improving care, but early diagnosis remains critical in the effective treatment of invasive, a potentially deadly fungal infection, according to new guidelines released by the Infectious Diseases Society of America and published in the journal Clinical Infectious Diseases. [More]
TSRI scientists develop new strategy to design potential HIV vaccine candidates

TSRI scientists develop new strategy to design potential HIV vaccine candidates

Want to catch a criminal? Show a mugshot on the news. Want to stop HIV infections? Get the immune system to recognize and attack the virus's tell-tale structure. That's part of the basic approach behind efforts at The Scripps Research Institute to design an AIDS vaccine. [More]
Researchers identify exact origin of 2009 swine H1N1 flu pandemic

Researchers identify exact origin of 2009 swine H1N1 flu pandemic

The 2009 swine H1N1 flu pandemic — responsible for more than 17,000 deaths worldwide — originated in pigs from a very small region in central Mexico, a research team headed by investigators at the Icahn School of Medicine at Mount Sinai is reporting. [More]
Research shows enveloped viruses could survive on toys long enough to cause infection

Research shows enveloped viruses could survive on toys long enough to cause infection

Certain viruses, such as influenza, could survive on children's toys long enough to result in exposures, placing children at risk for getting infectious diseases, according to researchers at Georgia State University. [More]
Mobile devices of healthcare workers often contaminated by viral RNA

Mobile devices of healthcare workers often contaminated by viral RNA

In clinical settings, mobile phones benefit patients by placing useful data and information at the fingertips of health professionals during interactions on the ward. [More]
Switch to rituximab shows anti-inflammatory effect in relapsing-remitting MS

Switch to rituximab shows anti-inflammatory effect in relapsing-remitting MS

Rituximab may be an attractive treatment option for patients with relapsing-remitting multiple sclerosis, suggest phase II study findings showing its efficacy in controlling inflammatory activity. [More]
First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

Scientists at the University of Massachusetts Medical School have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication. [More]
RVFV uses cancer pathway to hijack host cell and cause infection

RVFV uses cancer pathway to hijack host cell and cause infection

Viruses can't live without us -- literally. As obligate parasites, viruses need a host cell to survive and grow. Scientists are exploiting this characteristic by developing therapeutics that close off pathways necessary for viral infection, essentially stopping pathogens in their tracks. [More]
T memory cells with naive phenotype can help boost immunity in older adults

T memory cells with naive phenotype can help boost immunity in older adults

Sixty-five is the age when many people retire, kick back and take it easy. And so it often is with the human immune system. [More]
Study provides insights into new pathways to generate universal vaccine against influenza viruses

Study provides insights into new pathways to generate universal vaccine against influenza viruses

Diverse antibodies induced in humans by vaccination with an avian influenza virus vaccine may offer broader, more durable protection against multiple strains of influenza than today's vaccines typically provide, according to a study led by Florian Krammer, PhD, Assistant Professor in the Department of Microbiology at the Icahn School of Medicine at Mount Sinai, and Patrick Wilson, PhD, Associate Professor in the Department of Medicine at the University of Chicago. [More]
Far-UVC light can combat deadly scourge of drug-resistant surgical site infections

Far-UVC light can combat deadly scourge of drug-resistant surgical site infections

Scientists from the Center for Radiological Research at Columbia University Medical Center have shown that a narrow wavelength of ultraviolet (UV) light safely killed drug-resistant MRSA bacteria in mice, demonstrating a potentially safe and cost-effective way to reduce surgical site infections, a major public health concern. [More]
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